Skin boosters and HA fillers in Marylebone at Dr Joney De Souza Clinic for natural, long lasting radiance. Book your consultation today for Mesotherapy, Polynucleotides or Profhilo.
Hydrate with Skin Boosters, Sculpt and define with fillers
At the Dr Joney De Souza Clinic in Marylebone, treatment plans are designed around what you are noticing, not a one size fits all solution. By addressing the underlying cause of each concern, we are able to restore skin quality, support facial structure and maintain a natural, refined appearance.


TV presenter Cat Deeley recently spoke openly about her approach to aesthetic treatments in Good Housekeeping, describing how she prioritises natural looking results that support skin quality and confidence. In the article, Cat highlights the benefits of having skin booster treatments with Dr Joney De Souza as part of her routine for maintaining hydration and a fresh-looking complexion.
“I want something that I can go in, do and know it’s going to keep on delivering.”


Skin boosters are designed to improve skin quality rather than change facial shape. They work by hydrating the skin from within and stimulating collagen to improve texture, elasticity and radiance.
Profhilo is carefully injected at strategic points beneath the skin. Once in place, the hyaluronic acid draws water into the deeper layers, delivering intense hydration and nourishing the skin from within. Over the following weeks, the presence of the hyaluronic acid also stimulates fibroblasts, which in turn boost the production of collagen and elastin.
This dual action results in:
Deep, lasting hydration
Improved elasticity and firmness
Smoother texture and tone
A more radiant, youthful complexion
Because the product gradually disperses and stimulates multiple types of collagen and elastin, the effects build naturally rather than instantly, creating a refined and authentic result.








Skinvive is a next generation skin booster by the popular filler brand Juvederm that works within the superficial layers of the skin to improve hydration, smoothness and luminosity. It uses a specialised micro-droplet hyaluronic acid (HA) formulation that distributes evenly beneath the skin’s surface, attracting water and supporting the skin’s natural ability to reflect light. The result is softer, more hydrated skin with finer texture and enhanced radiance.
Unlike traditional dermal fillers that restore volume or change contour, Skinvive focuses on skin quality itself. It is ideal for patients who want to:
Improve dull or dehydrated skin
Smooth fine texture irregularities
Reduce the appearance of early fine lines
Boost overall skin softness and glow


Hyaluronic acid (HA) fillers are designed to restore lost volume, support facial contours and rebalance proportions where ageing or genetics have reduced structural definition. Hyaluronic acid is a naturally occurring substance that integrates seamlessly into soft tissue, allowing Dr Joney De Souza to replace volume with precision and control. Whether the concern is hollowing under the eyes, a recessed chin, flattened cheeks or loss of jawline definition, hyaluronic acid fillers such as Teosyal can provide targeted support while maintaining natural movement and expression.
The primary benefit of HA fillers is their versatility. They can restore contour, soften deeper lines and provide foundational support where tissues have lost their resilience. Unlike skin boosters, which focus on hydration, HA fillers work at deeper levels to reshape and enhance structure. They are reversible and adjustable, giving patients a predictable and flexible pathway to refined, balanced aesthetic improvement. If you are considering a HA filler treatment ask us a question on WhatsApp or ask the team to give you a call back.


Collagen stimulating fillers such as Radiesse work differently to traditional HA fillers and Skin Boosters. While they provide immediate structural support, their key benefit is their ability to encourage the body’s own collagen production over time. Radiesse is formulated with microspheres that stimulate fibroblasts, prompting the skin and soft tissues to produce new collagen. This leads to a gradual strengthening and thickening of the tissue, improving firmness and definition in areas prone to laxity.
Radiesse is particularly suited to patients who want long term improvement in skin quality and support rather than just volume replacement. It is widely used to enhance jawline definition, improve lower face firmness and reduce the appearance of early sagging. The result is a more robust tissue structure that continues to improve over several months, offering both immediate and durable benefits without altering the natural features of the face.

Our pricing reflects the bespoke, medically led care provided at the Dr Joney De Souza Clinic in Marylebone. Depending on your practitioner and due to every treatment is personalised to your concerns and aesthetic goals, we list starting prices for guidance. Final costs will be confirmed following your consultation with Dr Joney, where your tailored plan and most suitable treatment options are discussed.
| Treatment | Price |
|---|---|
HA Dermal Filler | £335* |
Profhilo | £450* |
Radiesse | Give us a call |
Our patients return to us year after year for natural, balanced results. Every review reflects our commitment to precision, safety and a personalised approach to aesthetic care.
Now that you have a clearer understanding of the differences between skin boosters such as Profhilo and Skinvive, hyaluronic acid fillers and collagen stimulating treatments, you may still have questions about which option is most suitable for you. The answers below address some of the most common queries we receive. If you would prefer personalised advice, our team is always happy to help and guide you through your options.
Profhilo is a high concentration hyaluronic acid injectable designed to deeply hydrate the skin and stimulate collagen and elastin production. It improves skin firmness, elasticity and texture without adding volume.
Profhilo spreads beneath the skin to attract moisture and support the skin’s own regenerative processes. Over time, this leads to improved hydration, smoother texture and stronger tissue quality.
Skinvive is a micro droplet hyaluronic acid treatment that improves surface hydration, texture and glow. It enhances the skin’s ability to reflect light and feel softer without adding volume.
While both improve hydration and skin quality, Skinvive works more superficially to refine texture and radiance, whereas Profhilo works more broadly within the skin’s deeper layers to stimulate collagen and firmness.
HA fillers are injectable gels that replace lost volume, enhance contour and support facial structure. Products like Teosyal are tailored to specific areas such as cheeks, lips, chin or jawline.
HA fillers are effective for volume loss, weak chin, hollow temples, flattened cheeks, loss of jawline definition and deep static lines.
Collagen stimulators like Radiesse provide structural support immediately and encourage the body to produce new collagen over time, improving skin firmness and support.
Every treatment at the Dr Joney De Souza Clinic begins with a thorough consultation. During this appointment, Dr Joney takes time to understand your concerns and aesthetic goals, assess your skin quality, hydration, elasticity and facial structure, and identify the most appropriate treatment approach for you. He will explain how the recommended treatment works, what improvements you can expect and whether combining different treatments may help achieve the most refined and natural result.
Once your personalised plan is agreed, the skin is gently cleansed and a topical anaesthetic may be applied to ensure comfort where required. Using precise injection techniques, Dr Joney administers the treatment in carefully selected areas, working at the appropriate depth depending on the product used. Each treatment is performed with accuracy and restraint to support natural looking improvement, whether the goal is enhanced hydration, improved skin quality, restored structure or collagen stimulation. Discomfort is minimal and there is no significant downtime for most injectable treatments.
Based at 49 Blandford Street in Marylebone, Dr Joney De Souza Skin & Laser Clinic is known for its refined, personalised approach to aesthetic medicine. Under the expert care of Dr Joney, every treatment is tailored to enhance natural beauty and maintain long-term skin health.
Dr Joney will advise you on aftercare, such as avoiding strenuous exercise or massaging the area for 24 hours. Many patients choose to book a review appointment around two weeks later, where any fine-tuning can be carried out if necessary.
Results typically last between three to six months, depending on your individual response and the area treated. With regular maintenance treatments, you’ll notice smoother skin, softer lines, and a fresher, more relaxed appearance that still looks entirely natural.

