PRF, or platelet-rich fibrin, is a newer generation of PRP or Platelet-Rich Plasma preparation that can be used in a variety of treatments to regenerate collagen and reverse the signs of aging.  PRF in London at Dr Joney De Souza Clinic can be combined with LED light to achieve an even more effective result.

This treatment is also excellent for stimulating hair growth and is a frequently considered treatment for hair loss. We also carry out PRP for hair loss in London at our clinic in Marylebone.


PRF, or platelet-rich fibrin, is a newer generation of PRP or Platelet-Rich Plasma preparation that can be used in a variety of treatments to regenerate collagen and reverse the signs of aging. 

As with PRP, your own blood is taken, and goes through a process of centrifugation where it is essentially spun in a machine which separates out the platelets and other components suspended in bloody plasma.  These other components include fibrin matrix, which is a protein involved in blood clotting, as well as white blood cells. 

Platelets and Fibrin are rich in growth factors which essentially perform an array of anti-aging, skin-benefiting functions, including boosting the skin’s collagen building process.  The PRF releases slower and therefore has a longer anti-aging effect.

PRF is a completely natural aesthetic treatment and can be used as to help rejuvenate the appearance of your face, under eye area or as an effective treatment for hair loss and stimulating hair regrowth.  PRF can help restore a more youthful and smoother appearance and continue to work overtime by promoting the generation of new collagen.  A series of treatments are often advised to achieve best results.

What our clients say

“I wasn't keen on dermal fillers and sought Dr De Souza because of his reputation for natural results and becuase he also used to teach his techniques to other doctors and surgeons, so is an expert. My skin has never looked so good”


  • No. of treatments       Initially a course of 2 treatments spaced six to eight weeeks apart
  • Procedure Time         60 minutes
  • Anaesthetic                 A topical anaesthetic may be applied as needed
  • Sensitivity Period       3 days
  • Back to work              After 2 days
  • Full Recovery             3 – 5 days
  • Duration of results     Maximum results after 6 months but skin continues to improve over time. 


What can PRF do for me?

PRF is an effective treatment for improving skin texture and .  Skin becomes luminescent, hydrated, nourished, and firmer and texture is improved.

Who is suitable?

You will be invited for a medical consultation to assess your suitability for this treatment.

What’s the treatment like?

Platelet-Rich Fibrin (PRF) is a by-product of blood (plasma) that is rich in platelets.  

Dr Joney De Souza will take a small amount of your blood and place this in a centrifuge to separate the red blood cells from the platelet rich plasma containing growth factors.  The plasma is then re-injected into treatment area – it can be administered either in multiple micro-injections, like Mesotherapy or Dermal Hydrating Treatments, directly into lines and wrinkles, like a filler, or deeper into the dermis, like a volumiser. 

The process should be no more painful than any other injectable procedure, but the treatment area might be numbed beforehand with a topical local anaesthetic cream. Some practitioners combine this with other ‘self-heal’ treatments, like Medical Micro-Needling to enhance the results.

What happens afterwards?

There might be a small amount of redness or swelling at injection site, but this should fade quickly. You might also have some bruising where the blood was taken, but again this won’t last. One thing to avoid is taking aspirin or any anti-inflammatory drugs.  This isn’t a one-off treatment – a course of treatments is usually recommended and it might take up to six months for the results of platelet rich plasma therapy to show, but the real benefit is that they should be permanent.

Improvement of skin texture and tone are noticeable within three weeks. Full collagen regeneration takes three months.

Treatment Prices

You can rest assured that we only use the highest quality UK sourced products at our clinic, this includes only the most premium dermal fillers and the most advanced FDA approved technologies. With the highest levels of customer service and expertise, our focus is on you - just have a look at our amazing reviews.

PRP session   550 | 900**
* 1 treatment session ** 2 treatment sessions | Sessions 4 to 6 weeks apart

How can I book an appointment?

Contact Dr Joney De Souza Skin & Laser Clinic today on 0207 043 0748, book online now or email us at or visit us at 49 Blandford Street, Marylebone, London W1U 7HH