
Wrinkled skin reflects natural changes in skin structure over time. Led by Medical Director Dr Joney De Souza, our medical team focuses on understanding why wrinkles form before considering treatment.
Wrinkled skin refers to deeper, more established lines and creases that form as skin structure changes. Wrinkles may appear in areas of repeated movement or in regions where skin has thinned and lost elasticity. Wrinkled skin differs from fine lines in depth and permanence, and often reflects longer-term changes in collagen and support.
Botox is commonly used to reduce wrinkles by relaxing the facial muscles that cause repeated skin creasing. Wrinkles form over time as expressions such as frowning or squinting fold the skin in the same areas. Therefore, by limiting this muscle movement, Botox allows the skin to smooth out and prevents lines from deepening. As a result, the face looks softer, more rested, and refreshed while natural expression is maintained.

Wrinkled skin develops due to multiple factors acting together.
These may include:
Gradual loss of collagen and elastin
Repeated facial movement over time
Sun exposure and environmental damage
Thinning and dehydration of the skin
Genetic influences
The pattern and severity of wrinkles vary between individuals.
Endolift can help improve wrinkles by tightening skin and stimulating collagen from within. Wrinkles develop as skin loses firmness and structural support over time. Therefore, by delivering targeted laser energy beneath the skin, Endolift encourages skin contraction and collagen renewal. As a result, the skin appears smoother, firmer, and more refreshed without the need for surgery.

Assessment focuses on whether wrinkles are primarily related to movement, skin quality, structural support or a combination of factors. Our medical team evaluates skin thickness, elasticity and facial dynamics.
This allows us to explain which approaches may help soften wrinkles and which changes are less responsive to non-surgical treatment.


Anti-wrinkle injections are often discussed where wrinkles are primarily related to repeated muscle movement.
Improvement depends on the type and cause of wrinkles. Options discussed at our clinic may include anti-wrinkle injections, dermal fillers, polynucleotide treatments, skin boosters and UltraClear laser resurfacing. The aim is gradual softening and improved skin quality.
No. Wrinkles are deeper and more established, while fine lines are typically shallower and may fluctuate.
No. Treatments aim to soften wrinkles and support skin health rather than fully reverse ageing.
They often become more noticeable over time as collagen and elasticity decline.
Skincare can support skin health, but deeper wrinkles usually require in-clinic treatments for visible improvement.
No. Many people choose not to treat wrinkles once they understand why they develop and how they may change.

Our team would love to hear from you. Whether you have questions, need guidance, or simply want to explore your treatment options, we’re here to support you every step of the way. If you would like to place an online booking you can do this via our online booking system.
Dr Joney De Souza Skin and Laser Clinic is located in central Marylebone and is easily accessible by public transport or car, with Bond Street, Oxford Circus and Baker Street Underground stations all just a short walk away. For those driving, paid on-street parking and nearby public car parks are available, making the clinic convenient to reach from across London, including Mayfair and Soho.