PicoSure Laser London

Skin rejuvenation with Picosure Laser is the latest and most advanced skin revitalisation treatment with very little downtime. It can dramatically reduce pigmentation, and melasma whilst boosting collagen and reducing lines and wrinkles.

PicoSure Technology

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Procedure time
30 to 45 minutes
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Back to work
Same day
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No. of treatments
3-session initial course
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Duration of results
Improves with successive sessions
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Sensitivity period
24 to 48 hours

Who Is PicoSure Laser For?

Clearer, brighter, more even skin is exactly what PicoSure laser is built for. It lifts stubborn pigmentation and dark spots without stripping the surface or taking you out of your day. Also known as pico laser, it leaves your natural skin tone looking fresher and more luminous. If pigmentation has been hard to shift and you cannot spare much downtime, PicoSure is a gentle laser for pigmentation you can fit into a London lunch break.

Most patients come to us with one or more of these concerns:

  • Sun damage, age spots and other dark spots
  • Melasma and hormonal pigmentation
  • Post-inflammatory hyperpigmentation, including after acne
  • Pigmented dark circles under the eyes
  • Freckles and uneven skin tone
  • Dull or lacklustre complexion
  • Superficial acne scarring
  • General skin rejuvenation and collagen stimulation

PicoSure suits a wide range of skin tones. That includes medium and darker complexions, which carry a higher risk of side effects with older lasers. Your specialist always carries out a consultation and patch test before your first session, to confirm suitability and set expectations. You can also read how PicoSure targets pigmentation before you book.

Related concerns: this treatment helps with pigmentation and age spots.

What Is PicoSure Laser?

PicoSure is a picosecond laser that sends ultrashort bursts of energy into the skin, each lasting a trillionth of a second. Rather than heating the skin, it creates a photomechanical PressureWave just beneath the surface. The surrounding tissue absorbs far less heat than with older nanosecond or millisecond lasers. This advanced technology lets PicoSure treat pigmentation that older systems could not safely handle, especially in darker skin tones.

At Dr Joney De Souza Clinic in Marylebone, PicoSure uses the Focus lens. It concentrates energy into precise zones to break down pigment and prompt fresh collagen. You get real improvements in pigmentation, brightness and skin quality, with minimal downtime and no removal of the skin surface. PicoSure treatment in London comes as a single session or a short course of two or three, tailored to your skin.

How Does PicoSure Laser Work?

PicoSure delivers picosecond pulses of laser light at 755nm, tuned to the melanin pigment in your skin. Each pulse shatters the pigment into microscopic fragments, which your body then clears naturally. The Focus lens adds a gentle pressure response in the deeper layers. That wakes up new collagen and elastin, without the heat that causes downtime or upsets sensitive skin. This is what makes pico laser resurfacing so effective on both pigmentation and the early signs of ageing.

If you want the background first, our guide on how to get rid of pigmentation with laser explains the approach in plain terms.

Key Benefits of PicoSure Laser

  • Targets pigmentation, melasma, age spots and post-inflammatory hyperpigmentation
  • Suitable for a broad range of skin tones, including darker complexions
  • Minimal downtime compared to ablative laser treatments such as CO2
  • Non-ablative treatment: no removal of the skin surface
  • Results visible after a single session, with progressive improvement over a course
  • Clinically proven technology with a strong international safety record
  • Carried out by specialist practitioners with specific PicoSure training at the clinic
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Consultation and skin assessment

Before any PicoSure laser session begins, your specialist conducts a thorough consultation to assess your skin type, degree of pigmentation and treatment goals. In practice, this allows the practitioner to select the correct energy settings and handpiece for your skin tone and concern. Additionally, your specialist carries out a patch test at this stage to confirm your skin responds as expected and to ensure the treatment is appropriate for you.

Skin preparation and numbing

On the day of your appointment, your specialist cleanses the treatment area to remove any makeup, oils or SPF. Next, your specialist applies a topical numbing cream and leaves it for 20 to 30 minutes to ensure your comfort throughout the session. As a result, most patients find PicoSure laser treatment far more comfortable than they anticipated, particularly for larger areas such as the full face.

The PicoSure laser session

Once your specialist removes the numbing cream and passes the PicoSure handpiece across the treatment area in a series of controlled pulses. In practice, each pulse delivers an ultrashort burst of energy lasting just picoseconds, generating a photomechanical PressureWave beneath the skin. For pigmentation concerns, the Focus lens attachment concentrates energy into precise zones to shatter pigment particles without generating significant heat in the surrounding tissue.

Cooling and immediate aftercare

Immediately after the laser session, your specialist applies a cooling gel or soothing mask to the treatment area. As a result, any redness or warmth settles more quickly, and the skin settles calmly before you leave the clinic. Additionally, your specialist applies SPF to protect your skin before you step outside and provides a written aftercare guide to take home.

Results and skin response at home

In the days following treatment, your skin may appear slightly pink or feel mildly sensitive, particularly in the first 24 to 48 hours. However, for most patients these effects are minimal and daily activities can resume the same day or the following morning. Overall, the improvement in pigmentation and skin radiance builds gradually over two to four weeks as the body clears the treated pigment particles and produces new collagen.

Follow-up and course planning

After each session, your specialist reviews your skin’s response and adjusts the plan if needed. In most cases, a course of three sessions spaced four to six weeks apart produces the most significant and lasting results for pigmentation. Furthermore, your specialist will advise on a maintenance schedule and any skincare products that will support your results between sessions.

Results, review and maintenance

Over the two to four weeks following each session, your body processes the fragmented pigment and produces new collagen, gradually improving skin clarity and brightness. At your review, your specialist assesses your skin’s progress and adjusts the next session’s energy settings accordingly. For most concerns, three sessions spaced four to six weeks apart deliver optimal results. Consequently, patients whose pigmentation returns over time, particularly those prone to melasma, often benefit from a single maintenance session once or twice a year to sustain their results.

PicoSure Laser Before & After Results in Marylebone

The following results show improvements in skin tone, texture and pigmentation achieved after a course of PicoSure laser treatment at Dr Joney De Souza Clinic.

Before
After
Before
After
Before
After
Before
After

Your PicoSure Treatment Journey

Most patients get their best results from a course of three PicoSure sessions, spaced four to six weeks apart. Even a single session gives a visible lift in brightness and a softening of pigmentation. Your specialist shapes every plan around how your skin responds and what you want to achieve. They review progress at each visit before going further.

Before your PicoSure treatment

As your consultation approaches, your specialist will advise you to avoid sun exposure and to pause vitamin A products such as retinol or tretinoin for at least one week beforehand. Additionally, you should arrive with clean skin, free of SPF, makeup and active skincare on the day of your appointment. In practice, your specialist carries out a patch test at your first appointment to confirm your skin’s suitability and to set realistic expectations for the results ahead. Before committing to a course, you are welcome to discuss any questions or concerns with your specialist at that initial consultation.

During your PicoSure session

On the day of treatment, your specialist cleanses your skin and applies a topical numbing cream for 20 to 30 minutes before the laser session begins. In practice, the laser delivers a series of controlled pulses across the treatment area, each lasting just picoseconds. However, because of the numbing cream, most patients describe the sensation as a mild snapping or warmth rather than significant discomfort. Overall, a full-face session typically takes 20 to 30 minutes from start to finish, after which your specialist applies cooling and SPF before you leave the clinic.

After your PicoSure treatment

In the 24 to 48 hours following treatment, your skin may appear slightly pink or feel mildly warm and sensitive. As advised at your consultation, SPF 50 should be worn daily throughout your course and for at least four weeks after your final session. Additionally, it is important to avoid saunas, steam rooms, intense exercise and direct sun exposure for 48 hours after treatment. After each session, your skin’s brightness and evenness will improve gradually over two to four weeks as the body processes the treated pigment, with full results visible four to six weeks after each appointment.

Why Dr Joney De Souza Clinic?

At Dr Joney De Souza Clinic in Marylebone, specialist practitioners trained specifically in PicoSure carry out every laser session. Dr Joney De Souza oversees the clinical side. Every plan is built to a medical standard, weighing your skin history, any concerns and the right energy settings for your skin type and tone.

  • Specialist practitioners with specific PicoSure training and pigmentation expertise
  • Consultation and patch test before every first treatment
  • Experience treating all skin tones, including darker complexions
  • Central Marylebone location, minutes from Baker Street and Bond Street and within easy reach of Knightsbridge, Mayfair and the West End
  • Dedicated aftercare guidance and a progress review at every appointment
  • No pressure to commit to a full course at consultation

A Medical Standard of Care

Dr Joney De Souza has spent over 20 years in aesthetic medicine in London, with a reputation built on clinical results and honest advice. What sets the clinic apart is not only the technology but the quality of assessment behind every treatment. The clinic will never recommend something that is not right for your skin, and the team talks through realistic outcomes before you commit. Patients come back not just for the results, but for the trust built over years of care.

Where our PicoSure differs. We use both PicoSure heads, including the Focus lens that drives skin rejuvenation, not only the head that clears pigmentation. Many clinics use the pigmentation head alone, because the Focus tip costs the clinic more. We also include around 30 minutes of numbing and a full 45-minute treatment, rather than a rushed session with none. The result is more thorough and more comfortable.

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PicoSure Laser Pricing

Trained specialist practitioners carry out every PicoSure session at Dr Joney De Souza Clinic. Prices depend on the area treated and whether you choose a single session or a course. A course of three usually gives the strongest, longest-lasting improvement for pigmentation. If you are weighing up pico laser treatment near you, our guide to PicoSure laser cost in London sets out what to expect.

Which PicoSure Treatment Is Right for You?

  • Full face: ideal for widespread pigmentation, melasma, age spots and all-over brightening
  • Face and neck: recommended when pigmentation extends beyond the face or décolletage
  • Targeted areas (eye, mouth, scars): suited to isolated pigmentation or post-inflammatory spots
  • Course of 3: the most common choice for persistent or diffuse pigmentation concerns

PicoSure Laser Pricing

PicoSure is an Associate treatment. Final pricing confirmed at consultation.

Associate (£)Associate x2(£)Associate x3(£)

Face

420

840

1,160

Face & Neck

550

1,100

1,500

Face, Neck & Decolletage

700

1,400

1,900

Neck

350

700

950

Neck & Decolletage

500

1,000

1,400

Decolletage

350

700

950

Eye area

250

500

675

Mouth area (‘smoker’s lines’)

250

500

675

Scars to Small (10×10 cm)

250

500

675

Prices are per session, inclusive of specialist consultation. All courses apply to the same treatment area and are non-transferable.
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Pair PicoSure with Fraxel 1540 for Complete Skin Renewal

PicoSure is outstanding at lifting surface pigmentation, melasma and uneven tone. Some patients also have textural concerns, such as enlarged pores, fine lines or superficial scarring. Pairing PicoSure with Fraxel 1540 gives a more complete result. PicoSure handles colour and pigmentation, while Fraxel 1540 works on texture and rebuilds collagen deeper down. Patients who complete a planned sequence of both often see a fuller improvement than either treatment delivers alone.

The clinic offers both. Many patients do well on a tailored combination, with sessions spaced to allow full recovery between each. The two lasers use different wavelengths and mechanisms, so they complement rather than compete. If you are weighing up both, your specialist can map out the right sequence and timing at your first consultation.

Explore Fraxel 1540
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Frequently Asked Questions About PicoSure Laser

Below are answers to the questions we hear most about PicoSure laser treatment at Dr Joney De Souza Clinic in Marylebone. If your question is not covered, the team is a message away on WhatsApp or through the form on this page.

What conditions does PicoSure laser treat?

PicoSure is clinically used to treat a wide range of pigmentation and skin concerns. In practice, the treatment is most commonly chosen for sun damage and age spots, post-inflammatory hyperpigmentation, melasma, freckles, uneven skin tone, dull complexion, superficial acne scarring and overall skin rejuvenation. Additionally, PicoSure with the Focus lens is particularly effective for collagen stimulation, improving overall skin texture and brightness even in patients without significant pigmentation.

How many PicoSure sessions will I need?

The number of sessions depends on the type and severity of your concern. However, for most pigmentation conditions, a course of three sessions spaced four to six weeks apart produces the most consistent results. In some cases, patients with lighter or more superficial pigmentation see meaningful improvement after a single session, while more persistent conditions such as melasma may benefit from additional treatments. In practice, your specialist will review your skin after each session and adjust the plan accordingly.

Is PicoSure suitable for all skin tones?

Skin Type, Suitability and Safety

PicoSure is suitable for a broad range of skin tones, including medium and darker skin types that carry a higher risk of side effects with older laser technologies. In practice, the picosecond pulse duration generates less heat in the surrounding tissue than nanosecond or millisecond lasers, reducing the risk of post-inflammatory hyperpigmentation in patients with higher melanin levels. However, a consultation and patch test are always conducted before your first session to confirm suitability for your specific skin type and concern.

Is PicoSure safe for darker skin?

Yes. PicoSure has a strong safety profile for Fitzpatrick skin types IV, V and VI when used at appropriate settings. In practice, the clinic’s practitioners are experienced in treating a diverse range of skin tones and will adjust energy settings based on your consultation assessment. As a result, patients with darker skin tones achieve effective pigmentation reduction while minimising the risk of post-inflammatory hyperpigmentation.

How is PicoSure different from older laser treatments?

Older Q-switched nanosecond lasers deliver pulses lasting one billionth of a second. PicoSure, however, delivers pulses lasting one trillionth of a second, generating a photomechanical PressureWave rather than primarily thermal energy. In practice, this means the surrounding tissue absorbs significantly less heat, reducing the risk of burning or post-inflammatory pigmentation. As a result, PicoSure can treat conditions that older technologies could not safely address, particularly in patients with darker skin tones or sensitive skin.

What does a PicoSure session feel like?

Comfort, Duration and Recovery

Most patients describe PicoSure as a series of snaps or mild warmth on the skin surface. However, because your specialist applies a topical numbing cream before the session, the majority of patients find the treatment comfortable and well tolerated. In practice, a full-face session takes 20 to 30 minutes from the point the laser begins. After treatment, the skin typically feels warm and appears slightly pink, which usually settles within a few hours to 24 hours. Overall, most patients return to their normal routine the following day.

What is the PicoSure Focus lens?

The Focus lens is a specialised attachment for the PicoSure handpiece that concentrates laser energy into a series of precise, high-intensity zones within the skin. In practice, this creates a pattern of treated zones surrounded by unaffected tissue, which accelerates the healing response and stimulates collagen and elastin production. Specifically, the Focus lens is used for skin rejuvenation and difficult pigmentation conditions such as melasma, where broad-field treatment with the standard handpiece would carry too much risk for certain skin types.

Is there downtime after PicoSure?

PicoSure involves minimal downtime compared to ablative laser treatments such as CO2 or UltraClear. In practice, most patients return to work the following day, with some able to resume normal activities the same afternoon after applying makeup to cover any residual redness. However, we advise patients to avoid high-intensity exercise, saunas and direct sun exposure for 48 hours after treatment, and to wear SPF 50 daily throughout their course. Overall, the combination of short recovery time and visible results is one of the most frequently cited reasons patients choose PicoSure over alternative treatments.

When will I see results from PicoSure?

Results, Longevity and Maintenance

Many patients notice an immediate brightening effect after their first session, particularly in areas of superficial pigmentation. However, the full improvement in pigmentation and skin radiance develops over two to four weeks after each session as the body processes the treated pigment particles. In most cases, the most significant change is visible between the second and third session of a course. Consequently, it is important not to assess final results until four weeks after the last treatment.

How long do PicoSure results last?

Results vary depending on the condition treated and your exposure to triggering factors such as sun exposure and hormonal changes. In most cases, pigmentation removed during a course of PicoSure does not return to the same degree, provided patients maintain good sun protection habits. However, melasma in particular can be influenced by hormones, heat and UV exposure, meaning some patients benefit from annual maintenance sessions to sustain their results. In practice, your specialist will advise on a maintenance plan appropriate to your skin and lifestyle.

Can PicoSure be combined with other treatments?

Yes. PicoSure combines well with several treatments offered at the clinic. In practice, many patients pair a course of PicoSure with Profhilo or polynucleotides for additional hydration and skin quality improvements after laser treatment. Additionally, Fraxel 1540 can be used alongside PicoSure in a planned sequence to target both pigmentation and skin texture. However, your specialist will advise on appropriate spacing between treatments to allow your skin to recover fully between each session.

Do you use the PicoSure Focus lens for rejuvenation?

Yes. We use both PicoSure heads, including the Focus lens, so you receive pigmentation clearance and skin rejuvenation, not only one of the two.

Is numbing included, and how long is the PicoSure treatment?

Yes. We allow around 30 minutes of numbing and a full 45-minute treatment, for comfort and a thorough result.

Why might your PicoSure cost more than some clinics?

Because you receive both treatment heads, proper numbing time and a full-length treatment, rather than a rushed single-head session.

PicoSure vs Other Laser Treatments

The right laser depends on your skin concern, your skin tone and how much downtime you can take. Different systems work on different principles and suit different conditions. Below is how PicoSure compares to the other laser options at Dr Joney De Souza Clinic and beyond. Our explainer on PicoSure and erbium laser goes a level deeper.

Related reading: is PicoSure laser safe.

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4.9 ★★★★★

Rated 4.9 out of 5 from 276 verified Google reviews

The results from my PicoSure treatment have been incredible. My pigmentation has faded significantly and my skin looks clearer and more even than it has in years. Highly recommend Dr Joney and the whole team.

I had a course of PicoSure sessions for sun damage and the improvement is remarkable. The treatment was comfortable and the staff were professional throughout. I will definitely be returning.

Dr De Souza is exceptional. My skin tone is so much more even after PicoSure and the results keep improving. I cannot recommend this clinic highly enough.

Fantastic clinic. PicoSure has made a real difference to my skin texture and pigmentation. The aftercare advice was thorough and my results have been amazing.

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Where your journey begins 🤍

Welcome to Dr Joney De Souza Skin & Laser - this is the first thing you’ll see when you walk through our doors.

We know that coming in for an aesthetic treatment for the first time can feel daunting. Questions about what to expect, nerves about the treatment itself, uncertainty about whether it is the right decision, these are all completely normal, and we never take that lightly.

That is why the environment we have created here matters so much to us.

Our clinic is clean, safe, and held to the highest clinical standards, because when it comes to your skin and your health, that is non-negotiable. But we never wanted it to feel cold, clinical, or intimidating. We wanted it to feel like somewhere you could genuinely relax, from the very first moment you arrive.

That is why alongside everything you would expect from a leading skin and laser clinic, you will also find the kind of touches that make a space feel like somewhere you actually want to be. Picture frames. Mirrors. Magazines. Reed diffusers. The small details that take the edge off and remind you that while you are in expert hands, you are also somewhere that genuinely cares about how you feel, not just how your skin looks.

Because great results start with feeling comfortable enough to be yourself, ask your questions, and trust the people looking after you.

We cannot wait to welcome you, or welcome you back 🫶SkinPen Microneedling at Dr Joney De Souza Skin & Laser ✍️

SkinPen is the world’s first FDA-cleared microneedling device, and it is one of the most effective treatments we offer for improving skin texture, tone and overall quality.

Using a precise arrangement of fine needles, SkinPen creates thousands of controlled micro-injuries in the skin, triggering the body’s natural wound healing response. The result is a significant increase in collagen and elastin production - the two proteins responsible for keeping skin firm, smooth and youthful.

It is a treatment that addresses a wide range of concerns. Acne scarring, fine lines, enlarged pores, uneven texture, stretch marks and a general loss of skin quality. 

SkinPen works progressively to improve all of these with each session, delivering results that continue to develop for weeks after treatment.

Suitable for most skin types, with minimal downtime and no heat involved, making it a safe and effective option year round, including for darker skin tones that may not be suitable for certain laser treatments.

A course of three sessions is typically recommended for optimal results, spaced four to six weeks apart.

If you would like to find out whether SkinPen is right for your skin, book a consultation with us today 🤍Why PicoSure is Roma’s ultimate favorite treatment to perform...🌟

“I love working with the PicoSure Laser because it delivers incredible results with minimal downtime. From pigmentation and acne scars to skin rejuvenation and tattoo removal, it’s a versatile technology that helps clients achieve brighter, healthier-looking skin. Seeing their confidence grow after their treatment is the most rewarding part of my work.”

— Roma, Skin Therapist

Treat your skin to Roma’s top recommendation ! ✨Lip flip vs lip filler. Which one is right for you? Swipe through to find out 👉

Two very different treatments. Two very different results. And yet they are confused for each other constantly, so let us clear it up...

The lip flip
A lip flip uses a small amount of muscle-relaxing product placed into the muscle just above the upper lip. Rather than adding volume, it causes the upper lip to gently roll outward, creating the appearance of a fuller, more defined lip without any filler being used. The result is a subtle soft enhancement that works particularly well for anyone who feels their upper lip disappears when they smile, or who wants a more natural look without added volume. 

Lip filler
Lip filler uses hyaluronic acid to add volume, shape and definition to the lips. It can be used to enhance the overall size of the lips, define the lip border, correct asymmetry or restore volume that has been lost over time. The results are immediate and can be tailored precisely to what you are looking for - whether that is a subtle, natural enhancement or something more noticeable. 

So which one is for you? The best way to find out is by booking a consultation with us where your individual anatomy, goals and expectations can be properly assessed.

📍Marylebone, London | 020 7043 0748 📱The SPF market can feel overwhelming, and we completely understand why 👇

Too many options, too many textures, too many excuses. So let us make it simple.

We hear the same things all the time. It breaks me out. It leaves a white cast. It feels greasy. I just cannot be bothered. And honestly? Every single one of those concerns is valid. But in 2026, none of them are reasons not to wear SPF anymore.

The ZO Skin Health SPF range, which we stock here at Dr Joney De Souza Skin & Laser, has an option for every single skin type, concern and lifestyle. And we mean that.

💭Oily or acne-prone skin? The Sheer Fluid SPF 50 is lightweight, oil-free and non-comedogenic. No breakouts. No shine.

💭Want your SPF to double as a primer? The Sunscreen + Primer SPF 30 creates a flawless base for makeup in one step.

💭Need something for active days or the beach? The Daily Sheer SPF 50 is water resistant and suitable for all skin tones with zero white cast.

💭Want a little coverage too? The Smart Tone SPF 50 adapts to your skin tone for a subtle, skin-perfecting finish.

And for anyone who just cannot be bothered with reapplying? The Sunscreen + Powder SPF 30 is a brush-on powder that goes straight over your makeup, tops up your protection and controls shine at the same time. No fuss. No excuses.

There is an SPF for everyone. Come and find yours today 🤍

How can you find us?

Our clinic is located in Marylebone, London, in the heart of one of Central London’s most prestigious and renowned medical districts. Perfectly positioned for convenience and discretion, we are easily accessible from across the capital and beyond.

We welcome patients from Mayfair, Harley Street, Marylebone, Knightsbridge, Belgravia, Chelsea, Kensington, Fitzrovia and St John’s Wood, as well as international patients visiting London for specialist treatment.

Our location benefits from excellent transport connections, with close proximity to major Underground stations, mainline rail links and direct access to Heathrow, Gatwick and London City airports. Several secure parking facilities and convenient chauffeur drop-off points are available nearby, ensuring a seamless and comfortable visit.

Whether you are travelling from elsewhere in London, across the UK or internationally, our clinic offers a calm, private and exclusive setting in one of the world’s leading medical destinations.

Opening hours
Monday
9 am to 6 pm
Tuesday
9 am to 6 pm
Wednesday
9 am to 6 pm
Thursday
9 am to 6 pm
Friday
9 am to 6 pm
Saturday
Closed
Sunday
Closed
Dr Joney De Souza
49 Blandford St, London W1U 7HH
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