Doctor-led ZO Skin Health medical skincare in Marylebone, London. Prescription-strength programmes and facials for acne, pigmentation and ageing. From £110.
If your skincare shelf keeps growing but your skin never really changes, ZO Skin Health is built for you. It suits people dealing with acne and oily skin, uneven pigmentation, early or established signs of ageing, redness and skin that simply looks tired and dull. This is prescription-strength medical skincare, so it is matched to your skin after a proper assessment rather than picked off a shelf. Anyone serious about long-term skin health, and willing to follow a guided routine, gets the most from it.
ZO Skin Health is at its best building healthy, resilient skin, clearing congestion, evening out tone and softening early signs of ageing through a guided daily routine. It also works hand in hand with in-clinic care, so if your priority is deep lines, significant laxity or structural volume, we can combine it with treatments such as our skin boosters or a resurfacing plan, and we will map that out at your assessment.
ZO Skin Health is a medical-grade skincare range created by the dermatologist Dr Zein Obagi. It uses high-strength active ingredients, advanced delivery systems and bio-engineered complexes to work far deeper than over-the-counter products. At Dr Joney De Souza Clinic in Marylebone we prescribe it as the foundation of healthy, resilient skin, both on its own and as preparation and maintenance around other treatments.
Related treatments at Dr Joney De Souza: the ZO 3-step peel and HydraFacial.
Individual results vary from person to person. Treatment galleries are added as before-and-after photographs become available; Dr De Souza can show relevant examples during your consultation.
ZO treats the skin at a level standard products cannot reach. High-performance actives, advanced delivery systems and bio-engineered complexes work together to renew and strengthen the skin over time. Your practitioner prescribes a personalised programme after assessing your skin, then introduces each product in the right order so your skin builds tolerance and you avoid unnecessary irritation. In clinic, targeted ZO facials lift the results of your home routine and address specific concerns. The two together keep the skin healthy and resilient in a way skincare alone rarely manages.
Your ZO journey begins with a skin consultation at Dr Joney De Souza Clinic in Marylebone. Your practitioner assesses your skin and your main concerns, whether that is acne, pigmentation, ageing or redness. ZO is prescription-strength medical skincare, so this assessment is essential rather than optional. You leave with a clear, personalised plan and an understanding of how the range can help.
Your practitioner then prescribes a personalised ZO programme using clinical-strength formulations matched to your concern. The right products are selected and each one is explained so you understand what it does. The programme is tailored to your skin rather than taken off a shelf. You know exactly what you are using and why.
ZO is powerful medical skincare, so the products are introduced in the right order and at a sensible pace. This builds your skin’s tolerance and avoids unnecessary irritation. Your practitioner guides you through how and when to use each step. This careful introduction is central to getting the best result.
Alongside your home routine, targeted ZO facials boost your results and address specific concerns such as oil control, brightening or redness. Each facial can be taken as a single treatment or a course. They complement the products you use at home and treat the skin at a deeper level than skincare alone.
As your skin improves, the clinic reviews your progress and adjusts your programme accordingly. ZO also prepares and maintains your skin around other in-clinic treatments. This ongoing, doctor-led guidance keeps your routine working as your skin changes, so you are supported throughout rather than left to guess.
Improvements build gradually over the following weeks as the skin renews and strengthens. With a maintained routine, ZO supports genuine, long-term skin health rather than a short-term fix. Your practitioner recommends how to sustain your results and sets realistic expectations at your consultation.
From your first consultation through to your results, here is what to expect at our Marylebone clinic. Carried out by Dr Joney De Souza or a member of our clinical team. Your consultation is with Dr Joney De Souza or Dr Mattia Parducci.
Your ZO Skin Health journey begins with a consultation at Dr Joney De Souza Clinic in Marylebone. Your practitioner assesses your concern, confirms ZO Skin Health is right for you and plans your treatment. They explain what to expect and answer any questions. In most cases you need no special preparation, and you leave with a clear, personalised plan.
On the day, the area is prepared and your practitioner carries out your ZO Skin Health treatment, which typically takes 30-45 mins. Most patients find it comfortable and straightforward. The area is worked through methodically for an even, natural result, and you can return to your day straight afterwards.
Afterwards, any mild redness or tenderness settles quickly, with little to no downtime. Results build gradually over weeks as your skin responds, looking natural rather than sudden. Your practitioner gives you full aftercare guidance before you leave and advises on maintenance to sustain your result.
Medical skincare works best when a doctor prescribes and guides it, and at Dr Joney De Souza Clinic in Marylebone that is exactly how ZO is delivered. Your skin is assessed, a personalised programme is built, and it is adjusted as your skin improves. ZO is also integrated with your in-clinic treatments so everything works together toward the same result.
This considered, doctor-led approach reflects how Dr De Souza practises across the board.
My ‘less is more’ approach has become the mainstay of my practice and clients appreciate that they will have natural looking results. Dr Joney De Souza, The Sybarite
That philosophy is what turns good skincare into genuine, lasting results, guided by a doctor rather than left to guesswork.
ZO Skin Health facials are individually priced and available as single treatments or courses, while home programmes are tailored to your routine and confirmed at consultation. Every plan begins with a skin assessment so the products and facials suit your concern. Your practitioner agrees your plan and cost with you before you begin.
| ZO Facial | Single (£) | Course (£) |
|---|---|---|
Acne & Oil Control | 175 | 475 |
Skin Brightening | 195 | 525 |
Redness | 160 | 425 |
Restorative Peel | 140 | 370 |
Hand Renewal | 110 | 290 |
The ZO 3-Step Peel is a medical-grade in-clinic peel that pairs well with a ZO home routine for a deeper improvement in tone and texture. Many patients combine the two, using the home programme to prepare and maintain the skin around the peel. If you want to step up your skin renewal, it is well worth exploring.
ZO Skin Health raises common questions around what it treats, whether you need a consultation and how it works with other treatments. The answers below cover what patients most often ask.
Our patients return to us year after year for natural, precise results. Every review reflects our commitment to clinical excellence, patient safety and a personalised approach to aesthetic care.
Had my second session of PRP with micro needling today and I am so far very happy with my results. Dr De Souza is just the kindest man who really has the best intentions for you.
I highly recommend Dr. Joney and his clinic. I have been his patient for many years and he is definitely one of the best. His work is natural and subtle, he always puts the patient’s interest first and will never try to upsell unnecessary treatments.
Dr Joney is the most wonderful Dr, kind and caring and highly experienced. I feel safe in his care and trust his opinion 100%.
