PRP Treatment in Marylebone, London

PRP treatment in Marylebone, London. Doctor-led platelet rich plasma to stimulate collagen and restore radiance. From £490. Book at Dr Joney De Souza Clinic.

PRP Treatment London

Regenerative treatment using your own blood to stimulate collagen, improve skin texture and restore natural radiance. Doctor-led. No synthetic materials. Minimal downtime.

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No. of treatments
Initially a course of 3 treatments spaced three months apart
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Procedure time
60 minutes
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Back to work
2 days
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Duration of results
Maximum results after 6 months but skin continues to improve over time.
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Anaesthetic
Topical cream
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Sensitivity period
24-72 hours
Price From
£490

Who Is PRP Treatment For?

You have started to notice your skin looking flatter than it used to. The glow has faded, fine lines are settling in around the eyes and mouth, and no amount of skincare quite brings back that lit-from-within quality. PRP treatment in London is built for exactly this moment, and most of our Marylebone patients sit somewhere between their late twenties and early sixties when they book it. Age is only part of the picture, though. What matters more is that you want a real, lasting improvement in the condition of your skin rather than a quick surface fix.

Skin Concerns PRP Addresses Well

PRP facial treatment tends to suit patients dealing with one or more of the following:

  • Fine lines and early wrinkles around the eyes, mouth and forehead
  • Dull, uneven or sun-damaged skin tone
  • Visible loss of firmness across the lower face or neck
  • Enlarged pores and rough surface texture
  • Dark circles and thinning skin beneath the eyes
  • Decolletage skin that appears crepey or sun-damaged
  • Mild to moderate acne scarring
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What Is PRP Treatment?

PRP stands for Platelet Rich Plasma. It is a regenerative injectable that uses a concentrated preparation of your own plasma to stimulate collagen production, improve skin texture and bring back natural radiance.

The process is simple. A small blood sample is taken at the clinic and spun in a centrifuge to isolate the platelet-rich fraction. That concentrated preparation is rich in growth factors, and once injected into targeted areas of the face it wakes up the skin’s own repair and renewal response.

New collagen forms, circulation improves, and over the following weeks the skin becomes firmer, smoother and more luminous. The look is natural, and it builds gradually over four to eight weeks after each session rather than appearing overnight.

PRP Before & After Results in Marylebone

Our PRP patients typically notice gradual improvement in skin radiance, texture and firmness over 4 to 8 weeks following their first session. Results continue to develop as collagen builds across a course of treatment, creating a naturally refreshed appearance without any obvious signs of injectable treatment.

Before
After
Before
After

How Does PRP Treatment Work?

PRP works by concentrating the growth factors that are naturally present in your blood and delivering them into the skin at depth. That triggers a controlled regenerative response, stimulating collagen production, tissue repair and better microcirculation across the area being treated. In other words, your own biology does the work, prompted by a preparation made from a small sample of your blood.

Key Benefits of PRP Treatment

  • Stimulates new collagen and elastin using nothing but your own biology
  • Progressively improves skin firmness, texture and radiance
  • Reduces fine lines and early wrinkles over weeks without surgery
  • Brightens dull, uneven or sun-damaged skin tone
  • Suitable for the face, neck and decolletage in a single session
  • No risk of allergic reaction, as treatment uses only your own blood
  • Minimal downtime, with most patients back to normal activities within 24 hours
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Step 1: Blood draw and preparation

Your practitioner draws a small blood sample from your arm before treatment begins. The volume is similar to a standard blood test and takes only a few minutes. It is a straightforward step, and most patients find it very comfortable.

Step 2: Centrifuge processing

The sample then goes into our centrifuge and spins at high speed. This separates the blood into its layers, concentrating the platelets and growth factors into a highly active plasma preparation. The result is a consistent, high quality preparation ready for injection.

Step 3: Topical anaesthetic

Once the plasma is ready, a topical numbing cream is applied across the treatment area and left to take full effect before anything else happens. Most patients find the injection phase very manageable as a result, and discomfort during PRP injections at our London clinic is minimal.

Step 4: Precise injection

The concentrated PRP is then injected into targeted areas using fine needles. The technique changes by area and concern, with extra precision applied to delicate zones such as the under-eye area or around the mouth. Each session is tailored to your specific skin goals rather than following a fixed protocol.

Step 5: Immediate aftercare

After the injections, your practitioner reviews the treated area and gives you specific aftercare guidance. Some redness or minor swelling is normal and usually clears within 24 to 48 hours. Most patients return to their normal activities the following day.

Step 6: Regeneration over weeks

Over the following four to eight weeks, the growth factors activate the skin’s collagen-producing cells. New blood vessel formation improves microcirculation, gradually brightening and firming the skin as the regenerative process continues. The full benefit of a course usually becomes visible by the three-month mark.

Your PRP Treatment Journey

First-Time Patients

Your PRP journey at Dr Joney De Souza Clinic starts with a full medical consultation. During this appointment, your practitioner reviews your skin health, medical history and treatment goals to confirm suitability and recommend the right number of sessions. A course of two to three sessions spaced four to six weeks apart tends to produce the strongest cumulative result.

If you are new to regenerative treatment, PRP is one of the easiest places to start. There is no synthetic material, no significant recovery period, and results that build naturally over weeks rather than landing all at once.

Ongoing Patients

Once you have completed an initial course, a maintenance session once or twice a year usually sustains what you have achieved. Many patients go on to pair PRP with complementary treatments such as SkinPen microneedling, polynucleotides or skin boosters as their goals evolve.

Your skin is reviewed at each appointment and the approach is adjusted as your skin changes and matures over time.

Before treatment

As advised at consultation, avoid blood-thinning medications and alcohol in the days before your appointment where it is medically appropriate to do so. Staying well hydrated helps ensure a good quality blood draw on the day. Our team will contact you beforehand with any specific preparation instructions relevant to your medical history.

During treatment

PRP treatment takes roughly 45 to 60 minutes in total. Once the topical anaesthetic has taken full effect, your practitioner begins the injection sequence. Most patients find the experience very manageable and leave the clinic the same day.

After treatment

Mild redness, swelling or small injection marks are common in the 24 to 48 hours after treatment, and they usually settle without any specific intervention. We advise avoiding strenuous exercise, saunas and direct sun exposure during this period. The skin then heals more efficiently and the regenerative process develops undisturbed.

Why Dr Joney De Souza Clinic?

At Dr Joney De Souza Clinic, PRP is delivered by practitioners with advanced training in regenerative injectables and a thorough grasp of facial anatomy. Every patient completes a full medical consultation before treatment begins, which confirms suitability, establishes your skin goals and lets us tailor the session to you rather than reaching for a fixed protocol.

Dr Joney De Souza’s philosophy shapes how every treatment here is approached.

My ‘less is more’ approach has become the mainstay of my practice and clients appreciate that they will have natural looking results.

Dr Joney De Souza, The Sybarite

Rated 4.9 From Over 272 Google Reviews

Our patients come back year after year for results that are natural, balanced and genuinely lasting. Our doctors have delivered PRP across thousands of patient sessions, refining both the injection technique and the patient journey around real clinical outcomes rather than passing trends.

A Medical Standard of Care

Every PRP session at our clinic uses CE-certified preparation equipment, so you get a consistently high quality plasma preparation at each visit. Treatment takes place in a medically supervised environment, with full aftercare guidance provided before you leave.

  • Doctor-led aesthetic clinic in Marylebone, central London
  • Full medical consultation before every course of treatment
  • CE-certified PRP preparation equipment used at every session
  • Rated 4.9 from over 272 verified Google reviews
  • Tailored treatment plans reviewed and adjusted at each visit

It is an approach rooted in skin longevity, using your own growth factors to support the skin’s natural repair and gently reinforce its own structure, so skin quality is looked after for the years ahead.

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PRP Treatment Pricing

PRP at Dr Joney De Souza Clinic is priced by the number of areas treated in a single session. Treatment can be applied to the face, neck or decolletage on its own, or across two areas in the same appointment for a more comprehensive regenerative result.

Which Areas Can Be Treated?

One-area treatment is the most common starting point and usually covers the full face. If you have visible concerns across the neck or decolletage as well, combining areas in a single session tends to make sense. Treating two areas together works out more cost-effective than separate bookings, and it gives a more consistent regenerative result across a wider surface.

PRP treatment pricing

TreatmentSingleCourse of 2

Face, Neck or Décolletage

£490

£830

2 Areas

£660

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Final pricing may vary based on your treatment plan and clinical assessment.
Not sure? WhatsApp us for advice

Enhance Your Results with SkinPen Microneedling

SkinPen is an FDA-cleared microneedling device and one of the most clinically validated tools available for skin renewal. At Dr Joney De Souza Clinic, SkinPen is often combined with PRP in a single session for patients who want to tackle texture, scarring and early ageing at the same time. The micro-channels SkinPen creates let PRP reach deeper layers of the skin than topical application manages on its own.

The combined treatment produces a stronger regenerative response than either approach delivers alone. It suits patients with acne scarring, enlarged pores or uneven skin tone especially well, where surface refinement and deeper collagen stimulation are both needed. Results also tend to appear more quickly after a combined session than after PRP alone. You can read more about the pairing on our PRP and SkinPen microneedling page.

The session takes roughly 60 to 90 minutes and recovery is comparable to standalone PRP. Suitability depends on your skin concern and current condition. If you would like advice on whether SkinPen with PRP is right for you, WhatsApp our team for a quick recommendation before booking.

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Frequently Asked Questions

Below are the questions patients most commonly ask about PRP treatment for the face in London. For anything not covered here, WhatsApp our team directly for a quick answer.

What is PRP Treatment

PRP treatment for the face uses a concentrated preparation of your own blood to stimulate collagen production, improve skin texture and restore natural radiance. A small blood sample is drawn, processed to isolate the platelet-rich plasma, and injected into targeted areas of the face. It uses only your own blood, so there is no risk of an allergic reaction and no synthetic material involved. Results develop progressively over four to eight weeks as the skin’s repair response takes hold.

When will I see results from PRP treatment?

Most patients notice early improvements in skin texture and radiance within two to four weeks of their first session. Firmer, smoother skin with a more even tone typically becomes visible at six to eight weeks. The full benefit of a course is usually apparent by three months.

How long does PRP treatment last?

A course of two to three sessions typically delivers results lasting twelve to eighteen months, though longevity depends on your age, skin condition and lifestyle. A maintenance session once or twice a year is usually enough to sustain the improvements you have achieved.

How many PRP treatment sessions do I need?

Most patients benefit from a course of two to three sessions, spaced four to six weeks apart. Each session builds on the regenerative response triggered by the last, producing a cumulative improvement in skin quality, firmness and radiance. Some patients with more pronounced concerns benefit from additional sessions as part of a longer plan, which your practitioner discusses at consultation.

Is PRP treatment good for dark circles and under-eye bags?

PRP is one of the more effective options for the under-eye area, improving microcirculation, stimulating collagen and reducing the appearance of dark circles caused by skin thinning. The skin here is particularly delicate, so results develop more gradually than on other areas of the face. Multiple sessions are usually recommended for the best outcome in this zone.

Is PRP treatment good for skin texture and enlarged pores?

Yes. PRP stimulates collagen and fibroblast activity, which progressively refines skin texture, reduces the appearance of enlarged pores and smooths surface irregularities. Most patients notice a meaningful improvement in texture and skin quality after a course of two to three sessions. It works particularly well when combined with microneedling.

Is PRP treatment good for fine lines and early wrinkles?

PRP is well suited to fine lines and early wrinkles, particularly around the eyes, mouth and forehead where skin is thinner and more prone to early ageing. By rebuilding the collagen framework beneath the surface, PRP softens these lines progressively over weeks. It is not a replacement for anti-wrinkle injections, but it complements them well, addressing the underlying tissue quality rather than just the surface movement.

Is PRP treatment good for dull or uneven skin tone?

PRP improves radiance and tone by encouraging the formation of new blood vessels, which enhances microcirculation and gives the skin a healthier, more luminous look. Patients with dull, tired or sun-damaged skin consistently report a noticeable improvement in overall glow and clarity after a course of treatment.

Is PRP treatment suitable for all skin types?

PRP suits most skin types and tones well because it works through your own biology rather than introducing a synthetic substance. Since the preparation draws entirely from your own blood, there is no risk of an adverse reaction related to skin type. Suitability is always assessed individually at consultation, taking your medical history and current skin condition into account.

Is PRP treatment good for acne scarring?

PRP supports the remodelling of scar tissue by stimulating collagen production and tissue regeneration in the affected areas. It works best on mild to moderate atrophic scarring rather than deep or ice-pick scars. For more significant acne scarring, your practitioner may recommend combining PRP with microneedling, which strengthens the regenerative response and improves surface texture at the same time.

Can PRP treat the neck and decolletage as well as the face?

Yes. PRP can cover the neck and decolletage in the same session as the face, or as a standalone treatment if those are your main concerns. Treating two areas together works out more cost-effective than separate bookings and gives a more consistent regenerative result across a wider surface.

PRP vs Other Treatments

PRP is one of several regenerative treatments available at Dr Joney De Souza Clinic in London. The questions below cover how it compares to the alternatives and what to weigh up when choosing the right approach for your skin.

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Read our reviews

Our patients return to us year after year for natural, balanced results. Every review reflects our commitment to precision, safety and a personalised approach to aesthetic care.

I’m absolutely thrilled with the results of my HydraFacial at Dr. Joney De. Suza’s clinic. I was so impressed that I’ve already booked my next appointment and can’t wait to make it a regular part of my routine. I’ve also been raving about it to all my girlfriends. Best, Trisha S
I recently had the “HydraFacial” treatment and I can honestly say it was one of the best facial treatments I have ever had. It was my first time to the clinic after many recommendations. The space is beautiful and calming. The team made me feel so welcome and talked me through every step of the treatment which was carried out using only the best products and equipment. I left the clinic with the most glowing skin and I could clearly see the results even after only one treatment. I could not recommend this clinic enough. Thank you again!
Sarah McGovern
Sarah McGovern
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I recently had a HydraFacial with Roma and the results have been nothing short of amazing. I was impressed by the modern, pristine clinic and the warm, welcoming staff. Roma, the aesthetician, was professional and knowledgeable. She took the time to understand my skincare concerns and explained the HydraFacial process in detail. The treatment itself was fantastic and over the next few days my skin was noticeably smoother and more even toned. She also provided sound aftercare advice, telling me how I can reduce my overall skincare budget at home whilst improving results, so no upsell just solid pro experience on what works best.
Sarah Sabner
Sarah Sabner
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I genuinely wouldn’t trust anyone else with my skin. Dr Joney de Souza remains my top recommendation for anyone seeking expert aesthetic care in London. He has a calm, professional manner and always takes the time to truly listen and understand what you’re hoping to achieve. His approach is natural and refined, you always leave looking like the best version of yourself, never overdone. The clinic is a beautiful, welcoming space in the heart of London, and the entire team is warm, knowledgeable, and highly professional. Dr Joney’s expertise and eye for detail are truly exceptional, and the results speak for themselves.
Daniele Bernardinetti
Daniele Bernardinetti
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Kind words that made our day 🤍

We were so touched to receive this lovely feedback from a recent client following her PicoSure face treatment with Roma - this one’s for David, Roma, and Dr Joney.

“From the moment I arrived, David and Roma made me feel so welcome and completely at ease. Roma was caring, professional, and took the time to explain the treatment thoroughly, making sure I felt comfortable and reassured throughout. Even after just one session, my skin already feels smoother and looks much more refreshed.”

Moments like this are exactly why we do what we do. It’s not just about the results (although we’re so pleased with how her skin is already responding!), it’s about making every client feel genuinely cared for from the second they walk through the door.

Thank you to our amazing client for such kind words, and to David, Roma, and Dr Joney for the warmth and care you bring to every single appointment 🫶HydraFacial: the secret to that red-carpet glow ✨

Ever wondered what actually happens during a HydraFacial? Here’s a look inside the treatment, step by step, at Dr Joney De Souza.

It begins with a deep cleanse and exfoliation to clear away impurities and prepare the skin, followed by gentle extractions that refine congestion with complete comfort and precision. 

From there, targeted serums and boosters are infused into the skin, tailored entirely to your individual needs, before LED light therapy supports the skin’s long-term health and renewal. 

The treatment finishes with an antioxidant infusion, sealing in radiance for that lit-from-within finish.

This particular treatment was our Deluxe HydraFacial, though for those wanting to elevate the experience further, our Platinum HydraFacial also includes lymphatic drainage, perfect for extra de-puffing and detoxification alongside all the usual glow-boosting benefits.

The result is skin that looks cleansed, replenished, and effortlessly glowing, delivered with the precision and care that defines every treatment here.

📍 Marylebone, London | 020 7043 0748 📱Sculptra vs Juläine: which biostimulator is right for you? 💭

Both Sculptra and Juläine are poly-L-lactic acid (PLLA) biostimulators - meaning rather than simply adding volume, they work by encouraging your skin to produce its own natural collagen over time, for results that look and feel truly you.

Sculptra is the original PLLA injectable, with a long-established track record for stimulating collagen and improving skin structure and firmness gradually over several months, with results that can last up to two years.

Juläine is a newer generation PLLA treatment, using more uniform, highly purified microspheres engineered to mix more evenly, which can help reduce inflammation caused by treatment. Like Sculptra, results build gradually, with visible improvements from a few weeks in and full effects developing over a few months. 

Both are excellent options for restoring facial volume, improving skin quality, and softening lines. The right choice really depends on your skin, goals, and what your practitioner recommends for you.

Not sure which is best suited to your skin and goals? Get in touch with us today to book your consultation.

📍Marylebone, London | 020 7043 0748 📱Product Spotlight | Daily Power Defense ✨

ZO Skin Health’s Daily Power Defense is one of those products that quietly does a lot of the heavy lifting in a skincare routine, and it’s become a firm favourite of ours here at the clinic.

Formulated with Vitamins A and E, it helps protect the skin against environmental damage and free radicals, while supporting barrier restoration and long-lasting hydration.
Over time, this can mean fewer visible signs of premature ageing and a stronger, more resilient complexion.

It’s a lightweight daily step, but one that adds up - the kind of product that supports your skin quietly in the background, day after day.

If you’re curious whether it fits into your routine, drop us a DM, or ask at your next appointment 📅

How can you find us?

Our clinic is located in Marylebone, London, in the heart of one of Central London’s most prestigious and renowned medical districts. Perfectly positioned for convenience and discretion, we are easily accessible from across the capital and beyond.

We welcome patients from Mayfair, Harley Street, Marylebone, Knightsbridge, Belgravia, Chelsea, Kensington, Fitzrovia and St John’s Wood, as well as international patients visiting London for specialist treatment.

Our location benefits from excellent transport connections, with close proximity to major Underground stations, mainline rail links and direct access to Heathrow, Gatwick and London City airports. Several secure parking facilities and convenient chauffeur drop-off points are available nearby, ensuring a seamless and comfortable visit.

Whether you are travelling from elsewhere in London, across the UK or internationally, our clinic offers a calm, private and exclusive setting in one of the world’s leading medical destinations.

Opening hours
Monday
9 am to 6 pm
Tuesday
9 am to 6 pm
Wednesday
9 am to 6 pm
Thursday
9 am to 6 pm
Friday
9 am to 6 pm
Saturday
Closed
Sunday
Closed
Dr Joney De Souza
49 Blandford St, London W1U 7HH
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