
Platelet Rich Plasma therapy uses your body’s own growth factors to repair, rejuvenate and revitalise the skin, improving texture, firmness and overall radiance.
Regenerative treatment using your own blood to stimulate collagen, improve skin texture and restore natural radiance. Doctor-led. No synthetic materials. Minimal downtime.
In most cases, PRP treatment in London suits patients in their late twenties to early sixties who want a genuine, lasting improvement in skin quality. However, the decision does not depend on age alone. Specifically, patients arrive at our Marylebone clinic with concerns about overall skin condition, early ageing or loss of radiance, rather than a single isolated feature.
In practice, PRP facial treatment is particularly effective for patients with one or more of the following concerns:
Because PRP uses only your own blood, there is no risk of allergic reaction. However, treatment is not appropriate for patients who are pregnant, who have active skin infections at the treatment site, or who cannot safely pause blood-thinning medication. Additionally, Dr De Souza confirms suitability at consultation before any treatment begins.
Specifically, PRP stands for Platelet Rich Plasma. In other words, it is a regenerative injectable that uses a highly concentrated preparation of your own plasma to stimulate collagen production, improve skin texture and restore natural radiance.
In practice, Dr De Souza draws a small blood sample at the clinic and processes it in a centrifuge to isolate the platelet-rich fraction. Consequently, the concentrated preparation carries a high level of growth factors that, once injected into targeted areas of the face, trigger the skin’s natural repair and renewal response.
Subsequently, new collagen forms and circulation improves. As a result, the skin progressively becomes firmer, smoother and more luminous. Overall, results are natural in appearance and develop gradually over four to eight weeks after each session.
In essence, PRP works by concentrating the growth factors naturally present in your blood and delivering them directly into the skin at depth. As a result, this triggers a controlled regenerative response, stimulating collagen production, tissue repair and improved microcirculation across the treated area.
Before treatment begins, Dr De Souza draws a small blood sample from your arm. The volume is similar to a standard blood test and takes only a few minutes. Additionally, the process is straightforward and most patients find it very comfortable.
Next, the sample goes into our centrifuge system and spins at high speed. This separates the blood into its component layers, concentrating the platelets and growth factors into a highly active plasma preparation. Consequently, the result is a consistent, high quality preparation ready for injection.
Once the plasma is ready, Dr De Souza applies a topical numbing cream across the treatment area. He allows this to take full effect before proceeding, so most patients find the injection phase very manageable. Overall, discomfort during PRP injections in London at our clinic is minimal.
He then injects the concentrated PRP into targeted areas using fine needles. In practice, the technique varies by area and concern, with greater precision applied to delicate zones such as the under-eye area or around the mouth. As a result, each session is tailored to your specific skin goals rather than following a standard protocol.
After the injections are complete, Dr De Souza reviews the treated area and provides specific aftercare guidance. Some redness or minor swelling is normal and typically clears within 24 to 48 hours. Additionally, most patients return to their normal activities the following day.
Over the following four to eight weeks, growth factors activate the skin’s collagen-producing cells. Furthermore, new blood vessel formation improves microcirculation, gradually brightening and firming the skin as the regenerative process continues. In most cases, the full benefit of a course becomes visible by the three-month mark.
PRP at Dr Joney De Souza Clinic begins with a full medical consultation. During this appointment, Dr De Souza reviews your skin health, medical history and treatment goals to confirm suitability and recommend the right number of sessions. In most cases, a course of two to three sessions spaced four to six weeks apart produces the strongest cumulative result.
For patients new to regenerative treatment, PRP is one of the most accessible starting points. Specifically, it involves no synthetic material, no significant recovery period and results that build naturally over weeks rather than appearing overnight.
For patients who have completed an initial course, a maintenance session once or twice a year typically sustains the improvements achieved. Over time, many patients choose to combine PRP with complementary treatments such as Microneedling, polynucleotides or skin boosters as their skin goals evolve.
Additionally, Dr De Souza reviews your skin at each appointment and adjusts the treatment approach as your skin changes and matures.
As advised at consultation, avoid blood-thinning medications and alcohol in the days before your appointment where medically appropriate. In practice, staying well hydrated helps ensure a good quality blood draw on the day. Additionally, Dr De Souza’s team will contact you beforehand with any specific preparation instructions relevant to your medical history.
PRP treatment takes approximately 45 to 60 minutes in total. Once the topical anaesthetic takes full effect, Dr De Souza begins the injection sequence. Overall, most patients find the experience very manageable and leave the clinic the same day.
Mild redness, swelling or small injection marks are common in the 24 to 48 hours following treatment. In most cases, these resolve without any specific intervention. Additionally, we advise avoiding strenuous exercise, saunas and direct sun exposure during this period. As a result, the skin heals more efficiently and the regenerative process develops undisturbed.
At Dr Joney De Souza Clinic, PRP is delivered by practitioners with advanced training in regenerative injectables and a thorough understanding of facial anatomy. As a standard, every patient completes a full medical consultation before treatment begins. In practice, this step confirms suitability, establishes your skin goals and allows Dr De Souza to tailor the session individually rather than applying a standard protocol.
Indeed, our patients return to us year after year for results that are natural, balanced and genuinely lasting. Moreover, Dr De Souza has delivered PRP treatment across thousands of patient sessions, refining both the injection technique and the patient journey based on clinical outcomes rather than trends.
Furthermore, every PRP session at our clinic uses CE-certified preparation equipment, producing a consistently high quality plasma preparation at each visit. As a result, treatment takes place in a medically supervised environment, with full aftercare guidance provided before you leave.
PRP at Dr Joney De Souza Clinic is priced by the number of areas treated in a single session. Treatment can be applied to the face, neck or decolletage individually, or across two areas in the same appointment for a more comprehensive regenerative result.
One-area treatment is the most common starting point, typically covering the full face. However, patients with visible concerns across the neck or decolletage benefit from combining areas in a single session. In practice, treating two areas together is more cost-effective than separate bookings and ensures a more consistent regenerative result across a wider surface.
| Treatment | Single | Course of 2 |
|---|---|---|
Face, Neck or Décolletage | £490 | £830 |
2 Areas | £660 | — |
SkinPen is an FDA-cleared microneedling device and one of the most clinically validated tools available for skin renewal. At Dr Joney De Souza Clinic, SkinPen is frequently combined with PRP in a single session for patients who want to address texture, scarring and early ageing at the same time. In practice, the micro-channels SkinPen creates allow PRP to reach deeper layers of the skin than topical application achieves alone.
As a result, the combined treatment produces a stronger regenerative response than either approach delivers independently. It is particularly well suited to patients with acne scarring, enlarged pores, or uneven skin tone where surface refinement and deeper collagen stimulation are both needed. Furthermore, results tend to appear more quickly after a combined session than after PRP alone.
Overall, the session takes approximately 60 to 90 minutes and recovery is comparable to standalone PRP. However, individual suitability depends on your skin concern and current condition. If you would like advice on whether SkinPen with PRP is right for you, WhatsApp Dr De Souza’s team for a quick recommendation before booking.

Below are the questions patients most commonly ask about PRP London treatment for the face. For anything not covered here, WhatsApp our team directly for a quick answer.
Specifically, PRP treatment for the face uses a concentrated preparation of your own blood to stimulate collagen production, improve skin texture and restore natural radiance. In practice, Dr De Souza draws a small blood sample, processes it to isolate the platelet-rich plasma, and injects it into targeted areas of the face. Because treatment uses only your own blood, there is no risk of allergic reaction and no synthetic material involved. Overall, results develop progressively over four to eight weeks as the skin’s repair response takes hold.
In most cases, patients notice early improvements in skin texture and radiance within two to four weeks of their first session. Furthermore, firmer and smoother skin with a more even tone typically becomes visible at six to eight weeks. Overall, the full benefit of a course is usually apparent by three months.
In practice, a course of two to three sessions typically delivers results lasting twelve to eighteen months. However, longevity depends on age, skin condition and lifestyle. In most cases, a maintenance session once or twice a year is enough to sustain the improvements achieved.
In most cases, patients benefit from a course of two to three sessions, spaced four to six weeks apart. Additionally, each session builds on the regenerative response triggered by the last, producing a cumulative improvement in skin quality, firmness and radiance. However, some patients with more pronounced concerns may benefit from additional sessions as part of a longer plan, which Dr De Souza discusses at consultation.
In fact, PRP is one of the more effective options for the under-eye area, improving microcirculation, stimulating collagen and reducing the appearance of dark circles caused by skin thinning. However, the skin here is particularly delicate, so results develop more gradually than on other areas of the face. As a result, multiple sessions are usually recommended for best outcomes in this zone.
Yes. In practice, PRP stimulates collagen and fibroblast activity, which progressively refines skin texture, reduces the appearance of enlarged pores and smooths surface irregularities. As a result, most patients notice a meaningful improvement in texture and skin quality following a course of two to three sessions. Furthermore, it works particularly well when combined with Microneedling.
Overall, PRP is well suited to fine lines and early wrinkles, particularly around the eyes, mouth and forehead where skin is thinner and more prone to early ageing. Specifically, by rebuilding the collagen framework beneath the skin’s surface, PRP softens these lines progressively over weeks. However, it is not a replacement for anti-wrinkle injections but complements them well, addressing the underlying tissue quality rather than just the surface movement.
As a result of stimulating angiogenesis, PRP improves skin radiance and tone by encouraging the formation of new blood vessels, which enhances microcirculation and gives the skin a healthier, more luminous appearance. Additionally, patients with dull, tired or sun-damaged skin consistently report a noticeable improvement in overall glow and clarity following a course of treatment.
In general, PRP is well suited to most skin types and tones because it works through your own biology rather than introducing a synthetic substance. Specifically, because the preparation draws entirely from your own blood, there is no risk of an adverse reaction related to skin type. However, suitability is always assessed individually at consultation, taking into account your medical history and current skin condition.
In practice, PRP supports the remodelling of scar tissue by stimulating collagen production and tissue regeneration in affected areas. However, it works best on mild to moderate atrophic scarring rather than deep or ice-pick scars. For more significant acne scarring, Dr De Souza may recommend combining PRP with Microneedling, which enhances the regenerative response and improves surface texture simultaneously.
Yes. In practice, PRP covers the neck and decolletage in the same session as the face, or as a standalone treatment for patients whose primary concerns are in these areas. Furthermore, treating two areas together is more cost-effective than separate bookings and ensures a more consistent regenerative result across a wider surface.
PRP is one of several regenerative treatments available at Dr Joney De Souza Clinic in London. The questions below address how it compares to alternatives and what to consider when choosing the right approach for your skin.
In practice, PRP and anti-wrinkle injections work in entirely different ways and are not in competition with each other. Specifically, anti-wrinkle injections relax the muscles that cause dynamic lines and deliver an immediate, visible result. However, PRP works at a deeper biological level, stimulating collagen and tissue renewal over weeks. As a result, many patients benefit from both, with anti-wrinkle injections addressing movement-related lines and PRP improving the overall quality of the skin beneath.
Yes, and in many cases combining PRP with other treatments produces a stronger result than either alone. In practice, PRP is frequently combined with Microneedling with SkinPen, where the micro-channels enhance PRP absorption and amplify collagen stimulation. Additionally, it works well alongside polynucleotides and skin boosters as part of a broader regenerative plan. Dr De Souza discusses combination options at consultation.
In fact, PRP is one of the safest treatments available in aesthetic medicine because it uses nothing but your own blood. There is no synthetic material, no donor tissue and no risk of allergic reaction. Furthermore, CE-certified preparation equipment is used at every session, producing a consistently high quality plasma preparation. As with any injectable treatment, there is a small risk of bruising or temporary redness, which typically resolves within 48 hours.
In practice, the quality of PRP injections London patients receive depends heavily on two things: the preparation system used and the skill of the person delivering it. At Dr Joney De Souza Clinic, Dr De Souza performs or directly oversees every PRP treatment. Additionally, he assesses every patient for suitability before treatment begins, and refines the injection technique to each individual’s anatomy rather than applying a standard protocol.
For the right patient, PRP is one of the most effective regenerative treatments available, with a strong safety profile, no synthetic material and minimal downtime. However, results are gradual and natural looking rather than immediate. As with any treatment, outcomes vary between individuals, which is why a thorough consultation with Dr De Souza is always the first step before committing to a course.
Dr De Souza applies a topical numbing cream beforehand, so most patients find the treatment very manageable. You may feel mild pressure or a brief sting during the injections. Afterwards, some redness and minor swelling are normal and typically clear within 24 to 48 hours. Additionally, most patients return to their normal activities the following day.
At our PRP London clinic in Marylebone, PRP starts from £490 for one area in a single session, with a course of two from £830. Additionally, two-area treatment is £660 per session. However, final pricing depends on the number of areas treated and any additional treatments included in your plan. Dr De Souza confirms pricing at consultation.
For patients wanting a genuine, lasting improvement in skin quality, PRP represents strong value compared to treatments that require more frequent repetition or carry higher risks. In practice, the biological improvements in collagen, texture and radiance that a course of PRP produces typically hold for twelve to eighteen months. However, individual results vary, which is why Dr De Souza sets realistic expectations at consultation.
In practice, all three are regenerative injectables but they work differently. Specifically, PRP uses your own growth factors to stimulate collagen and tissue repair. However, Profhilo uses a high concentration of hyaluronic acid to remodel the skin and restore deep hydration, while polynucleotides use DNA fragments to repair and strengthen the skin at a cellular level. In most cases, these treatments work best in combination rather than as alternatives, since each targets a different aspect of skin ageing.
In practice, Microneedling with SkinPen creates controlled micro-channels in the skin to trigger collagen production, and combining it with PRP enhances the regenerative response significantly. Furthermore, exosomes deliver advanced growth signals at a cellular level and are particularly effective for compromised or inflamed skin where stronger collagen stimulation is needed. As a result, PRP is often the recommended starting point, with Microneedling or Exosomes added as the treatment plan develops based on your skin’s response.
You can contact us by WhatsApp, phone or email. Alternatively, you can book your treatment online. Dr Joney De Souza Clinic is located in Marylebone, central London, within easy reach of Bond Street, Baker Street and Marble Arch tube stations.
After your HydraFacial, keep the skin clean and avoid touching the treated area. SPF should be applied the following morning and throughout your course of treatment, as the skin is more responsive to UV during the days after treatment. Avoid heavy make-up for 24 hours, intense exercise for 48 hours and heat-based activities such as saunas or steam rooms for 72 hours. Use gentle, hydrating skincare and avoid retinoids or acids for one week.
Our patients return to us year after year for natural, balanced results. Every review reflects our commitment to precision, safety and a personalised approach to aesthetic care.