CO2 Laser Resurfacing in Marylebone, London

CO2 Fractional Laser: proven resurfacing, lasting results

CO2 laser resurfacing at Dr Joney De Souza Clinic targets skin at a depth that surface treatments cannot reach. The laser removes damaged skin cells in controlled micro-columns, triggering a healing response that rebuilds collagen and renews the surface. Treatment is personalised by area, depth and energy, so results are matched to what your skin actually needs.

Price from £250. Full-face treatment from £1,800 with Dr Joney De Souza.

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Procedure time
45 to 90 minutes
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Return to work
7 to 10 days
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Recovery
7 to 10 days
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Anaesthetic
Topical cream / Oral sedation
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Sensitivity period
Redness and swelling for 1-2 weeks
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Duration of results
Several years

Who Is CO2 Laser Resurfacing For?

CO2 fractional laser resurfacing suits patients who want real skin transformation rather than subtle maintenance. At our Marylebone clinic, patients most commonly choose it for:

  • Acne scarring and post-acne skin damage
  • Deep lines and wrinkles, particularly around the eyes and mouth
  • Loose or crepey skin on the face, neck and décolletage
  • Uneven skin texture and enlarged pores
  • Sun damage and pigmentation on the face and chest
  • Periorbital lines and under-eye crepiness
  • Stretch marks on the body

Related concerns: this treatment helps with acne scarring and open pores.

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What Is CO2 Laser Resurfacing?

CO2 laser resurfacing is a medical-grade skin renewal treatment. The laser delivers controlled energy to the skin, removing the damaged outer layers in precise patterns. The more important effect, however, happens below the surface. The heat triggers the body to produce new collagen, leading to firmer, smoother, renewed skin over the following weeks and months.

Fractional vs Fully Ablative CO2

Fractional CO2 laser treats only a fraction of the skin surface at a time, leaving surrounding tissue intact to support faster healing. As a result, it offers shorter recovery than fully ablative treatments while still delivering meaningful results. Fully ablative CO2 removes the entire surface layer in the treatment area, producing more dramatic outcomes at the cost of a longer downtime. At our clinic, fractional CO2 is the standard approach, with depth and energy adjusted to match each patient.

If your main concern is pigmentation rather than texture or wrinkles, our PicoSure laser targets colour with far less downtime than CO2.

How Does CO2 Laser Resurfacing Work?

The laser emits a beam of carbon dioxide light, which is absorbed by water in skin cells. This causes the cells to vaporise in a controlled way, removing the damaged surface layer and heating the surrounding dermis. In response, the body initiates a wound-healing cascade that rebuilds collagen and elastin over the following months. Over time, the result is tighter, smoother skin with improved tone and texture.

Key Benefits of CO2 Laser Treatment in London

  • Significant reduction in acne scarring and textural irregularities
  • Deep collagen remodelling that improves skin for months after treatment
  • Visible reduction in fine lines, wrinkles and periorbital crepiness
  • Improved skin tightness and reduced skin laxity on the face and neck
  • Refined pore size and more even skin tone
  • Precision treatment by area: face, neck, décolletage or targeted zones
  • Long-lasting results from a single session in most cases

Your CO2 Laser Treatment: Step by Step

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1. Consultation and skin assessment

Your CO2 laser journey begins with a thorough consultation. Your clinician assesses your skin, reviews your medical history and discusses your goals. Together, you agree on the treatment area, the depth of resurfacing and any preparation needed before your session.

2. Pre-treatment skincare protocol

For most patients, a period of skin preparation is recommended before CO2 laser. This typically involves ZO Skin Health products over four to six weeks to prime the skin, improve healing and reduce the risk of post-inflammatory pigmentation in those with higher skin tones.

3. Topical anaesthetic

On the day of treatment, a topical anaesthetic cream is applied to the treatment area. This is left in place for thirty to sixty minutes to ensure you are comfortable throughout the procedure.

4. The laser treatment

The CO2 laser handpiece is passed across the treatment area in a controlled pattern. Your clinician adjusts the energy, density and depth of treatment to match your skin concern. Sessions typically take between forty-five and ninety minutes, depending on the area treated.

5. Immediate aftercare

Immediately after treatment, the skin is cooled and a recovery protocol begins. You can expect redness, warmth and some swelling. Your clinician reviews post-care instructions in detail before you leave the clinic.

6. Recovery and follow-up

Most patients experience a recovery period of seven to twenty-one days, during which the skin peels and renews. A follow-up appointment is scheduled at six to eight weeks to assess results and plan any further sessions if needed.

CO2 Laser Before & After Results in Marylebone

The images below show patient results following CO2 fractional laser resurfacing at Dr Joney De Souza Clinic. Individual results vary depending on the treatment area, depth of resurfacing and each patient’s skin response. A consultation with your clinician will give you a realistic picture of what to expect for your specific concern.

Before
Before
After
After

Ultraclear Laser

6 weeks post 1 treatment

Your CO2 Laser Skin Journey

First-Time Patients

For patients attending the clinic for the first time, the process begins with a thorough consultation. Your clinician reviews your skin, discusses your goals and explains whether fractional CO2 is the most appropriate option for your concern. In many cases, a period of skincare preparation is recommended before your treatment date. This is not a delay. It is the standard that produces the best results.

On the day of your session, your clinician walks you through each step so you feel fully prepared. After treatment, you leave with a clear post-care protocol and a follow-up appointment to review your progress. Most first-time patients are surprised by the improvement visible even before the skin has fully settled.

Ongoing and Repeat Treatments

CO2 fractional laser resurfacing typically produces meaningful improvement from a single session. However, patients with significant acne scarring or deeper skin laxity sometimes benefit from a second treatment, spaced at least three to six months apart to allow full collagen remodelling between sessions. Your clinician reviews your results at the follow-up and recommends the most appropriate next step.

Over time, many patients incorporate lighter maintenance treatments such as ZO Skin Health peels or polynucleotides to support and extend the collagen improvements from their CO2 session. A long-term skin plan is always discussed as part of your ongoing care at the clinic.

Before treatment

Stop using retinoids, vitamin A products and active acids (AHAs, BHAs) at least five to seven days before your treatment. Avoid sun exposure and apply SPF50 daily in the weeks leading up to your appointment. If your clinician has recommended a ZO Skin Health preparation protocol, follow it consistently. Arrive at the clinic with clean, product-free skin. Allow sixty to ninety minutes for the numbing cream to work before your session begins.

During treatment

With topical anaesthetic applied, most patients experience a warm, prickling sensation rather than pain. The handpiece is moved steadily across the treatment area. You may notice a faint odour as the laser works. This is normal. Your clinician adjusts settings throughout to ensure comfort. Sessions last between forty-five and ninety minutes depending on the area treated.

After treatment

Immediately after, the skin appears red and feels warm, similar to sunburn. Swelling peaks in the first twenty-four to forty-eight hours and then begins to subside. The skin will peel and shed over the following seven to fourteen days. This is part of the renewal process and should not be interfered with. Keep the skin clean and moisturised, avoid sun exposure entirely and do not apply makeup until the skin has fully re-epithelialised. Return to actives such as retinoids and acids only when your clinician advises, typically after four to six weeks.

Why Choose Dr Joney De Souza Clinic for CO2 Laser?

CO2 laser resurfacing produces significant results, and equally significant risks if performed incorrectly. At Dr Joney De Souza Clinic, every CO2 laser treatment is performed by a medically qualified clinician. This distinction matters when treatment depth, energy settings and patient selection directly affect both outcomes and safety.

What sets our clinic apart

  • Doctor-led treatment: Dr Joney De Souza is a practising medical doctor with extensive laser experience
  • Bespoke settings for each patient, with depth and energy never standardised
  • ZO Skin Health pre- and post-treatment protocols included in your care plan
  • Central London Marylebone location, easy to reach from across the city
  • 4.9☆ rating from over 272 verified Google reviews
  • Full aftercare support and a follow-up appointment included as standard

The laser we use, and why it matters. Our CO2 treatment uses the Deka SmartXide DOT fractional CO2 laser. This is fractional resurfacing, not fully ablative CO2. We are often asked for fully ablative CO2, which we do not offer, because the fractional approach gives meaningful results with a safer, more manageable recovery.

Always doctor-led. Every CO2 laser treatment here is carried out by a doctor. As a medical-grade laser treatment, we would not have it any other way.

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CO2 Laser Resurfacing Pricing

Pricing for CO2 fractional laser resurfacing reflects the treatment area, the depth of resurfacing and the level of clinical time involved. All prices below are for treatment with Dr Joney De Souza. Associate appointments are available at a lower rate. Contact the clinic for details.

Which CO2 Laser Treatment Is Right for You?

The right option depends on your primary concern, your tolerance for downtime and the area you want to treat. Patients focused on overall skin quality and lines across the full face most commonly choose the face or face and neck combination. Those targeting acne scarring, smoker’s lines or periorbital crepiness benefit from more focused area treatment. Scar patients are assessed individually, as the area and density of scarring determine the most appropriate approach. Your clinician will recommend the right option at consultation.

CO2 laser resurfacing pricing

Prices shown are for Dr Joney De Souza. Scar pricing is by area, confirmed at consultation.

Treatment Price

CO2 Fractional Laser, Face

£1,800

CO2 Fractional Laser, Face & Neck

£2,200

CO2 Fractional Laser, Face, Neck & Décolletage

£2,600

CO2 Fractional Laser, Madonna Eyelift

£1,000

CO2 Fractional Laser, Smoker's Lines (Mouth & Upper Lip)

£800

CO2 Fractional Laser, Individual Areas

from £900

CO2 Fractional Laser, Scars

from £250

Prices include clinical assessment. Final pricing confirmed at consultation.
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Enhance Your Results with Polynucleotides

Polynucleotides are a natural complement to CO2 laser resurfacing. Where CO2 laser works by removing and renewing the skin surface, polynucleotides work from within. They stimulate fibroblast activity, accelerate tissue repair and boost the depth of collagen remodelling. Together, they create a more comprehensive result than either treatment achieves alone.

Why combine polynucleotides with CO2 laser?

Following CO2 resurfacing, the skin enters an active healing and remodelling phase. Introducing polynucleotides two to four weeks after treatment, once the surface has fully healed, supports and extends this process. Patients who combine the two treatments often report faster recovery, greater improvement in skin hydration and density, and longer-lasting results than those who undergo CO2 laser alone. Your clinician can discuss whether this combination is appropriate for your skin at your consultation.

Learn about Polynucleotides
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Frequently Asked Questions

CO2 laser resurfacing naturally raises questions around downtime, cost, suitability and what to realistically expect. The answers below address the questions we hear most often at our Marylebone clinic.

How much does CO2 laser resurfacing cost in London?

At Dr Joney De Souza Clinic, CO2 fractional laser resurfacing starts from £250 for scar treatment. Full-face resurfacing with Dr Joney De Souza is £1,800. Face and neck combined is £2,200, and face, neck and décolletage together is £2,600. Individual areas such as the Madonna eyelift and smoker’s lines are priced separately. See the pricing table above. Associate appointments are available at a lower rate.

How many sessions of CO2 laser do I need?

Most patients achieve significant improvement from a single session. However, patients with moderate to severe acne scarring, deeper skin laxity or very uneven texture may benefit from a second treatment, spaced at least three to six months apart to allow full collagen remodelling between sessions. Your clinician reviews your results at your follow-up appointment and recommends the most appropriate next step based on your individual skin response.

Is CO2 laser worth the money?

For patients with the right concerns, CO2 fractional laser resurfacing delivers results that are difficult or impossible to achieve with lighter treatments. The improvement in acne scarring, skin tightness and surface texture is often dramatic and long-lasting. For patients prepared for the downtime and post-care commitment, the investment typically compares very favourably with repeated courses of lighter treatments that produce incremental rather than transformative results.

What is the downtime for CO2 laser?

Most patients experience a recovery period of seven to fourteen days for fractional CO2 treatment. During this time, the skin appears red and progressively peels and renews. Social downtime, when you would prefer not to be seen, is typically five to ten days. Return to work in an office setting is usually possible after seven to ten days with appropriate skincare. Heavy exercise and sun exposure should be avoided for at least two weeks after treatment.

Can CO2 laser remove acne scars?

Yes. CO2 fractional laser resurfacing is one of the most effective treatments for acne scarring. The laser removes the damaged scar surface and simultaneously stimulates deep collagen production in the dermis. Over the following weeks and months, the skin remodels and scar depth, texture and discolouration all improve. Results are cumulative, with improvement continuing for up to twelve months after a single session.

Does CO2 laser tighten skin?

Yes. The heat delivered by CO2 laser causes immediate collagen contraction, producing visible tightening within the first few weeks. Over the following three to twelve months, new collagen forms in the dermis, leading to progressive firming of the skin. This makes CO2 laser particularly effective for patients with early skin laxity on the face, neck or around the eyes.

Can CO2 laser treat stretch marks?

Yes, though results vary depending on the age, colour and depth of the stretch marks. CO2 fractional laser improves the texture and appearance of stretch marks by resurfacing the damaged skin and stimulating collagen in the underlying dermis. Newer, red or purple stretch marks typically respond better than older, white ones. Your clinician will assess the area at consultation and give you a realistic expectation of improvement.

Is CO2 laser safe for all skin tones?

Fractional CO2 laser can be used on a range of skin tones. The risk of post-inflammatory hyperpigmentation is higher in patients with Fitzpatrick skin types IV to VI. At our clinic, higher skin tones receive a thorough pre-treatment assessment, and a preparation protocol is typically recommended to reduce this risk. Your clinician will be direct about suitability and what to expect based on your individual skin tone.

What is the difference between fractional and fully ablative CO2 laser?

Fractional CO2 laser treats only a percentage of the skin surface at a time, leaving surrounding tissue intact to support faster healing. Recovery is typically seven to fourteen days. Fully ablative CO2 removes the entire surface layer in the treatment area, producing more dramatic outcomes but requiring a longer recovery of two to four weeks. At our clinic, fractional CO2 is the standard approach, with depth and energy personalised to your skin concern and downtime tolerance.

Can CO2 laser be used around the eyes?

Yes. The periorbital area is one of the most commonly treated zones with CO2 fractional laser. The Madonna Eyelift specifically targets fine lines, crepiness and mild skin laxity around the eyes. Treatment in this area requires careful technique and is always performed with protective eye shields in place. Results in the periorbital zone are typically very visible and long-lasting.

How long do CO2 laser results last?

The surface improvements in texture, tone and clarity are durable. The collagen stimulated by treatment improves skin quality for twelve to eighteen months after a single session, and in many patients the benefits are visible for several years. Natural ageing and ongoing sun exposure continue over time. For this reason, most patients combine their CO2 results with a consistent skincare routine and, where appropriate, lighter maintenance treatments in the years that follow.

Do you offer fully ablative CO2 laser?

No. We use the Deka SmartXide DOT for fractional CO2 resurfacing, which delivers meaningful results with a safer, more manageable recovery than fully ablative CO2.

What CO2 laser do you use?

We use the Deka SmartXide DOT, a medical-grade fractional CO2 laser system.

Who carries out the CO2 laser treatment?

A doctor. We treat CO2 laser as a medical procedure, from consultation through to aftercare.

CO2 Laser vs Other Treatments

Patients considering CO2 fractional laser resurfacing often want to understand how it compares to the other options available at our clinic. The questions below address the most common comparisons, safety considerations and practical booking questions.

Related reading: is CO2 laser safe and our CO2 laser recovery guide.

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4.9 ★★★★★

Read our reviews

Our patients return to us year after year for results that are natural, lasting and worth the investment. Every review below reflects a real patient experience at our Marylebone clinic.

I had CO2 laser resurfacing with Dr Joney and the results have been genuinely life-changing. My acne scarring had bothered me for years and nothing else had made a real difference. The team were incredibly professional from consultation through to recovery. I felt fully supported at every step. Six months on, my skin looks completely different. I cannot recommend this clinic highly enough.
Sarah Mitchell
Sarah Mitchell
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I genuinely wouldn’t trust anyone else with my skin. Dr Joney de Souza is meticulous, knowledgeable and takes real time to understand what you want to achieve. I had CO2 laser for fine lines and skin texture and the improvement was remarkable. The aftercare guidance was thorough and the team checked in throughout my recovery. Exceptional clinic.
Julia Edge
Julia Edge
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I couldn’t be happier with my experience at Dr Joney’s clinic. Dr Joney was incredibly professional, taking the time to understand my concerns and explain the treatment fully before we proceeded. The results speak for themselves. My skin is visibly tighter and smoother. I have been coming for over two years now and would not go anywhere else.
Filipa Franco
Filipa Franco
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Great experience overall. Dr Joney is very knowledgeable and made me feel completely at ease. The clinic is clean and professional and the results from my laser treatment were better than I expected. Recovery was exactly as described. I have been coming here for several years and always leave happy.

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Kind words that made our day 🤍

We were so touched to receive this lovely feedback from a recent client following her PicoSure face treatment with Roma - this one’s for David, Roma, and Dr Joney.

“From the moment I arrived, David and Roma made me feel so welcome and completely at ease. Roma was caring, professional, and took the time to explain the treatment thoroughly, making sure I felt comfortable and reassured throughout. Even after just one session, my skin already feels smoother and looks much more refreshed.”

Moments like this are exactly why we do what we do. It’s not just about the results (although we’re so pleased with how her skin is already responding!), it’s about making every client feel genuinely cared for from the second they walk through the door.

Thank you to our amazing client for such kind words, and to David, Roma, and Dr Joney for the warmth and care you bring to every single appointment 🫶HydraFacial: the secret to that red-carpet glow ✨

Ever wondered what actually happens during a HydraFacial? Here’s a look inside the treatment, step by step, at Dr Joney De Souza.

It begins with a deep cleanse and exfoliation to clear away impurities and prepare the skin, followed by gentle extractions that refine congestion with complete comfort and precision. 

From there, targeted serums and boosters are infused into the skin, tailored entirely to your individual needs, before LED light therapy supports the skin’s long-term health and renewal. 

The treatment finishes with an antioxidant infusion, sealing in radiance for that lit-from-within finish.

This particular treatment was our Deluxe HydraFacial, though for those wanting to elevate the experience further, our Platinum HydraFacial also includes lymphatic drainage, perfect for extra de-puffing and detoxification alongside all the usual glow-boosting benefits.

The result is skin that looks cleansed, replenished, and effortlessly glowing, delivered with the precision and care that defines every treatment here.

📍 Marylebone, London | 020 7043 0748 📱Sculptra vs Juläine: which biostimulator is right for you? 💭

Both Sculptra and Juläine are poly-L-lactic acid (PLLA) biostimulators - meaning rather than simply adding volume, they work by encouraging your skin to produce its own natural collagen over time, for results that look and feel truly you.

Sculptra is the original PLLA injectable, with a long-established track record for stimulating collagen and improving skin structure and firmness gradually over several months, with results that can last up to two years.

Juläine is a newer generation PLLA treatment, using more uniform, highly purified microspheres engineered to mix more evenly, which can help reduce inflammation caused by treatment. Like Sculptra, results build gradually, with visible improvements from a few weeks in and full effects developing over a few months. 

Both are excellent options for restoring facial volume, improving skin quality, and softening lines. The right choice really depends on your skin, goals, and what your practitioner recommends for you.

Not sure which is best suited to your skin and goals? Get in touch with us today to book your consultation.

📍Marylebone, London | 020 7043 0748 📱Product Spotlight | Daily Power Defense ✨

ZO Skin Health’s Daily Power Defense is one of those products that quietly does a lot of the heavy lifting in a skincare routine, and it’s become a firm favourite of ours here at the clinic.

Formulated with Vitamins A and E, it helps protect the skin against environmental damage and free radicals, while supporting barrier restoration and long-lasting hydration.
Over time, this can mean fewer visible signs of premature ageing and a stronger, more resilient complexion.

It’s a lightweight daily step, but one that adds up - the kind of product that supports your skin quietly in the background, day after day.

If you’re curious whether it fits into your routine, drop us a DM, or ask at your next appointment 📅

How can you find us?

Our clinic is located in Marylebone, London, in the heart of one of Central London’s most prestigious and renowned medical districts. Perfectly positioned for convenience and discretion, we are easily accessible from across the capital and beyond.

We welcome patients from Mayfair, Harley Street, Marylebone, Knightsbridge, Belgravia, Chelsea, Kensington, Fitzrovia and St John’s Wood, as well as international patients visiting London for specialist treatment.

Our location benefits from excellent transport connections, with close proximity to major Underground stations, mainline rail links and direct access to Heathrow, Gatwick and London City airports. Several secure parking facilities and convenient chauffeur drop-off points are available nearby, ensuring a seamless and comfortable visit.

Whether you are travelling from elsewhere in London, across the UK or internationally, our clinic offers a calm, private and exclusive setting in one of the world’s leading medical destinations.

Opening hours
Monday
9 am to 6 pm
Tuesday
9 am to 6 pm
Wednesday
9 am to 6 pm
Thursday
9 am to 6 pm
Friday
9 am to 6 pm
Saturday
Closed
Sunday
Closed
Dr Joney De Souza
49 Blandford St, London W1U 7HH
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