woman-with-wrinkles

PRF (Platelet-Rich Fibrin) Treatment in London

PRF (platelet-rich fibrin) is an advanced regenerative treatment that uses your own blood to stimulate collagen, improve skin quality and support hair growth with Dr Joney De Souza in Marylebone, London.

Your Own Blood Promotes Healthy Skin Activity

PRP For Hair Loss Treatment  Summary

number-graphic
No. of treatments
Initially a course of 2 treatments spaced six to eight weeks apart
time-graphic
Procedure time
60 minutes
laptop-graphic
Back to work
After 2 days
recovery-graphic
Duration of results
Maximum results after 6 months but skin continues to improve over time.
heart-graphic
Anaesthetic
A topical anaesthetic may be applied as needed
hazard-inspect-graphic
Sensitivity period
3 days
Price From
£550*
*Prices vary based on number of treatment areas. View our full pricing information below.

PRF Platelet-Rich Fibrins with Dr Joney De Souza in Marylebone, London

PRF, or platelet-rich fibrin, is a newer generation of PRP (platelet-rich plasma) preparation that can be used in a variety of treatments to regenerate collagen and reverse the signs of ageing. PRF at the clinic in London can also be combined with LED light to achieve an even more effective result. This treatment is also excellent for stimulating hair growth and is often considered for hair loss.

Is PRF the Same as PRP for Hair Loss?

No. While PRF and PRP are closely related, they are not the same treatment.

Both PRF and PRP involve taking a small sample of your blood, processing it, and injecting the resulting solution into the scalp. The key differences lie in how the blood is processed and what the final injectable solution contains.

PRF is prepared using a slower centrifugation process and without the use of anticoagulants. This allows a natural fibrin matrix to form, which supports a slower, more sustained release of growth factors over time.

PRP, on the other hand, is processed at higher speeds and requires an anticoagulant. The result is a platelet-rich plasma solution that releases growth factors more quickly, but over a shorter duration.

Find us in Marylebone
dr-joney-clinic-exterior-open-door
joney-platelet-rich-plasma

What can PRF do for me?

This treatment can improve skin texture. Expect skin to become more luminous, hydrated and nourished, firmer and with improved texture. PRF is a natural aesthetic treatment that can rejuvenate your face or under-eye area, or effectively treat hair loss by stimulating regrowth. A series of treatments is often advised to achieve the best results.

What results can I expect from PRF for hair loss?

PRF does not create new hair follicles, but it can help strengthen existing follicles, slow further hair loss, and encourage healthier, thicker hair growth. Improvements are typically gradual and may include reduced shedding, increased hair density, and improved scalp quality.

For best results, PRF is often performed as a course of treatments, with maintenance sessions recommended depending on the individual and the underlying cause of hair loss.

Meet Dr Joney
clinic-illuminated-promo
Dr-Joney-treating-hands

(PRF) platelet-rich fibrin frequently asked questions

PRF uses your own blood, which is processed in a centrifuge to separate platelets and other plasma components including a fibrin matrix and white blood cells. Platelets and fibrin are rich in growth factors that help boost the skin’s collagen production. Because PRF releases slower than some alternatives, it can have a longer-lasting anti-ageing effect

What our clients say

“I had this treatment done because I wanted something completely natural, and since it used my own blood I knew that it would be.  I was amazed at the results, especially on my décolletage which was very sun-damaged.”

Who is PRF suitable for?

Platelet-rich fibrin (PRF) is suitable for patients looking for a natural, regenerative approach to skin rejuvenation or hair restoration, using their own blood-derived growth factors.

PRF may be particularly suitable if you are looking to:

  • Improve early signs of skin ageing, such as fine lines, crepiness or loss of elasticity

  • Treat under-eye hollowness, dark circles or tired-looking eyes

  • Support hair regrowth or slow hair thinning

  • Improve overall skin quality and collagen stimulation

  • Avoid synthetic fillers or additives

  • Choose a treatment with minimal downtime and a strong safety profile

Because PRF uses your own blood and contains no anticoagulants or synthetic substances, it is often well tolerated and appealing to patients seeking a more biologically driven treatment.

A consultation with our expert team is always required to confirm suitability and tailor treatment to your concerns.

Ask us your question
What Is PRF?

PRF stands for Platelet-Rich Fibrin. It is an advanced regenerative treatment created from a small sample of your own blood.

The blood is processed using low-speed centrifugation, without anticoagulants. This preserves a natural fibrin matrix alongside platelets and white blood cells, allowing growth factors to be released slowly over time.

PRF is used in aesthetic medicine to improve skin quality, stimulate collagen production, and support tissue regeneration.

What Is PRF Treatment?

PRF treatment involves injecting platelet-rich fibrin into targeted areas of the skin or scalp.

In aesthetic treatments, PRF is commonly used for:

  • Under-eye rejuvenation

  • Facial skin regeneration

  • Hair loss and scalp stimulation

The aim is not to add volume in the way dermal fillers do, but to improve the quality, strength and regenerative capacity of the tissue itself.

What’s the treatment like?

A small amount of your blood is drawn and placed in a centrifuge. This separates red blood cells from plasma rich in platelets, fibrin and growth factors. The resulting platelet-rich fibrin is re-injected into the treatment area. It may be administered via multiple micro-injections (like mesotherapy), directly into lines or wrinkles (similar to a filler), or deeper into the dermis (like a volumiser). The process is comparable in comfort to other injectables; a topical anaesthetic cream may be applied beforehand. Some practitioners combine PRF with other “self-heal” treatments (e.g. microneedling) to enhance results.

What Does PRF Do?

PRF works by delivering a sustained release of growth factors that:

  • Stimulate collagen and elastin production

  • Improve blood supply to treated areas

  • Support tissue repair and regeneration

  • Strengthen hair follicles and scalp health

This gradual biological response is what differentiates PRF from faster-acting injectable treatments.

How is PRF different from PRP treatments?

PRF is a more advanced form of platelet therapy that contains a higher concentration of growth factors and a fibrin matrix, allowing them to be released more slowly over time. This can lead to longer-lasting skin quality improvements compared to PRP.

What areas can be treated with PRF?

PRF is commonly used for delicate areas such as under the eyes, face, neck and décolletage, where skin quality, hydration and fine lines are concerns. It can also be used more broadly to support collagen stimulation and improve overall skin texture and tone.

When will I start to see results from PRF treatment?

Initial improvements in skin quality may be noticed within a few weeks, with continued enhancement over the following months as collagen production is stimulated. Because PRF works gradually, results develop naturally rather than appearing immediately after treatment.

How many PRF sessions will I need?

Most patients benefit from a course of treatments, typically spaced several weeks apart, depending on skin condition and treatment goals. Dr Joney will recommend a personalised plan during consultation to ensure results are achieved safely and effectively.

Is PRF safe and suitable for sensitive skin?

PRF is derived entirely from your own blood, meaning there are no synthetic additives or foreign substances involved. This makes it particularly suitable for patients with sensitive skin or those seeking a natural approach to skin rejuvenation, following appropriate medical assessment.

What Is PRF Under Eyes?

PRF under the eyes is used to improve:

  • Dark circles

  • Fine lines

  • Crepey skin

  • Mild hollowing

Because PRF improves skin quality rather than adding volume, it is particularly suited to the delicate under-eye area where traditional fillers may not be appropriate.

How Much Does PRF Cost?

The cost of PRF varies depending on:

  • Treatment area

  • Number of sessions required

  • Whether PRF is combined with other treatments

Exact pricing is confirmed following a consultation, where a personalised treatment plan is created. Our From Pricing is £550* with more pricing available on our pricing page.

Book your consultation for PRF in London with Dr Joney De Souza Clinic in Marylebone

Every PRF Hair Loss treatment at Dr Joney De Souza Clinic begins with a comprehensive consultation. During this appointment, Dr Joney and our expert team will take time to understand your goals, assess your skin condition and discuss the areas you would like to improve. He will explain how PRF works, what results you can expect, and whether combining it with treatments such as microneedling or LED may further enhance your outcome.

Once your personalised plan is agreed, a small sample of your blood is gently collected and placed into a centrifuge to isolate the platelet-rich plasma. The skin is then cleansed, and a topical anaesthetic may be applied to ensure comfort. Using precise injection or microneedling techniques, your physician introduces the concentrated growth factors back into the skin to stimulate repair, boost collagen and promote healthier, more radiant tissue. The procedure is safe, natural and minimally invasive, with little discomfort.

PRP for Hair Loss PRF for Hair Loss
Extracted from a small sample of your own blood Extracted from a small sample of your own blood
Processed using high-speed centrifugation Processed using low-speed centrifugation
Anticoagulant added during processing No anticoagulant used
Contains platelet-rich plasma only Contains platelets, white blood cells and fibrin
Rapid release of growth factors Slow, sustained release of growth factors
Shorter biological activity window Longer-lasting regenerative activity
Book a consultation
joney-platelet-rich-plasma
Dr-Joney-patient-injection
 4.9 ★★★★★

Read our reviews including PRF treatments in London

Our patients return to us year after year for natural, balanced results. Every review reflects our commitment to precision, safety and a personalised approach to aesthetic care.

I genuinely wouldn’t trust anyone else with my skin. Dr Joney de Souza remains my top recommendation for anyone seeking expert aesthetic care in London. He has a calm, professional manner and always takes the time to truly listen and understand what you’re hoping to achieve. His approach is natural and refined, you always leave looking like the best version of yourself, never overdone. The clinic is a beautiful, welcoming space in the heart of London, and the entire team is warm, knowledgeable, and highly professional. Dr Joney’s expertise and eye for detail are truly exceptional, and the results speak for themselves.
Daniele Bernardinetti
Daniele Bernardinetti
View on Google
I’ve known Dr. Joney de Souza for years and can’t recommend him highly enough. He’s a true expert in aesthetics — always professional, innovative, and genuinely caring. His treatments are subtle, natural, and always tailored to your needs. A standout in London’s aesthetic scene!
Osmar Pinheiro Bacelar Junior
Osmar Pinheiro Bacelar Junior
View on Google
I had treatment at Dr. Joney De Souza’s clinic one month ago and had a fantastic experience. Dr. De Souza was friendly, highly knowledgeable, and made me feel completely comfortable and at ease throughout the process. His great sense of humor also helped create a relaxed atmosphere. I’m really happy with the results and will definitely be coming back for regular visits. Highly recommend this clinic!
Daluna London
Daluna London
View on Google
The clinic is so very welcoming and really listens to how and what you would like to achieve, i have had several facial treatments and it has made such a difference to my confidence. David and everyone in the clinic are professional and experts in what they do, they treat you with a really personal service. My skin has never looked so clear or glowing .. I’ve had people stop and ask me what and where do I have my treatments .. thank you
Jayne Gates
Jayne Gates
View on Google
I had an excellent experience with Dr. Joney de Souza and his team. From start to finish, they were incredibly supportive, making me feel at ease throughout the entire process. Dr. Joney has both a sharp eye and a soft hand, striking the perfect balance between precision and gentleness. The team’s expertise speaks for itself, and their approach is as refined as it is reassuring. Highly recommended.

Follow us on Instagram

Did you know we stock the incredible @zoskinhealth at our clinic? 💙

At our clinic, we only align with brands that deliver real, visible results - which is why we proudly stock and use ZO Skin Health.

Developed by world-renowned dermatologists, ZO is a leading medical-grade skincare brand designed to transform skin at a cellular level; not just treat it on the surface.

Why we trust ZO:

💙 Clinically proven, science-backed formulations

🤍 Targets a wide range of concerns: acne, pigmentation, ageing + texture

💙 Strengthens and restores overall skin health

🤍 High-potency active ingredients for real, lasting results

💙 Medical-grade protocols tailored to each individual

This isn’t just skincare - it’s skin transformation.

Because your skin deserves more than basic. It deserves expert-led, results-driven care.

#zoskinhealth #zoskin #drjoney #londonskin #medicalgradeskincare

How can you find us?

Our clinic is located in Marylebone, London, in the heart of one of Central London’s most prestigious and renowned medical districts. Perfectly positioned for convenience and discretion, we are easily accessible from across the capital and beyond.

We welcome patients from Mayfair, Harley Street, Marylebone, Knightsbridge, Belgravia, Chelsea, Kensington, Fitzrovia and St John’s Wood, as well as international patients visiting London for specialist treatment.

Our location benefits from excellent transport connections, with close proximity to major Underground stations, mainline rail links and direct access to Heathrow, Gatwick and London City airports. Several secure parking facilities and convenient chauffeur drop-off points are available nearby, ensuring a seamless and comfortable visit.

Whether you are travelling from elsewhere in London, across the UK or internationally, our clinic offers a calm, private and exclusive setting in one of the world’s leading medical destinations.

Opening hours
Monday
9 am–6 pm
Tuesday
9 am–6 pm
Wednesday
9 am–6 pm
Thursday
9 am–6 pm
Friday
9 am–6 pm
Saturday
Closed
Sunday
Closed
Dr Joney De Souza
49 Blandford St, London W1U 7HH
Get directions
Whatsapp