
PRF (platelet-rich fibrin) is an advanced regenerative treatment that uses your own blood to stimulate collagen, improve skin quality and support hair growth with Dr Joney De Souza in Marylebone, London.
PRP For Hair Loss Treatment Summary
This treatment can improve skin texture. Expect skin to become more luminous, hydrated and nourished, firmer and with improved texture. PRF is a natural aesthetic treatment that can rejuvenate your face or under-eye area, or effectively treat hair loss by stimulating regrowth. A series of treatments is often advised to achieve the best results.
PRF does not create new hair follicles, but it can help strengthen existing follicles, slow further hair loss, and encourage healthier, thicker hair growth. Improvements are typically gradual and may include reduced shedding, increased hair density, and improved scalp quality.
For best results, PRF is often performed as a course of treatments, with maintenance sessions recommended depending on the individual and the underlying cause of hair loss.


PRF uses your own blood, which is processed in a centrifuge to separate platelets and other plasma components including a fibrin matrix and white blood cells. Platelets and fibrin are rich in growth factors that help boost the skin’s collagen production. Because PRF releases slower than some alternatives, it can have a longer-lasting anti-ageing effect
“I had this treatment done because I wanted something completely natural, and since it used my own blood I knew that it would be. I was amazed at the results, especially on my décolletage which was very sun-damaged.”
Platelet-rich fibrin (PRF) is suitable for patients looking for a natural, regenerative approach to skin rejuvenation or hair restoration, using their own blood-derived growth factors.
PRF may be particularly suitable if you are looking to:
Improve early signs of skin ageing, such as fine lines, crepiness or loss of elasticity
Treat under-eye hollowness, dark circles or tired-looking eyes
Support hair regrowth or slow hair thinning
Improve overall skin quality and collagen stimulation
Avoid synthetic fillers or additives
Choose a treatment with minimal downtime and a strong safety profile
Because PRF uses your own blood and contains no anticoagulants or synthetic substances, it is often well tolerated and appealing to patients seeking a more biologically driven treatment.
A consultation with our expert team is always required to confirm suitability and tailor treatment to your concerns.
PRF stands for Platelet-Rich Fibrin. It is an advanced regenerative treatment created from a small sample of your own blood.
The blood is processed using low-speed centrifugation, without anticoagulants. This preserves a natural fibrin matrix alongside platelets and white blood cells, allowing growth factors to be released slowly over time.
PRF is used in aesthetic medicine to improve skin quality, stimulate collagen production, and support tissue regeneration.
PRF treatment involves injecting platelet-rich fibrin into targeted areas of the skin or scalp.
In aesthetic treatments, PRF is commonly used for:
Under-eye rejuvenation
Facial skin regeneration
Hair loss and scalp stimulation
The aim is not to add volume in the way dermal fillers do, but to improve the quality, strength and regenerative capacity of the tissue itself.
A small amount of your blood is drawn and placed in a centrifuge. This separates red blood cells from plasma rich in platelets, fibrin and growth factors. The resulting platelet-rich fibrin is re-injected into the treatment area. It may be administered via multiple micro-injections (like mesotherapy), directly into lines or wrinkles (similar to a filler), or deeper into the dermis (like a volumiser). The process is comparable in comfort to other injectables; a topical anaesthetic cream may be applied beforehand. Some practitioners combine PRF with other “self-heal” treatments (e.g. microneedling) to enhance results.
PRF works by delivering a sustained release of growth factors that:
Stimulate collagen and elastin production
Improve blood supply to treated areas
Support tissue repair and regeneration
Strengthen hair follicles and scalp health
This gradual biological response is what differentiates PRF from faster-acting injectable treatments.
PRF is a more advanced form of platelet therapy that contains a higher concentration of growth factors and a fibrin matrix, allowing them to be released more slowly over time. This can lead to longer-lasting skin quality improvements compared to PRP.
PRF is commonly used for delicate areas such as under the eyes, face, neck and décolletage, where skin quality, hydration and fine lines are concerns. It can also be used more broadly to support collagen stimulation and improve overall skin texture and tone.
Initial improvements in skin quality may be noticed within a few weeks, with continued enhancement over the following months as collagen production is stimulated. Because PRF works gradually, results develop naturally rather than appearing immediately after treatment.
Most patients benefit from a course of treatments, typically spaced several weeks apart, depending on skin condition and treatment goals. Dr Joney will recommend a personalised plan during consultation to ensure results are achieved safely and effectively.
PRF is derived entirely from your own blood, meaning there are no synthetic additives or foreign substances involved. This makes it particularly suitable for patients with sensitive skin or those seeking a natural approach to skin rejuvenation, following appropriate medical assessment.
PRF under the eyes is used to improve:
Dark circles
Fine lines
Crepey skin
Mild hollowing
Because PRF improves skin quality rather than adding volume, it is particularly suited to the delicate under-eye area where traditional fillers may not be appropriate.
The cost of PRF varies depending on:
Treatment area
Number of sessions required
Whether PRF is combined with other treatments
Exact pricing is confirmed following a consultation, where a personalised treatment plan is created. Our From Pricing is £550* with more pricing available on our pricing page.
Every PRF Hair Loss treatment at Dr Joney De Souza Clinic begins with a comprehensive consultation. During this appointment, Dr Joney and our expert team will take time to understand your goals, assess your skin condition and discuss the areas you would like to improve. He will explain how PRF works, what results you can expect, and whether combining it with treatments such as microneedling or LED may further enhance your outcome.
Once your personalised plan is agreed, a small sample of your blood is gently collected and placed into a centrifuge to isolate the platelet-rich plasma. The skin is then cleansed, and a topical anaesthetic may be applied to ensure comfort. Using precise injection or microneedling techniques, your physician introduces the concentrated growth factors back into the skin to stimulate repair, boost collagen and promote healthier, more radiant tissue. The procedure is safe, natural and minimally invasive, with little discomfort.
| PRP for Hair Loss | PRF for Hair Loss |
|---|---|
| Extracted from a small sample of your own blood | Extracted from a small sample of your own blood |
| Processed using high-speed centrifugation | Processed using low-speed centrifugation |
| Anticoagulant added during processing | No anticoagulant used |
| Contains platelet-rich plasma only | Contains platelets, white blood cells and fibrin |
| Rapid release of growth factors | Slow, sustained release of growth factors |
| Shorter biological activity window | Longer-lasting regenerative activity |


Our patients return to us year after year for natural, balanced results. Every review reflects our commitment to precision, safety and a personalised approach to aesthetic care.

Our team would love to hear from you. Whether you have questions, need guidance, or simply want to explore your treatment options, we’re here to support you every step of the way. If you would like to place an online booking you can do this via our online booking system.
Dr Joney De Souza Skin and Laser Clinic is located in central Marylebone and is easily accessible by public transport or car, with Bond Street, Oxford Circus and Baker Street Underground stations all just a short walk away. For those driving, paid on-street parking and nearby public car parks are available, making the clinic convenient to reach from across London, including Mayfair and Soho.