Profhilo Treatment

Profhilo treatment in Marylebone at Dr Joney De Souza Clinic boosts hydration, improves elasticity and restores youthful firmness. This powerful skin booster remodels and rejuvenates the skin for natural, long lasting radiance. Book your consultation today.

Skin rejuvenation with Profhilo

Profhilo Treatment Summary

No. of treatments
one treatment will give results which should last up-to 6 months
Procedure time
45 minutes
Back to work
Immediate
Duration of results
Results may last up to 6 months months
Anaesthetic
Given as needed
Sensitivity period
Minimal
Price From
£450
*Prices vary based on number of treatment areas. View our full pricing information below.

Profhilo Treatments in Marylebone, London

Profhilo is an award-winning skin bio-remodelling treatment now available at Dr Joney De Souza Skin and Laser Clinic. This unique injectable treatment uses high concentrations of natural Hyaluronic Acid (HA), enabling its powerful hydrating properties to stimulate tissue, encouraging long-lasting neocollagenesis. Profhilo can help to improve skin tone, texture, elasticity, firmness, hydration and radiance.

Profhilo works to rejuvenate and nourish dermal cells, providing long-lasting improvements to the health and appearance of your skin for up to 4-6 months after treatment. By boosting the skin’s own collagen production, skin is left feeling firm, hydrated and glowing!

Find us in Marylebone
 4.9 ★★★★★ 268 reviews

Read our reviews

Our patients return to us year after year for natural, balanced results. Every review reflects our commitment to precision, safety and a personalised approach to aesthetic care.

I genuinely wouldn’t trust anyone else with my skin. Dr Joney de Souza remains my top recommendation for anyone seeking expert aesthetic care in London. He has a calm, professional manner and always takes the time to truly listen and understand what you’re hoping to achieve. His approach is natural and refined, you always leave looking like the best version of yourself, never overdone. The clinic is a beautiful, welcoming space in the heart of London, and the entire team is warm, knowledgeable, and highly professional. Dr Joney’s expertise and eye for detail are truly exceptional, and the results speak for themselves.
Daniele Bernardinetti
Daniele Bernardinetti
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I’ve known Dr. Joney de Souza for years and can’t recommend him highly enough. He’s a true expert in aesthetics — always professional, innovative, and genuinely caring. His treatments are subtle, natural, and always tailored to your needs. A standout in London’s aesthetic scene!
Osmar Pinheiro Bacelar Junior
Osmar Pinheiro Bacelar Junior
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I had treatment at Dr. Joney De Souza’s clinic one month ago and had a fantastic experience. Dr. De Souza was friendly, highly knowledgeable, and made me feel completely comfortable and at ease throughout the process. His great sense of humor also helped create a relaxed atmosphere. I’m really happy with the results and will definitely be coming back for regular visits. Highly recommend this clinic!
Daluna London
Daluna London
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The clinic is so very welcoming and really listens to how and what you would like to achieve, i have had several facial treatments and it has made such a difference to my confidence. David and everyone in the clinic are professional and experts in what they do, they treat you with a really personal service. My skin has never looked so clear or glowing .. I’ve had people stop and ask me what and where do I have my treatments .. thank you
Jayne Gates
Jayne Gates
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I had an excellent experience with Dr. Joney de Souza and his team. From start to finish, they were incredibly supportive, making me feel at ease throughout the entire process. Dr. Joney has both a sharp eye and a soft hand, striking the perfect balance between precision and gentleness. The team’s expertise speaks for itself, and their approach is as refined as it is reassuring. Highly recommended.

Skin Quality Is the Foundation

Botox has become one of the most trusted and widely used treatments for softening expression lines and maintaining a fresher, more relaxed appearance. Increasingly, people are choosing to start treatment earlier as a preventative approach, addressing fine lines before they become deeply set.

Rather than altering facial shape or expression, Botox works by calming the overactive muscles that contribute to frown lines, forehead creases and crow’s feet over time. When performed with precision and a light hand, it helps preserve natural movement while slowing the formation of future wrinkles. At Dr Joney De Souza Clinic, the focus is always on subtlety, balance and long term skin health, using advanced techniques to achieve results that look effortless, not obvious.

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Profhilo Frequently Asked Questions

Profhilo is an innovative skin remodelling treatment designed to improve hydration, elasticity and overall skin quality. It contains one of the highest concentrations of pure hyaluronic acid available and works by stimulating collagen and elastin production rather than adding volume or altering facial structure.

Profhilo is a non-surgical, quick and safe procedure. Small, precise injections are placed just beneath the skin where the product spreads naturally across the tissue, delivering deep hydration and improving firmness. It is especially effective for areas that show early signs of ageing such as the cheeks, lower face, neck and décolletage.

There is minimal downtime. You may experience slight redness, swelling or small bumps at the injection points, which typically settle within a few hours. Results develop gradually over the following weeks as the skin becomes smoother, tighter and more radiant. Most patients complete an initial course of two sessions four weeks apart, with results lasting around six months depending on individual skin condition and lifestyle.

Ask us your question
What can Profhilo do for me?

Profhilo works to improve your complexion by nourishing the dermal cells, resulting in radiant and rejuvenated skin. It can also help to combat the signs of ageing before they appear thanks to its intense hydrating capabilities. However, the most evident changes are seen when treating the appearance of lines, wrinkles, sagging, thinning and crepe-like skin. Profhilo effectively lifts and tightens the skin increasing firmness and elasticity with results that continue to improve for up to 6 months.

Who is suitable?

You will be invited for a medical consultation to assess your suitability for Profhilo treatment.

Which areas can Profhilo treat?

Profhilo is most commonly used on the face, but it can also treat:

  • Neck

  • Décolletage

  • Hands

  • Upper arms

  • Areas of crepey or lax skin

It is ideal for improving texture, hydration and elasticity.

How many Profhilo sessions do I need?

Most patients require an initial course of two treatments, spaced four weeks apart.
Some may benefit from a third session depending on their skin condition. Maintenance every 6 months is recommended for ongoing results.

Does Profhilo hurt?

Discomfort is minimal. The injections are quick, and most patients describe only a brief stinging sensation. A topical anaesthetic can be applied if needed.

Is there any downtime?

Downtime is very minimal. You may notice small bumps, redness or swelling at the injection points, which usually settle within a few hours. Normal daily activities can be resumed right away.

When will I see results?

You may notice early hydration improvements within a few days. The full skin remodelling effect develops 2–6 weeks after the second treatment, as collagen and elastin production increases.

How long do Profhilo results last?

Results typically last around 6 months, depending on age, skin quality and lifestyle. Regular maintenance treatments help maintain long-term skin improvement.

Can Profhilo be combined with other treatments?

Yes. Profhilo works beautifully alongside dermal fillers, Botox, microneedling, skin boosters and energy-based treatments. Dr Joney will advise on the best combination for your skin goals.

Is Profhilo suitable for everyone?

Profhilo is suitable for a wide range of skin types and ages, particularly those experiencing early signs of ageing, dehydration or loss of firmness. A consultation is required to ensure suitability, especially if you are pregnant, breastfeeding or have certain medical conditions.

Will Profhilo make me look different?

No. Profhilo does not change facial structure or add volume. It improves skin quality from within, giving a healthier, fresher and more radiant appearance while keeping your natural features intact.

Your Profhilo Treatment Journey at Dr Joney De Souza Clinic

Every Profhilo treatment at Dr Joney De Souza Clinic begins with a thorough consultation. During this appointment, Dr Joney will take time to understand your skin goals, assess your hydration levels, elasticity and overall skin quality, and identify the areas that will benefit most from treatment. He will explain how Profhilo works, what improvements you can expect, and whether combining it with other treatments may help achieve optimal results.

Once your personalised plan is agreed, the skin is gently cleansed and a topical anaesthetic may be applied to ensure comfort. Using precise injection techniques, Dr Joney administers small amounts of Profhilo into a series of bio-aesthetic points just beneath the skin. The treatment is quick and designed to distribute the hyaluronic acid evenly across the tissue, stimulating collagen and elastin for a naturally refreshed, hydrated and lifted appearance. Discomfort is minimal and there is no significant downtime.

Aftercare

Following your Profhilo treatment, you can return to most daily activities straight away. You may notice slight redness, swelling or small visible bumps at the injection sites. These are completely normal and typically disappear within a few hours to 24 hours as the product begins to disperse through the skin.

Dr Joney will provide personalised aftercare advice, which may include avoiding strenuous exercise, heat treatments and applying pressure to the treated areas for 24 to 48 hours. As the active ingredients stimulate the skin’s natural repair processes, you will begin to notice improvements in hydration, smoothness and firmness over the following days. Results continue to develop after the second treatment session, usually performed four weeks later.

With regular maintenance every six months, your skin will remain brighter, more elastic and naturally rejuvenated, while maintaining the soft, subtle and refreshed look that Profhilo is known for.

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Profhilo Treatment Prices At Dr Joney De Souza in Marylebone, London

You can rest assured that we only use the highest quality UK sourced products at our clinic, this includes only the most premium dermal fillers and the most advanced FDA approved technologies. With the highest levels of customer service and expertise, our focus is on you – just have a look at our amazing reviews.

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Profhilo Pricing

All treatments consist of 1 session unless it is a package, which will have multiple sessions based on treatment.

All Pricing is in GBP.

Area/TreatmentPrices with Dr JoneyPrice with Associate

Profhilo - 1 area

475

400

Profhilo - 2 areas

800

680

Profhilo - 3 areas

1,000

850

Profhilo - Mouth area (‘smoker’s lines’) & Lower face

1,650

1,400

Profhilo Body - 1 area

475

400

Profhilo Body - 2 areas

780

665

All of our pricing is based on a thorough consultation. All Pricing is in GBP. * 1 treatment session * 2 treatment sessions
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About Us

Based at 49 Blandford Street in Marylebone, Dr Joney De Souza Skin & Laser Clinic is known for its refined, personalised approach to aesthetic medicine. Under the expert care of Dr Joney, every treatment is tailored to enhance natural beauty and maintain long-term skin health.

Dr Joney will advise you on aftercare, such as avoiding strenuous exercise or massaging the area for 24 hours. Many patients choose to book a review appointment around two weeks later, where any fine-tuning can be carried out if necessary.

Results typically last between three to six months, depending on your individual response and the area treated. With regular maintenance treatments, you’ll notice smoother skin, softer lines, and a fresher, more relaxed appearance that still looks entirely natural.

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Book a Consultation

Our team would love to hear from you. Whether you have questions, need guidance, or simply want to explore your treatment options, we’re here to support you every step of the way. Reach out in whichever way feels easiest

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Contact us today to book your consultation with Dr Joney De Souza.

Opening hours
Monday
9am - 6pm
Tuesday
9am - 6pm
Wednesday
9am - 6pm
Thursday
9am - 6pm
Friday
9am - 6pm
Saturday
Closed
Sunday
Closed
Dr Joney De Souza
49 Blandford St, London W1U 7HH
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