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Profhilo Treatment by Harley Street

Profhilo is commonly recommended for patients in Harley Street experiencing reduced skin elasticity, fine textural changes, or early laxity who want improvement without volumising fillers. At Dr Joney De Souza’s London clinic, treatment planning is guided by anatomical assessment and realistic outcome discussion.

Skin rejuvenation using Profhilo near Harley Street

Profhilo Treatment Summary

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No. of treatments
one treatment will give results which should last up-to 6 months
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Procedure time
45 minutes
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Back to work
Immediate
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Duration of results
Results may last up to 6 months months
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Anaesthetic
Given as needed
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Sensitivity period
Minimal
Price From
£450
*Prices vary based on number of treatment areas. View our full pricing information below.

Why Harley Street patients consider Profhilo

Patients in the Harley Street area often prioritise treatments that improve skin integrity while maintaining natural facial proportions. Profhilo aligns with this approach because it enhances hydration and collagen stimulation rather than reshaping facial contours.

Instead of altering structure, Profhilo supports skin quality at a cellular level. This makes it suitable for individuals who want subtle improvement in firmness and elasticity without augmentation.

Consultation focuses on skin condition, ageing patterns, and suitability before treatment proceeds.

Learn more on Profhilo around Harley Street

The clinical mechanism behind Profhilo

Profhilo contains a stabilised, high concentration of hyaluronic acid formulated to diffuse through the skin after injection. Once administered at specific points, it stimulates collagen and elastin production, improving skin firmness and texture over time.

Treatment is commonly performed on:

  • Face

  • Neck

  • Décolletage

  • Hands

Because Profhilo works through bioremodelling rather than filling, it is often selected for patients who want overall skin improvement rather than contour change.

Patients are encouraged to review the main Profhilo treatment information page for detailed explanation of technique and suitability.

Talk to us about Profhilo hand treatments
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Access from Harley Street

The clinic is conveniently located near Harley Street and easily accessible on foot or via nearby Underground stations such as Regent’s Park, Oxford Circus, or Bond Street.

Given the minimal downtime associated with Profhilo, Harley Street patients often schedule treatment during regular working weeks without extended recovery planning.

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Your Profhilo Journey at our Harley Street clinic

If you’re considering Profhilo in the Harley Street area, consultation is essential to determine whether the treatment aligns with your skin condition and expectations. During this appointment, Dr Joney will take time to understand your skin goals, assess your hydration levels, elasticity and overall skin quality, and identify the areas that will benefit most from treatment. He will explain how Profhilo works, what improvements you can expect, and whether combining it with other treatments may help achieve optimal results.

Once your personalised plan is agreed, the skin is gently cleansed and a topical anaesthetic may be applied to ensure comfort. Using precise injection techniques, Dr Joney administers small amounts of Profhilo into a series of bio-aesthetic points just beneath the skin. The treatment is quick and designed to distribute the hyaluronic acid evenly across the tissue, stimulating collagen and elastin for a naturally refreshed, hydrated and lifted appearance. Discomfort is minimal and there is no significant downtime.

Aftercare

Following your Profhilo treatment, you can return to most daily activities straight away. You may notice slight redness, swelling or small visible bumps at the injection sites. These are completely normal and typically disappear within a few hours to 24 hours as the product begins to disperse through the skin.

Dr Joney will provide personalised aftercare advice, which may include avoiding strenuous exercise, heat treatments and applying pressure to the treated areas for 24 to 48 hours. As the active ingredients stimulate the skin’s natural repair processes, you will begin to notice improvements in hydration, smoothness and firmness over the following days. Results continue to develop after the second treatment session, usually performed four weeks later.

With regular maintenance every six months, your skin will remain brighter, more elastic and naturally rejuvenated, while maintaining the soft, subtle and refreshed look that Profhilo is known for.

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Profhilo Frequently Asked Questions around Harley Street

Is Profhilo considered a medical or cosmetic treatment?

Profhilo is an injectable treatment delivered in a clinical setting. While cosmetic in purpose, it requires medical assessment to ensure suitability.

Who is typically a suitable candidate?

Profhilo is generally suitable for patients experiencing early skin laxity or dehydration who want improved firmness without adding volume.

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Where is Profhilo available?

Profhilo is performed at Dr Joney De Souza’s London clinic. Patients attend from Harley Street as well as nearby areas including Marylebone, Mayfair, Fitzrovia, and Bloomsbury.

Is Profhilo popular among Harley Street patients?

Many patients in the Harley Street area choose Profhilo for its structured, evidence-led approach to improving skin quality.

How does Profhilo differ from dermal fillers?

Fillers restore volume and structure. Profhilo stimulates collagen and elastin to improve hydration and elasticity without reshaping the face.

What is the usual treatment schedule?

Profhilo is typically delivered as two treatments spaced several weeks apart, followed by maintenance depending on individual response.

How soon will skin improvement be noticeable?

Hydration improvements may be noticeable within weeks, with continued enhancement as collagen production increases.

What if my skin laxity is more advanced?

If assessment suggests more structural support is required, alternative treatments may be discussed based on clinical indication.

 4.9 ★★★★★

Read our reviews

Our patients return to us year after year for natural, balanced results. Every review reflects our commitment to precision, safety and a personalised approach to aesthetic care.

I genuinely wouldn’t trust anyone else with my skin. Dr Joney de Souza remains my top recommendation for anyone seeking expert aesthetic care in London. He has a calm, professional manner and always takes the time to truly listen and understand what you’re hoping to achieve. His approach is natural and refined, you always leave looking like the best version of yourself, never overdone. The clinic is a beautiful, welcoming space in the heart of London, and the entire team is warm, knowledgeable, and highly professional. Dr Joney’s expertise and eye for detail are truly exceptional, and the results speak for themselves.
Daniele Bernardinetti
Daniele Bernardinetti
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I’ve known Dr. Joney de Souza for years and can’t recommend him highly enough. He’s a true expert in aesthetics — always professional, innovative, and genuinely caring. His treatments are subtle, natural, and always tailored to your needs. A standout in London’s aesthetic scene!
Osmar Pinheiro Bacelar Junior
Osmar Pinheiro Bacelar Junior
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I had treatment at Dr. Joney De Souza’s clinic one month ago and had a fantastic experience. Dr. De Souza was friendly, highly knowledgeable, and made me feel completely comfortable and at ease throughout the process. His great sense of humor also helped create a relaxed atmosphere. I’m really happy with the results and will definitely be coming back for regular visits. Highly recommend this clinic!
Daluna London
Daluna London
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The clinic is so very welcoming and really listens to how and what you would like to achieve, i have had several facial treatments and it has made such a difference to my confidence. David and everyone in the clinic are professional and experts in what they do, they treat you with a really personal service. My skin has never looked so clear or glowing .. I’ve had people stop and ask me what and where do I have my treatments .. thank you
Jayne Gates
Jayne Gates
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I had an excellent experience with Dr. Joney de Souza and his team. From start to finish, they were incredibly supportive, making me feel at ease throughout the entire process. Dr. Joney has both a sharp eye and a soft hand, striking the perfect balance between precision and gentleness. The team’s expertise speaks for itself, and their approach is as refined as it is reassuring. Highly recommended.

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How can you find us?

Our clinic is located in Marylebone, London, in the heart of one of Central London’s most prestigious and renowned medical districts. Perfectly positioned for convenience and discretion, we are easily accessible from across the capital and beyond.

We welcome patients from Mayfair, Harley Street, Marylebone, Knightsbridge, Belgravia, Chelsea, Kensington, Fitzrovia and St John’s Wood, as well as international patients visiting London for specialist treatment.

Our location benefits from excellent transport connections, with close proximity to major Underground stations, mainline rail links and direct access to Heathrow, Gatwick and London City airports. Several secure parking facilities and convenient chauffeur drop-off points are available nearby, ensuring a seamless and comfortable visit.

Whether you are travelling from elsewhere in London, across the UK or internationally, our clinic offers a calm, private and exclusive setting in one of the world’s leading medical destinations.

Opening hours
Monday
9 am–6 pm
Tuesday
9 am–6 pm
Wednesday
9 am–6 pm
Thursday
9 am–6 pm
Friday
9 am–6 pm
Saturday
Closed
Sunday
Closed
Dr Joney De Souza
49 Blandford St, London W1U 7HH
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Harley street - Profhilo for Skin Rejuvenation | Dr Joney De Souza