Profhilo is commonly recommended for patients in Harley Street experiencing reduced skin elasticity, fine textural changes, or early laxity who want improvement without volumising fillers. At Dr Joney De Souza’s London clinic, treatment planning is guided by anatomical assessment and realistic outcome discussion.
Profhilo Treatment Summary
Patients in the Harley Street area often prioritise treatments that improve skin integrity while maintaining natural facial proportions. Profhilo aligns with this approach because it enhances hydration and collagen stimulation rather than reshaping facial contours.
Instead of altering structure, Profhilo supports skin quality at a cellular level. This makes it suitable for individuals who want subtle improvement in firmness and elasticity without augmentation.
Consultation focuses on skin condition, ageing patterns, and suitability before treatment proceeds.
Profhilo contains a stabilised, high concentration of hyaluronic acid formulated to diffuse through the skin after injection. Once administered at specific points, it stimulates collagen and elastin production, improving skin firmness and texture over time.
Treatment is commonly performed on:
Face
Neck
Décolletage
Hands
Because Profhilo works through bioremodelling rather than filling, it is often selected for patients who want overall skin improvement rather than contour change.
Patients are encouraged to review the main Profhilo treatment information page for detailed explanation of technique and suitability.

The clinic is conveniently located near Harley Street and easily accessible on foot or via nearby Underground stations such as Regent’s Park, Oxford Circus, or Bond Street.
Given the minimal downtime associated with Profhilo, Harley Street patients often schedule treatment during regular working weeks without extended recovery planning.

If you’re considering Profhilo in the Harley Street area, consultation is essential to determine whether the treatment aligns with your skin condition and expectations. During this appointment, Dr Joney will take time to understand your skin goals, assess your hydration levels, elasticity and overall skin quality, and identify the areas that will benefit most from treatment. He will explain how Profhilo works, what improvements you can expect, and whether combining it with other treatments may help achieve optimal results.
Once your personalised plan is agreed, the skin is gently cleansed and a topical anaesthetic may be applied to ensure comfort. Using precise injection techniques, Dr Joney administers small amounts of Profhilo into a series of bio-aesthetic points just beneath the skin. The treatment is quick and designed to distribute the hyaluronic acid evenly across the tissue, stimulating collagen and elastin for a naturally refreshed, hydrated and lifted appearance. Discomfort is minimal and there is no significant downtime.
Following your Profhilo treatment, you can return to most daily activities straight away. You may notice slight redness, swelling or small visible bumps at the injection sites. These are completely normal and typically disappear within a few hours to 24 hours as the product begins to disperse through the skin.
Dr Joney will provide personalised aftercare advice, which may include avoiding strenuous exercise, heat treatments and applying pressure to the treated areas for 24 to 48 hours. As the active ingredients stimulate the skin’s natural repair processes, you will begin to notice improvements in hydration, smoothness and firmness over the following days. Results continue to develop after the second treatment session, usually performed four weeks later.
With regular maintenance every six months, your skin will remain brighter, more elastic and naturally rejuvenated, while maintaining the soft, subtle and refreshed look that Profhilo is known for.


Profhilo is an injectable treatment delivered in a clinical setting. While cosmetic in purpose, it requires medical assessment to ensure suitability.
Profhilo is generally suitable for patients experiencing early skin laxity or dehydration who want improved firmness without adding volume.
Profhilo is performed at Dr Joney De Souza’s London clinic. Patients attend from Harley Street as well as nearby areas including Marylebone, Mayfair, Fitzrovia, and Bloomsbury.
Many patients in the Harley Street area choose Profhilo for its structured, evidence-led approach to improving skin quality.
Fillers restore volume and structure. Profhilo stimulates collagen and elastin to improve hydration and elasticity without reshaping the face.
Profhilo is typically delivered as two treatments spaced several weeks apart, followed by maintenance depending on individual response.
Hydration improvements may be noticeable within weeks, with continued enhancement as collagen production increases.
If assessment suggests more structural support is required, alternative treatments may be discussed based on clinical indication.
Our patients return to us year after year for natural, balanced results. Every review reflects our commitment to precision, safety and a personalised approach to aesthetic care.

Our team would love to hear from you. Whether you have questions, need guidance, or simply want to explore your treatment options, we’re here to support you every step of the way. If you would like to place an online booking you can do this via our online booking system.
Dr Joney De Souza Skin and Laser Clinic is located in central Marylebone and is easily accessible by public transport or car, with Bond Street, Oxford Circus and Baker Street Underground stations all just a short walk away. For those driving, paid on-street parking and nearby public car parks are available, making the clinic convenient to reach from across London, including Mayfair and Soho.