
Stimulate collagen, restore skin quality and rejuvenate the face with JULÄINE™ treatment in Marylebone, London. A refined, doctor-led collagen biostimulator designed for progressive, natural-looking rejuvenation.
Gradual, natural-looking skin improvement with a Swedish-engineered PLLA formula
Julaine treatment in London suits patients who prefer gradual collagen improvement over immediate volume change. At Dr Joney De Souza Clinic in Marylebone, patients most commonly choose Julaine biostimulator treatment for:
Many patients booking Julaine treatment in London have tried hyaluronic acid fillers and want a different approach. Others arrive at the first signs of collagen loss, wanting to address it early with a more regenerative strategy.
Julaine is a next-generation PLLA-based collagen biostimulator, developed by Nordberg Medical in Sweden. It stimulates the body’s own collagen production over time, improving skin firmness, quality and facial support gradually. Unlike hyaluronic acid fillers, Julaine does not add immediate volume. Instead, it encourages the skin’s biological processes to rebuild collagen from within. Results develop progressively over four to twelve weeks. In practice, improvements in firmness, skin quality and texture continue to build over several months.
Dr Joney De Souza performs Julaine biostimulator treatment in London at his Marylebone clinic. With over 20 years in aesthetic medicine, Dr De Souza assesses each patient carefully before recommending Julaine treatment. His approach is conservative and anatomy-focused, ensuring the plan suits your skin condition, facial structure and long-term goals.
Julaine contains poly-L-lactic acid (PLLA), a biocompatible material that biodegrades safely over time. When injected into the skin, it stimulates fibroblasts to produce new collagen, gradually rebuilding the skin’s structural support. Results are not immediate. However, over four to twelve weeks, improvements in firmness, skin quality and texture become visible. In practice, most patients benefit from two to three sessions spaced four to eight weeks apart to achieve the full result.
At your consultation, Dr De Souza assesses your skin quality, facial structure and degree of collagen loss. He reviews your medical history and discusses your aesthetic goals in detail. As a result, he confirms whether Julaine biostimulator treatment is appropriate and outlines a personalised treatment plan. Additionally, he explains how many sessions he recommends and what results you can realistically expect.
Before treatment begins, Dr De Souza cleanses the skin thoroughly. He then applies a topical anaesthetic cream to the treatment area and allows time for it to take full effect. Additionally, he marks the injection points based on your anatomy and the treatment plan agreed at consultation, ensuring precise and consistent product placement.
Dr De Souza injects the Julaine solution into the skin using fine needles or a cannula, depending on the treatment area. He distributes the product evenly to support uniform collagen stimulation across the targeted zone. Overall, the injection phase takes around 20 to 30 minutes, followed by a brief post-injection massage.
After treatment, you can return to your normal activities immediately. In most cases, mild swelling, redness or tenderness at the injection sites resolves within 24 to 48 hours. Additionally, Dr De Souza advises patients to massage the treated area as instructed, to ensure an even distribution of the product and reduce the risk of nodule formation.
Julaine results are not visible immediately after treatment. In practice, collagen stimulation builds progressively over four to twelve weeks. Furthermore, improvements in skin firmness and quality continue to develop over the following months as new collagen forms gradually.
Most patients benefit from two to three sessions of Julaine treatment, spaced four to eight weeks apart. However, the exact number depends on your degree of collagen loss, skin condition and treatment goals. Dr De Souza discusses the full treatment plan and session schedule at your initial consultation.
Julaine is typically delivered as a course of three sessions, spaced four to six weeks apart. Dr De Souza plans your schedule at consultation based on your anatomy, skin quality and treatment goals, then reviews your progress before each session to refine the injection approach as your collagen response develops. Over the full course, results build gradually, with the final outcome continuing to mature for several months after your last session.

Dr Joney De Souza is a highly experienced aesthetic doctor based in Marylebone, London. With over 20 years of practice, he brings a thorough understanding of facial anatomy, skin biology and collagen-stimulating treatments to every patient he assesses. His approach is conservative and personalised, with a focus on results that look natural rather than obvious.
Dr Joney De Souza Clinic prices Julaine treatment per session. Pricing reflects the expertise of the treating doctor, the quality of the product and the personalised assessment and planning included in every booking. During your consultation, Dr De Souza confirms the recommended number of sessions and builds your full treatment plan.
In practice, most patients benefit from two to three Julaine sessions to achieve the best collagen response. However, the exact number depends on your degree of collagen loss, skin condition and goals. Dr De Souza discusses this at your initial consultation, so you can plan and budget clearly from the start.
| Treatment | Price (£) |
|---|---|
JULÄINE™ | 1,300 |
Sculptra is a well-established PLLA-based collagen biostimulator that Dr Joney De Souza also offers at his London clinic. Like Julaine, Sculptra works by stimulating the body’s own collagen production over time. However, the two treatments have different formulations and may suit different patients depending on anatomy, degree of collagen loss and treatment goals.
If you are uncertain whether Julaine or Sculptra is the better fit for your concerns, Dr De Souza can discuss both options at your consultation. Furthermore, the clinic’s dedicated Sculptra London page covers the treatment in full detail. Additionally, a Julaine vs Sculptra comparison page is available for patients who want a side-by-side overview before booking.

Below you will find answers to the most common questions about Julaine treatment. For personalised advice, contact the team at Dr Joney De Souza Clinic in Marylebone.
Julaine is a PLLA-based collagen biostimulator developed by Nordberg Medical in Sweden. It stimulates the body’s own collagen production when Dr De Souza injects it into the skin, gradually improving firmness, skin quality and facial support over several weeks and months. In practice, results continue to build for up to twelve weeks after each session.
Dr De Souza commonly uses Julaine to treat the cheeks, temples, jawline and mid-face. In some cases, it also suits the lower face and neck. However, the appropriate treatment areas depend on your anatomy and goals, which Dr De Souza confirms at consultation.
Most patients need two to three Julaine sessions to achieve the best result. In practice, Dr De Souza spaces sessions four to eight weeks apart to allow each treatment to take full effect. He confirms the recommended plan at your initial consultation based on your skin condition and goals.
Julaine results can last up to two years or longer, depending on your skin response, lifestyle and the number of sessions completed. In most cases, a maintenance session supports the result at the appropriate time. Dr De Souza reviews your progress at follow-up appointments and advises on timing.
No. Julaine is a collagen biostimulator, not a traditional hyaluronic acid filler. It does not create immediate volume. Instead, it stimulates the skin to produce new collagen gradually over several weeks, resulting in improvements that look completely natural.
Both Julaine and Sculptra use PLLA to stimulate collagen. However, they are different products with distinct formulations and treatment characteristics. Dr De Souza discusses which is more appropriate for your anatomy and goals during your consultation. Additionally, the clinic offers a detailed Julaine vs Sculptra comparison page for patients who want to understand both options in full.
Julaine treatment suits adults with early-to-moderate signs of collagen loss, skin laxity or reduced skin quality who prefer a gradual and natural-looking result. In practice, Dr De Souza assesses full suitability at a face-to-face consultation, reviewing your medical history, skin condition and treatment goals.
Most patients describe mild pressure and a brief sting with each injection point. In practice, Dr De Souza applies topical anaesthetic cream beforehand to reduce any discomfort. Overall, the majority of patients tolerate the procedure well and report it as manageable.
After Julaine, avoid intense exercise, saunas, alcohol and direct sun exposure for 24 to 48 hours. Additionally, Dr De Souza advises patients to massage the treated area gently as instructed, to support even distribution of the product and reduce the risk of nodule formation. In most cases, normal daily activities are possible on the same day.
Yes, Julaine biostimulator treatment can often complement other procedures. Dr De Souza may recommend combining it with polynucleotides for skin repair, Profhilo for hydration, or Morpheus8 for tissue tightening, depending on your goals. However, the timing and sequence of combined treatments require careful planning to avoid over-treatment.
No. Julaine biostimulator treatment is not suitable during pregnancy or breastfeeding. Additionally, Dr De Souza does not recommend it for patients with active skin infections, certain autoimmune conditions or a history of keloid scarring in the treatment area. Suitability is always confirmed at a full medical consultation before any treatment begins.
Below you will find answers to common questions about Julaine costs, how it compares with other treatments, and safety considerations relevant to this treatment.
Julaine treatment in London at Dr Joney De Souza Clinic costs £1,300 per session. In practice, most patients need two to three sessions for the best result. Dr De Souza outlines the full plan and total cost at your initial consultation.
For patients with early-to-moderate collagen loss who want gradual, natural-looking improvement, Julaine biostimulator treatment offers a long-term result that can last up to two years. However, value depends on your individual goals and anatomy, which Dr De Souza discusses openly at your consultation. In practice, patients who commit to a full course consistently report visible and satisfying results.
Profhilo is a hyaluronic acid skin booster that primarily improves skin hydration and quality. Julaine, by contrast, is a PLLA biostimulator that stimulates new collagen production for longer-term structural improvement. In some cases, Dr De Souza recommends combining both treatments as part of a regenerative programme, addressing hydration and collagen support together.
Neither treatment is universally better. Julaine and Sculptra are both PLLA-based biostimulators with different formulations and clinical applications. In practice, Dr De Souza recommends the most appropriate option based on your specific anatomy, collagen status and goals. Furthermore, some patients may suit a combination of both approaches.
Yes, in many cases. Polynucleotides support skin repair and regeneration at a cellular level, while Julaine stimulates new collagen production for structural improvement. Dr De Souza can design a combined regenerative programme at your consultation if this approach suits your goals and skin condition.
PLLA stands for poly-L-lactic acid. It is a biocompatible, biodegradable material that clinicians have used safely in aesthetic medicine for many years. Additionally, PLLA has a long history of use in medical applications including dissolvable sutures, supporting its well-established safety profile in the body.
Common side effects include temporary swelling, redness or bruising at the injection sites, which typically settle within 24 to 48 hours. In rare cases, nodules or other tissue reactions can occur. Dr De Souza discusses all risks, contraindications and aftercare instructions fully at your consultation.
Dermal fillers, typically made from hyaluronic acid, add immediate volume to specific areas of the face. Julaine, by contrast, stimulates the body to produce its own collagen over several weeks. As a result, changes from Julaine develop gradually and structurally rather than as an immediate visible change. In practice, patients looking for instant results are better suited to fillers than to biostimulators.
In many cases, yes. However, the timing, amount and location of previous filler treatments can influence the Julaine treatment plan. Dr De Souza reviews your full treatment history at your consultation before recommending Julaine biostimulator treatment and advises whether any waiting period is appropriate.
You can book a Julaine consultation with Dr Joney De Souza at his Marylebone clinic via the Book Online button on this page, or by sending a WhatsApp message to the clinic. During the consultation, Dr De Souza assesses your suitability and outlines a personalised treatment plan. Additionally, you can call the clinic directly to arrange your appointment.
I had my first Julaine session with Dr De Souza six weeks ago and I am already noticing a real improvement in my skin firmness and texture. The results are subtle and completely natural-looking. Dr De Souza was thorough in explaining how the treatment works and what to expect. I feel much more confident in my skin and have already booked my second session.
After researching Julaine treatment in London for several months, I chose Dr Joney De Souza based on his reviews and experience. The consultation was genuinely informative and he took time to explain the collagen stimulation process properly. Three months after my treatment, the improvement in my skin quality is clearly visible and I have had several comments about how refreshed I look.
I had Julaine treatment at Dr De Souza’s Marylebone clinic and the experience from start to finish was excellent. The aftercare advice was clear and the swelling settled within a day. Over the following weeks my skin gradually looked firmer and more radiant. I would absolutely recommend Dr De Souza for anyone considering Julaine treatment in London.