PRP with SkinPen microneedling at Dr Joney De Souza in Marylebone, London. Doctor-led treatment for acne scars, texture and skin renewal. From £490.
If acne scarring, tired-looking skin or rough texture is holding your complexion back, PRP with SkinPen microneedling is designed to rebuild your skin from within. It suits patients at Dr Joney De Souza Skin & Laser in Marylebone who want a genuine improvement in skin quality without surgery or heavy resurfacing. We most often recommend it for:
It is worth being clear about what this treatment will not do. It softens scars and refines texture, so it is not a filler and will not restore lost facial volume or lift a heavily sagging jawline. If your main concern is deep volume loss, a treatment such as dermal fillers may suit you better, and your practitioner will tell you honestly at your consultation.
PRP with SkinPen microneedling is a combination treatment that pairs medical-grade SkinPen microneedling with platelet-rich plasma (PRP) drawn from your own blood. SkinPen creates thousands of precise micro-channels in the skin, and the concentrated growth factors in your PRP are then delivered into those channels to accelerate healing and collagen renewal. It uses your body’s own plasma, which fits Dr De Souza’s philosophy of natural, refined results, and it is often searched for as a “vampire facial”.
Every result below is a real Dr Joney De Souza patient. Use the slider to see the change. Results vary from person to person.
Skinpen Treatment
Skinpen Treatment
PRP treatment
PRP treatment
The treatment works in two complementary steps. A small sample of your blood is drawn and spun in a centrifuge to concentrate the platelets and growth factors into platelet-rich plasma. The SkinPen device then passes over the treatment area, creating controlled micro-channels that trigger the skin’s natural wound-healing response and stimulate collagen and elastin. Those open channels let the PRP growth factors penetrate far deeper than they could on the surface, driving a stronger regenerative response than microneedling alone.
PRP, or platelet-rich plasma, is made from a small sample of your own blood. The blood is spun in a centrifuge to separate and concentrate the platelets and their growth factors, the signals your body uses to repair and regenerate tissue. It comes from you, so the risk of an allergic reaction is very low.
SkinPen is a medical-grade microneedling device that creates thousands of controlled micro-channels in the skin. This triggers the body’s natural wound-healing response, prompting fresh collagen and elastin to form, which firms and smooths the skin over the following weeks.
The micro-channels created by SkinPen let the concentrated PRP growth factors penetrate far deeper than they could if simply applied to the surface. The combination drives a stronger regenerative response than microneedling alone, and it is especially useful for acne scarring and more advanced textural concerns.
Yes. A small sample is drawn at the start of your appointment and prepared on-site while your skin is numbed. The plasma is autologous, meaning it comes from your own body, so it integrates naturally and carries a very low risk of reaction, which is a key part of why the treatment is so well tolerated.
Standalone SkinPen stimulates collagen through micro-channels alone, while the combination adds your own platelet-rich plasma for an extra growth-factor boost. That extra stimulation makes the combination a popular choice for acne scarring and advanced texture, and standalone microneedling remains a strong option for general skin quality.
A topical numbing cream is applied before microneedling, so most patients feel only light pressure and a mild prickling sensation. Any tenderness afterwards is usually brief and settles within a day or two, similar to mild sunburn.
From first consultation to final review, your treatment at our Marylebone clinic follows a clear, doctor-led path. Results build gradually as collagen renews, so most patients benefit from a short course of sessions spaced several weeks apart.
Your practitioner carries out a detailed skin assessment at the Marylebone clinic and takes a full medical history to confirm you are suitable. On the day, we ask you to arrive without heavy make-up. The skin is cleansed, a small blood sample is drawn for your PRP, and a topical numbing cream is applied for around 20 to 30 minutes while the plasma is prepared.
Once the skin is numb, your practitioner passes the SkinPen device across the treatment area to create the micro-channels, then applies your prepared PRP so the growth factors absorb deep into the skin. Most sessions take around 60 to 75 minutes in total, including preparation, and the sensation is typically a light prickling that is well tolerated.
The skin looks flushed and feels warm, similar to mild sunburn, for the first 24 to 72 hours, and may feel slightly tight or dry as it heals. The team provides a tailored aftercare routine built around gentle moisturisers and daily SPF50, since fresh collagen is vulnerable to UV. A review appointment lets your practitioner track your progress and plan any maintenance.
PRP involves drawing and processing your own blood, so it should be carried out under strict medical protocols, not in a salon setting. At Dr Joney De Souza in Marylebone, every treatment is doctor-led from assessment through to review. Carried out by one of our doctors, Dr Joney De Souza or Dr Mattia Parducci. Your consultation is with Dr Joney De Souza or Dr Mattia Parducci.
“My ‘less is more’ approach has become the mainstay of my practice and clients appreciate that they will have natural looking results” Dr Joney De Souza, The Sybarite
By working with your own growth factors to stimulate the skin’s own collagen, this is care with skin longevity in mind, supporting the strength and quality of your skin over time.
PRP with SkinPen microneedling starts from £490 per session for one area, such as the full face. It is a combination treatment, so the final price depends on the number of areas treated and the number of sessions in your plan. Standalone SkinPen microneedling, without PRP, is available separately from £450. Most patients are guided towards a short course for the strongest collagen response, and course pricing offers the best value.
The prices below are for treatment with an associate clinician. Your exact plan and final investment are always confirmed at your personal consultation.
| Treatment | Single (£) | Course of 2 (£) |
|---|---|---|
PRP with SkinPen, 1 area (e.g. face) | 490 | 830 |
PRP with SkinPen, 2 areas | 660 | , |
PRP with SkinPen sits within Dr Joney De Souza’s wider range of regenerative and microneedling treatments. If you prefer a simpler protocol, standalone SkinPen microneedling stimulates collagen through micro-channels alone, while PRP and PRF can also be used on their own for the face, or for hair loss. If you are chasing a stronger result for deeper scarring, exosome treatment is another regenerative option. Your practitioner will help you choose the right treatment, or the right combination, at your consultation.
Below are the questions patients most often ask about PRP with SkinPen microneedling in Marylebone. Every skin is different, so the guidance below is general, and your personalised plan is confirmed at your assessment.
At Dr Joney De Souza Skin & Laser in Marylebone, London, PRP with SkinPen microneedling is a combination treatment that pairs medical-grade microneedling with platelet-rich plasma drawn from your own blood. SkinPen creates precise micro-channels in the skin, and the concentrated growth factors in the PRP are then delivered into those channels to accelerate healing and regeneration. It uses your body’s own plasma, which aligns with Dr De Souza’s philosophy of natural, refined results.
The two work on the skin in different, complementary ways. SkinPen microneedling triggers the natural wound-healing response and stimulates collagen and elastin, while the micro-channels it opens let PRP growth factors penetrate deeper than they would on their own. The combination drives a stronger regenerative response than microneedling alone and improves texture, tone and firmness more consistently. Patients with acne scarring or textural irregularities tend to see the clearest benefit from combining the two.
A course of three sessions spaced several weeks apart is usually recommended for the best collagen response. The exact number depends on your skin condition and goals, which your practitioner confirms at your consultation. Results are progressive, so many patients then return for occasional maintenance sessions to sustain the improvement.
Most patients experience mild redness, sensitivity and slight swelling for one to three days, similar to mild sunburn. The skin may feel tight or slightly dry during the healing phase. Most people return to normal activities within 24 to 72 hours, and the sensitivity period usually settles within three to five days.
Results are progressive rather than instant, because the treatment works at a deeper biological level than a surface facial. Collagen production builds over several weeks, so skin gradually looks smoother, clearer and firmer. Results typically last six to twelve months depending on your skin and your maintenance routine.
At Dr Joney De Souza, PRP for the face starts from £490 per session, and a standalone SkinPen microneedling course for the face starts from £450. This is a combination treatment, so the final price depends on the areas treated and the number of sessions in your plan. Your practitioner confirms an exact quote at your consultation once your goals are agreed. You can view the full breakdown on our prices page.
Standalone SkinPen microneedling stimulates collagen through micro-channels alone, while the combination adds your own platelet-rich plasma to boost the regenerative response. That extra growth-factor stimulation makes the combination a popular choice for acne scarring and more advanced textural concerns. If you prefer a simpler protocol, our standalone SkinPen microneedling page explains that option in full.
Performed in a doctor-led clinical environment, PRP with SkinPen microneedling is considered safe and well tolerated, and the PRP is derived from your own blood, so the risk of allergic reaction is very low. The treatment is carried out by one of our doctors, Dr Joney De Souza or Dr Mattia Parducci. Your consultation is with Dr Joney De Souza or Dr Mattia Parducci. It is performed at the Marylebone clinic, not in a salon setting, because it involves drawing and processing your own blood under strict medical protocols. A full medical history is taken at consultation to confirm you are suitable.
Patients return to Dr Joney De Souza year after year for natural, balanced results. Every review reflects our commitment to precision, safety and a personalised approach to skin and laser care in Marylebone.
I highly recommend Dr. Joney and his clinic. I have been his patient for many years and he is definitely one of the best. His work is natural and subtle, he always puts the patient’s interest first and will never try to upsell unnecessary treatments.
Had an excellent experience today getting the Profhilo treatment done by Dr. Joney De Souza. The entire team was so friendly, and prepped me about what I should expect during and after the treatment.
Dr Joney is the most wonderful Dr, kind and caring and highly experienced. I feel safe in his care and trust his opinion 100%.
