Profhilo is commonly chosen by Marylebone patients who notice early skin laxity, dullness, or crepiness and want to improve hydration and collagen stimulation without adding volume. At Dr Joney De Souza’s London clinic, Profhilo is recommended following careful skin assessment and discussion of realistic outcomes.
Profhilo Treatment Summary
Many patients in Marylebone prioritise long-term skin health. They may feel their skin looks tired or less firm, yet they do not want fillers or structural lifting.
Profhilo works differently from traditional dermal fillers. Instead of adding volume, it spreads within the skin to stimulate collagen and elastin production. This makes it suitable for individuals seeking improved texture, hydration, and overall skin quality.
Treatment is typically performed as a course, allowing gradual improvement rather than immediate visible change.
Profhilo is an injectable treatment containing high-concentration hyaluronic acid designed to improve skin hydration and elasticity. It is administered at specific points to allow even diffusion across the treated area.
Common treatment areas include:
Face
Neck
Décolletage
Hands
Improvements develop progressively over several weeks as collagen and elastin production increase. Because the treatment focuses on bioremodelling rather than augmentation, facial contours remain natural.
For detailed technical information, patients are encouraged to review the main Profhilo treatment information page.

The clinic is conveniently located for Marylebone residents and professionals. Many patients attend on foot or via nearby stations such as Baker Street, Regent’s Park, or Bond Street.
Given the minimal downtime associated with Profhilo, Marylebone patients often schedule treatment during working weeks without significant disruption.

If you’re based in Marylebone and considering Profhilo, consultation is essential to assess skin condition and determine whether treatment is appropriate. During this appointment, Dr Joney will take time to understand your skin goals, assess your hydration levels, elasticity and overall skin quality, and identify the areas that will benefit most from treatment. He will explain how Profhilo works, what improvements you can expect, and whether combining it with other treatments may help achieve optimal results.
Once your personalised plan is agreed, the skin is gently cleansed and a topical anaesthetic may be applied to ensure comfort. Using precise injection techniques, Dr Joney administers small amounts of Profhilo into a series of bio-aesthetic points just beneath the skin. The treatment is quick and designed to distribute the hyaluronic acid evenly across the tissue, stimulating collagen and elastin for a naturally refreshed, hydrated and lifted appearance. Discomfort is minimal and there is no significant downtime.
Following your Profhilo treatment, you can return to most daily activities straight away. You may notice slight redness, swelling or small visible bumps at the injection sites. These are completely normal and typically disappear within a few hours to 24 hours as the product begins to disperse through the skin.
Dr Joney will provide personalised aftercare advice, which may include avoiding strenuous exercise, heat treatments and applying pressure to the treated areas for 24 to 48 hours. As the active ingredients stimulate the skin’s natural repair processes, you will begin to notice improvements in hydration, smoothness and firmness over the following days. Results continue to develop after the second treatment session, usually performed four weeks later.
With regular maintenance every six months, your skin will remain brighter, more elastic and naturally rejuvenated, while maintaining the soft, subtle and refreshed look that Profhilo is known for.


Profhilo improves skin hydration and elasticity without adding volume or reshaping facial contours. Fillers, by contrast, are used to restore structure or projection.
Many Marylebone patients choose Profhilo when they want subtle skin improvement without visible change to facial shape.
Profhilo is performed at Dr Joney De Souza’s London clinic. Patients attend from Marylebone as well as nearby areas including Harley Street, Mayfair, Fitzrovia, and Bloomsbury.
Profhilo is typically administered as two treatments spaced several weeks apart, though this may vary depending on skin condition.
Most patients experience minimal downtime, with small injection marks settling quickly.
Yes, many Marylebone patients return to work shortly after treatment, as recovery is generally minimal.
Profhilo does not function as a lifting treatment. It improves skin firmness and elasticity, which may give a fresher appearance over time.
In some cases, Profhilo is incorporated into a broader skin plan. Combination approaches are discussed during consultation to ensure suitability.
Our patients return to us year after year for natural, balanced results. Every review reflects our commitment to precision, safety and a personalised approach to aesthetic care.

Our team would love to hear from you. Whether you have questions, need guidance, or simply want to explore your treatment options, we’re here to support you every step of the way. If you would like to place an online booking you can do this via our online booking system.
Dr Joney De Souza Skin and Laser Clinic is located in central Marylebone and is easily accessible by public transport or car, with Bond Street, Oxford Circus and Baker Street Underground stations all just a short walk away. For those driving, paid on-street parking and nearby public car parks are available, making the clinic convenient to reach from across London, including Mayfair and Soho.