Profhilo is frequently chosen by Mayfair patients who notice reduced skin elasticity, fine textural changes, or dullness and want improvement without volumising treatments. At Dr Joney De Souza’s London clinic, Profhilo is recommended following personalised consultation and careful skin assessment.
Profhilo Treatment Summary
Many Mayfair patients prefer treatments that refine rather than reshape. Profhilo supports this approach by stimulating collagen and elastin production without changing facial contours.
Rather than adding projection or volume, Profhilo improves hydration and skin integrity from within. This makes it suitable for patients who want their skin to appear fresher and firmer without visible intervention.
Treatment is usually performed as a short course, allowing results to develop gradually and naturally.
Profhilo contains high-concentration hyaluronic acid formulated to diffuse across the skin after injection. Once administered at carefully selected points, it stimulates the skin’s natural collagen and elastin production.
It is commonly used for:
Facial skin laxity
Neck crepiness
Décolletage texture
Hand rejuvenation
Because Profhilo works on skin quality rather than structure, it can complement other treatments without altering facial proportions.
For detailed clinical information, patients can review the main Profhilo treatment information page.

The clinic is easily accessible from Mayfair via Green Park, Bond Street, or Marble Arch. Many patients attend by car or taxi to maintain privacy.
Given the minimal downtime associated with Profhilo, appointments are often scheduled around professional commitments without extended recovery planning.

If you’re based in Mayfair and considering Profhilo, consultation will determine whether the treatment aligns with your skin concerns and expectations. During this appointment, Dr Joney will take time to understand your skin goals, assess your hydration levels, elasticity and overall skin quality, and identify the areas that will benefit most from treatment. He will explain how Profhilo works, what improvements you can expect, and whether combining it with other treatments may help achieve optimal results.
Once your personalised plan is agreed, the skin is gently cleansed and a topical anaesthetic may be applied to ensure comfort. Using precise injection techniques, Dr Joney administers small amounts of Profhilo into a series of bio-aesthetic points just beneath the skin. The treatment is quick and designed to distribute the hyaluronic acid evenly across the tissue, stimulating collagen and elastin for a naturally refreshed, hydrated and lifted appearance. Discomfort is minimal and there is no significant downtime.
Following your Profhilo treatment, you can return to most daily activities straight away. You may notice slight redness, swelling or small visible bumps at the injection sites. These are completely normal and typically disappear within a few hours to 24 hours as the product begins to disperse through the skin.
Dr Joney will provide personalised aftercare advice, which may include avoiding strenuous exercise, heat treatments and applying pressure to the treated areas for 24 to 48 hours. As the active ingredients stimulate the skin’s natural repair processes, you will begin to notice improvements in hydration, smoothness and firmness over the following days. Results continue to develop after the second treatment session, usually performed four weeks later.
With regular maintenance every six months, your skin will remain brighter, more elastic and naturally rejuvenated, while maintaining the soft, subtle and refreshed look that Profhilo is known for.


Yes. Profhilo is often selected by Mayfair patients who want improved firmness and hydration without altering facial contours.
For many patients, yes. Profhilo involves minimal visible change and little downtime, making it suitable for those who prefer understated treatment.
Profhilo is carried out at Dr Joney De Souza’s London clinic. Patients attend from Mayfair as well as nearby areas including Marylebone, Harley Street, Fitzrovia, and Soho.
Profhilo is typically administered as two treatments spaced several weeks apart, with maintenance depending on skin response.
No. Profhilo improves skin hydration and elasticity but does not add structure or projection.
Yes. Many Mayfair patients book Profhilo during regular working periods due to the minimal recovery time required.
Skin hydration may improve within weeks, with continued enhancement in firmness as collagen production increases.
In some cases, Profhilo forms part of a broader skin quality plan. Combination approaches are discussed during consultation.
Our patients return to us year after year for natural, balanced results. Every review reflects our commitment to precision, safety and a personalised approach to aesthetic care.

Our team would love to hear from you. Whether you have questions, need guidance, or simply want to explore your treatment options, we’re here to support you every step of the way. If you would like to place an online booking you can do this via our online booking system.
Dr Joney De Souza Skin and Laser Clinic is located in central Marylebone and is easily accessible by public transport or car, with Bond Street, Oxford Circus and Baker Street Underground stations all just a short walk away. For those driving, paid on-street parking and nearby public car parks are available, making the clinic convenient to reach from across London, including Mayfair and Soho.