
At Dr Joney De Souza Skin & Laser in Marylebone, London, patients often ask which anti-wrinkle treatments actually work, and which one is right for them. It is a fair question, because the choices have grown. The honest answer is that the best anti-wrinkle treatment depends on your lines, your skin and your goals. Below, our team explains the main options, from anti-wrinkle injections to collagen-boosting and laser treatments, so you can choose with confidence.
Anti-wrinkle injections are a popular, non-surgical way to soften expression lines. A doctor places small amounts of a prescription muscle-relaxing medicine into specific facial muscles. As those muscles relax, the lines above them ease. Typically, the areas treated are the forehead, the frown lines between the brows, and the crow’s feet around the eyes. You can read more on our anti-wrinkle injections page.
Expression lines form as muscles contract over many years. By gently relaxing these muscles, the skin above them creases less. As a result, the face looks smoother and more rested, while still moving naturally. Results usually appear within a few days and settle by around two weeks, then last roughly three to four months before a top-up is needed.
Understanding your lines helps you choose. Dynamic lines appear when you move your face, for example when you frown or smile. Static lines, by contrast, are visible even at rest. Because they have different causes, they respond to different treatments:
For deeper, settled creases, injections alone may not be enough. In these cases, treatments that rebuild collagen often help.
Some anti-wrinkle treatments work by improving the skin itself. Injectable skin boosters and treatments such as Profhilo add deep hydration and stimulate collagen. Over time, this can soften fine lines and restore a healthy glow. They also pair well with injections for a natural result. You can read more about skin boosters on our site.
Laser resurfacing takes a different route. By renewing the skin’s surface, it smooths fine lines, sun damage and uneven texture. Treatments such as CO2 laser and Endolift can firm and refine the skin. Your clinician then advises whether laser suits your skin type and your lines.
There is no single best anti-wrinkle treatment. Instead, the right choice depends on your lines, your skin and your goals. Frequently, a combination works better than one treatment alone. For this reason, a doctor-led consultation is the surest way to decide, because it lets us tailor a plan to your face.
In experienced hands, these treatments have a strong safety record. Even so, they are medical procedures and are not suitable for everyone. We do not treat during pregnancy or breastfeeding, or over active skin infections. Certain medical conditions may also rule treatment out. A consultation reviews your health and suitability first, and keeps your result natural and safe.
Ready to find out which anti-wrinkle treatment suits your skin? Book a consultation with the team at Dr Joney De Souza in Marylebone, where we assess your concerns and design a personalised plan. You can also review treatment costs on our prices page before you decide.
Unsure whether anti-wrinkle injections, collagen-boosting treatments or laser resurfacing is right for your lines? The team at Dr Joney De Souza in Marylebone will assess your skin honestly and recommend a tailored plan. Book a consultation today to discuss your concerns, understand what results you might expect, and view clear, upfront pricing before you commit.

Common questions our Marylebone team hears.
Anti-wrinkle treatments are non-surgical ways to soften lines, including anti-wrinkle injections, collagen-boosting injectables, and laser resurfacing.
Anti-wrinkle injections relax the muscles that create expression lines, while dermal fillers add volume and smooth static lines. They are often used together.
Results usually last three to four months. With regular maintenance, many patients find the effect becomes easier to sustain over time.
Most people feel only a small pinch. The appointment is quick, and no anaesthetic is usually needed.
Downtime is minimal. Some patients have tiny bumps or mild redness for a short time, and most return to normal activities straight away.
They work best on dynamic lines, such as forehead lines, frown lines between the brows, and crow’s feet around the eyes.
Lines visible at rest often respond better to collagen-boosting treatments or laser resurfacing, sometimes combined with injections.
In experienced, doctor-led hands they have a strong safety record. They remain medical procedures, so a consultation checks your suitability first.
Many people notice a change within a few days, with the full effect usually visible around two weeks after treatment.
A doctor-led consultation assesses your lines, skin and goals, then recommends the most suitable treatment or combination for you.