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Anti-wrinkle Treatments with Dr Joney De Souza

Discover expert anti-wrinkle injection treatments in Marylebone with Dr Joney De Souza.

Prevention is often better than the cure

Anti-wrinkle Treatment Summary

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No. of treatments
up to 3 areas may be treated during one session
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Procedure time
30 minutes
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Back to work
Straight away
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Duration of results
3–6 months
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Anaesthetic
Topical
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Sensitivity period
None
Price From
£375
*Prices vary based on number of treatment areas. View our full pricing information below.

anti-wrinkle injection treatments in Marylebone, London

Smooth and refine fine lines with anti-wrinkle injections

Anti-wrinkle Injections are the most effective treatment for lines and wrinkles that appear with facial expression (also known as dynamic lines). At Dr Joney De Souza Clinic we favour a clinically proven product as we believe this is the best and long lasting treatment giving excellent results. We always select the very best products and technologies without compromise.

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Prevention is often the primary factor

Anti-wrinkle injections have become one of the most trusted and widely used treatments for softening expression lines and maintaining a fresher, more relaxed appearance. Increasingly, people are choosing to start treatment earlier as a preventative approach, addressing fine lines before they become deeply set.

Rather than altering facial shape or expression, anti-wrinkle injections work by calming the overactive muscles that contribute to frown lines, forehead creases and crow’s feet over time. When performed with precision and a light hand, it helps preserve natural movement while slowing the formation of future wrinkles. At Dr Joney De Souza Clinic, the focus is always on subtlety, balance and long term skin health, using advanced techniques to achieve results that look effortless, not obvious. You can get a feel for the types of individual result from these official anti-wrinkle injections before and after photos from anti-wrinkle injections Cosmetic.

Meet Dr Joney
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Your anti-wrinkle injection Treatment Journey at Dr Joney De Souza Clinic

Every treatment at Dr Joney De Souza Clinic begins with a personal consultation. During this appointment, Dr Joney will take time to understand your goals, assess your facial anatomy, and discuss the areas you’d like to improve. He will explain how anti-wrinkle injections work, what results you can expect, and whether any complementary treatments might enhance your outcome.

Once your bespoke plan is agreed, the skin is gently cleansed and, if needed, a topical anaesthetic can be applied to make the process more comfortable. Dr Joney uses fine micro-needles and advanced injection techniques to ensure precision and natural-looking results. The injections themselves take just a few minutes, with minimal discomfort and no downtime.

Aftercare

After treatment, you can return to your normal day straight away. You may notice small marks or slight redness where the injections were placed, which usually disappear within an hour. The effects begin to appear gradually over the next few days, with full results visible within about two weeks.

Dr Joney will advise you on aftercare, such as avoiding strenuous exercise or massaging the area for 24 hours. Many patients choose to book a review appointment around two weeks later, where any fine-tuning can be carried out if necessary. Results typically last between three to six months, depending on your individual response and the area treated. With regular maintenance treatments, you’ll notice smoother skin, softer lines, and a fresher, more relaxed appearance that still looks entirely natural.

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Anti-wrinkle Frequently Asked Questions

anti-wrinkle injections are FDA approved for improving fine lines and wrinkles in areas where over-contracted underlying muscles cause the skin to look stressed and aged.

A treatment with anti-wrinkle injections are non-surgical, quick, and safe. Small amounts of product are finely injected into specific areas to temporarily relax the underlying muscle, softening facial lines and wrinkles.Anti-wrinkle injections work best for glabella (frown lines), lines on the bridge of the nose, crow’s feet, neck bands, and chin dimpling. The treatment is also effective for excessive sweating (hyperhidrosis) and teeth grinding (bruxism).

There is virtually no downtime. Minor redness, swelling, or bruising may occur at the injection site. Results appear within 4–10 days and last between 3–6 months.

Ask us your question

What can anti-wrinkle injections do for me?

Facial lines are caused by repeated use of muscles for expression such as squinting and frowning. By injecting small amounts of wrinkle-relaxing solution into specific muscles, movement is reduced and lines are softened. The treatment helps break the habit of frowning or squinting and prevents new lines from forming. Prevention is often better than cure.

Why should I choose Dr Joney De Souza and his Associates for anti-wrinkle injections?

Dr Joney De Souza and his Associates are highly qualified and experienced. Every anti-wrinkle injection treatment is carried out by either Dr Joney de Souza or his Associates, ensuring expert assessment, careful dosing and a refined approach tailored to your facial anatomy. Patients value his ability to achieve subtle rejuvenation without altering expression or creating an over-treated look.

Who is suitable for anti-wrinkle treatment?

A medical consultation is required to assess suitability. anti-wrinkle injections cannot be performed during pregnancy.

What’s the treatment like?

The procedure is quick and virtually painless, though topical anaesthetic cream may be applied first. The product is injected in small amounts using a fine needle, and any discomfort is brief. Slight redness or swelling resolves within 30 minutes. Lines diminish over a few days and full results appear within two weeks. Effects typically last 3–4 months. Regular treatments every 3–4 months deliver the best long-term results.

What happens afterwards?

There may be mild redness, swelling, or bruising that fades quickly. Results develop gradually over about a week. Top-ups are recommended every 3–6 months as effects fade. Most patients are delighted with their refreshed, natural results.

Is your anti-wrinkle injection treatment carried out in the Marylebone clinic?

Yes. All anti-wrinkle injection treatments are performed at our Marylebone clinic on Blandford Street. Every appointment is carried out by Dr Joney himself to ensure the highest standard of care and consistent, natural looking results.

How do I get to the clinic in Marylebone for my anti-wrinkle injections appointment?

Our clinic is located at 49 Blandford Street, a short walk from Bond Street, Baker Street and Marylebone stations. Patients often find it easy to visit during a lunch break or on their way home from work.

Will my results look natural?

Yes. Dr Joney focuses on precise, subtle treatment to maintain natural facial expression. The aim is a fresher, rested look rather than a frozen appearance.

 4.9 ★★★★★

Read our reviews

Our patients return to us year after year for natural, balanced results. Every review reflects our commitment to precision, safety and a personalised approach to aesthetic care.

I genuinely wouldn’t trust anyone else with my skin. Dr Joney de Souza remains my top recommendation for anyone seeking expert aesthetic care in London. He has a calm, professional manner and always takes the time to truly listen and understand what you’re hoping to achieve. His approach is natural and refined, you always leave looking like the best version of yourself, never overdone. The clinic is a beautiful, welcoming space in the heart of London, and the entire team is warm, knowledgeable, and highly professional. Dr Joney’s expertise and eye for detail are truly exceptional, and the results speak for themselves.
Daniele Bernardinetti
Daniele Bernardinetti
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I’ve known Dr. Joney de Souza for years and can’t recommend him highly enough. He’s a true expert in aesthetics — always professional, innovative, and genuinely caring. His treatments are subtle, natural, and always tailored to your needs. A standout in London’s aesthetic scene!
Osmar Pinheiro Bacelar Junior
Osmar Pinheiro Bacelar Junior
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I had treatment at Dr. Joney De Souza’s clinic one month ago and had a fantastic experience. Dr. De Souza was friendly, highly knowledgeable, and made me feel completely comfortable and at ease throughout the process. His great sense of humor also helped create a relaxed atmosphere. I’m really happy with the results and will definitely be coming back for regular visits. Highly recommend this clinic!
Daluna London
Daluna London
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The clinic is so very welcoming and really listens to how and what you would like to achieve, i have had several facial treatments and it has made such a difference to my confidence. David and everyone in the clinic are professional and experts in what they do, they treat you with a really personal service. My skin has never looked so clear or glowing .. I’ve had people stop and ask me what and where do I have my treatments .. thank you
Jayne Gates
Jayne Gates
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I had an excellent experience with Dr. Joney de Souza and his team. From start to finish, they were incredibly supportive, making me feel at ease throughout the entire process. Dr. Joney has both a sharp eye and a soft hand, striking the perfect balance between precision and gentleness. The team’s expertise speaks for itself, and their approach is as refined as it is reassuring. Highly recommended.

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Profhilo vs Profhilo Structura - what is the difference? 👉

Both are injectable treatments containing hyaluronic acid. Both are produced by the same manufacturer. And both deliver beautiful, natural results. But they are not the same treatment, and understanding the difference is important when it comes to choosing the right one for your skin.

🫧 Profhilo
Profhilo is a skin booster. Its primary purpose is to deeply hydrate the skin, improve overall skin quality and stimulate the production of collagen and elastin. It spreads through the tissue to treat a wide area, leaving the skin looking more radiant, plump and youthful. It is suitable for a broad range of patients and is particularly effective for anyone experiencing dullness, dehydration or a general loss of skin glow.

🫧 Profhilo Structura
Profhilo Structura is specifically designed to address skin laxity and loss of firmness. It contains a higher concentration of high molecular weight hyaluronic acid, which works to remodel the deeper structural layers of the skin, restoring lift, firmness and definition in areas where the skin has begun to lose its architecture over time. It is particularly effective for the cheeks, jawline and neck.

Which one is right for you?
If your primary concern is skin quality, hydration and radiance, Profhilo is likely the right starting point. If you are noticing a loss of firmness, definition or lift, Profhilo Structura may be the more appropriate choice. For many patients, the two work beautifully together as part of a combined treatment plan.

The best way to find out is a thorough consultation with one of our medics 🤍Your guide to radiant summer skin ☀️

Summer is here, and your skin needs a little extra love. Swipe through for everything you need to know to keep your skin glowing all season long 👉

PicoSure targets pigmentation, sun damage and uneven skin tone at a cellular level - giving you a clearer, brighter complexion just in time for summer.

SPF 50, every single day. Non-negotiable. UV rays are present rain or shine, and no treatment or product can undo the damage of unprotected sun exposure. Apply every morning and reapply every two hours outdoors. 

Skin boosters deliver deep hydration from within - improving elasticity, smoothing texture and creating that natural, lit-from-within glow that no topical product can replicate. 

📍Marylebone, London | 020 7043 0748 📱A Wonderful Review for Roma ✨

At Dr. Joney De Souza Skin & Laser Clinic, we believe that exceptional results are achieved through expertise, personalised care, and a genuine commitment to every patient’s journey.

We are delighted to share this wonderful feedback for Roma, whose knowledge, skill, and thoughtful approach continue to make a lasting impact on those she treats.

Roma takes the time to understand each individual’s skin concerns and goals, creating tailored treatment plans that deliver beautiful, confidence-boosting results. Her warm and professional manner ensures every patient feels comfortable, informed, and in the safest of hands throughout their journey.

Roma, thank you for the dedication and care you bring to every appointment. We are incredibly proud to have you as part of the clinic.

And to our lovely client, Victoria, thank you for your kind words and for trusting us with your skin health. We are thrilled that you achieved such great results and look forward to welcoming you back soon 🫶If you read one thing today, please let it be this 🤍

July is UV Safety Awareness Month, and as a skin and laser clinic, there is genuinely nothing we feel more passionately about than protecting the skin you’re in.

UV radiation is the leading cause of skin cancer worldwide. UVA rays silently penetrate deep into the skin every single day - breaking down collagen, causing dark spots, wrinkles and long-term cellular damage - while UVB rays trigger the DNA mutations that lead to skin cancer. And they are both present even on overcast days in the UK.

The reality? Nearly 9 in 10 melanomas are preventable. That statistic is both sobering and empowering because it means the choices you make today genuinely matter.

Swipe through for everything you need to know about why UV protection is non-negotiable, what unprotected exposure is doing to your skin right now, and exactly how to protect yourself this summer and beyond...

SPF 50 every morning. A wide-brimmed hat. Shade between 10am and 4pm. UV-blocking sunglasses. Lightweight cover-up. These aren’t just suggestions, they’re the steps that protect your skin, your health and your future 🖤

#uvsafety #uvsafetyawarenessmonth #melanomaawarenessProduct Spotlight of the Month - July ☀️

Meet your summer non-negotiable: ZO Skin Health Daily Sheer Broad-Spectrum SPF 50.

With July bringing longer days, stronger UV rays and more time spent outdoors, there has never been a more important time to make sure your SPF is doing its job properly - and this one delivers on every level.

Unlike your average sunscreen, Daily Sheer protects against the full spectrum of sun damage - including blue light from your phone and screens, and the deeper rays that most SPFs simply don’t block.

It also delivers 12 hours of antioxidant defence against everyday environmental damage, going far beyond what a standard SPF can offer.

The formula is completely non-greasy, water resistant for up to 40 minutes, and dries down to a sheer finish that sits beautifully under makeup. No white cast. No heavy residue. Just effortless, daily protection.

Awarded the Seal of Recommendation by the Skin Cancer Foundation (USA) - because this isn’t just skincare, it’s skin health 🤍

How can you find us?

Our clinic is located in Marylebone, London, in the heart of one of Central London’s most prestigious and renowned medical districts. Perfectly positioned for convenience and discretion, we are easily accessible from across the capital and beyond.

We welcome patients from Mayfair, Harley Street, Marylebone, Knightsbridge, Belgravia, Chelsea, Kensington, Fitzrovia and St John’s Wood, as well as international patients visiting London for specialist treatment.

Our location benefits from excellent transport connections, with close proximity to major Underground stations, mainline rail links and direct access to Heathrow, Gatwick and London City airports. Several secure parking facilities and convenient chauffeur drop-off points are available nearby, ensuring a seamless and comfortable visit.

Whether you are travelling from elsewhere in London, across the UK or internationally, our clinic offers a calm, private and exclusive setting in one of the world’s leading medical destinations.

Opening hours
Monday
9 am–6 pm
Tuesday
9 am–6 pm
Wednesday
9 am–6 pm
Thursday
9 am–6 pm
Friday
9 am–6 pm
Saturday
Closed
Sunday
Closed
Dr Joney De Souza
49 Blandford St, London W1U 7HH
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