Doctor-led anti-wrinkle injections in Marylebone, London from £190. Soften frown lines, forehead and crow’s feet naturally with our doctors. Book today.
If the lines that appear when you frown, raise your brows or smile have started to linger even after your face relaxes, anti-wrinkle injections at Dr Joney De Souza in Marylebone can soften them while keeping your face expressive and your own. This treatment is a good fit if you recognise any of these concerns.
It is not the right choice for everyone. Volume loss in the cheeks or under the eyes, or deep folds that stay when your face is at rest, respond better to dermal fillers or a skin-quality treatment such as Profhilo. Your practitioner will tell you honestly at consultation if a different approach would serve you better.
Anti-wrinkle injections are a prescription-only medical treatment that gently relaxes the small muscles responsible for expression lines. When those muscles work a little less forcefully, the skin above them stops creasing with every frown and smile, so the lines soften from the surface up. Movement is eased rather than switched off, which is why your expressions stay natural.
The effect builds over a few days and settles at around two weeks, giving a fresher, more rested look that never appears frozen. The approach here is conservative and doctor-led, with the dose planned around your individual facial anatomy rather than a set formula.
Related treatments at Dr Joney De Souza: dermal fillers, an 8-point lift, Profhilo and softening fine lines.
Every result below is a real Dr Joney De Souza patient. Use the slider to see the change. Results vary from person to person.
Expression lines form because a muscle repeatedly folds the skin above it. The treatment temporarily eases the nerve signal that tells that muscle to contract, so when a small, precise dose is placed into a target muscle, the muscle relaxes and the skin is no longer creased each time you frown or smile. Existing lines soften and new ones are slowed. The result is fully temporary, so movement gradually returns as the effect wears off.
A tiny, measured amount of a purified, prescription-only medicine is placed into the specific muscle causing a line. The dose is small and targeted, so only the intended muscle is affected.
Dynamic lines form when a muscle repeatedly folds the skin above it. Once that muscle is relaxed, the skin stops creasing with every expression, so it gradually smooths from the surface.
Your practitioner softens rather than freezes the muscle and doses conservatively, so you keep balanced, natural movement. The aim is a rested look, not a blank one.
Most people notice the effect from three to five days, with the full result settling by around two weeks as the muscles fully relax.
Results typically last three to four months. The body gradually restores the nerve signal, so movement returns and a top-up maintains the effect.
The face is a network of small muscles that balance one another. Precise, anatomy-led placement is what separates a natural result from a heavy or uneven one, which is why every treatment is doctor-led.
From your first consultation to your review, every step at Dr Joney De Souza is doctor-led and unhurried. Here is what to expect.
Your practitioner reviews your concerns, watches how your face moves and checks your medical history, then agrees a precise plan and dose with you. Nothing is rushed, so you know exactly what to expect before anything begins.
The appointment takes about 15 minutes. Using a very fine needle, your practitioner places small, measured doses into the mapped points. Most patients describe only a brief pinch, and no anaesthetic is needed.
You can return to your day straight away. We simply ask you to avoid rubbing the area, strenuous exercise and lying flat for a few hours. The result then develops over the following days, and a review confirms you are happy.
Anti-wrinkle injections look effortless only when they are placed with precision by an experienced doctor. Patients choose our Marylebone clinic because every appointment is medically led, with a focus on subtlety, balance and long-term skin health.
“My ‘less is more’ approach has become the mainstay of my practice and clients appreciate that they will have natural looking results” Dr Joney De Souza, The Sybarite
Anti-wrinkle treatment is priced by the number of areas treated and planned around your goals.
The right dose and number of areas depend on your face, so your exact plan and price are confirmed at your personal consultation.
| Treatment | Associate (£) | With Dr Joney (£) |
|---|---|---|
1 area | 335 | 395 |
2 areas | 360 | 425 |
3 areas | 420 | 495 |
Masseter (jaw slimming) | 460 | 545 |
Excessive sweating (hyperhidrosis) | 510 | 600 |
Neck bands (Nefertiti lift) | 340 | 400 |
Gummy smile | 235 | 275 |
Chin (dimpling) | 235 | 275 |
Bunny lines | 235 | 275 |
Mini brow lift | 255 | 300 |
Smokers' lines | 190 | 225 |
Anti-wrinkle injections relax the muscles that cause dynamic lines, while dermal fillers restore volume and structure lost with age. They do different jobs, so they work beautifully together as part of one balanced plan.
Many patients pair the two so movement lines are softened while areas such as the cheeks, tear troughs or lips are subtly refreshed. Your practitioner will advise whether a combination suits your goals.
Related reading: anti-wrinkle treatments in London.
Below are the questions patients ask most, including how the treatment compares with other options in Marylebone.
Pricing depends on the number of areas treated, so the fairest way to quote is after a quick assessment. Every plan and price is confirmed at your consultation, and each treatment includes the doctor-led assessment and a follow-up review.
Most patients feel only a brief pinch from the very fine needle, and no anaesthetic is needed. There is no real downtime. Mild redness or tiny bumps settle within an hour or two, and you can return to your day straight away.
Results typically last three to four months. With regular treatment, some patients find the effect lasts a little longer over time. A top-up maintains a consistent, natural result.
No. Your practitioner doses conservatively and places the medicine precisely, so you keep natural expression. The goal is to look rested and refreshed, not treated. It will not smooth deep folds that stay when your face is at rest, and it will not add volume, both of which need a different treatment.
They have a long, well-established safety record when administered by an experienced medical practitioner. The treatment is carried out by one of our doctors, Dr Joney De Souza or Dr Mattia Parducci, after reviewing your suitability, which keeps any risk to a minimum.
They do different jobs. Anti-wrinkle injections relax the muscles behind dynamic lines, dermal fillers restore lost volume and structure, and Profhilo improves overall skin quality and hydration. Your practitioner often combines them for a balanced result, and can also advise on softening early fine lines.
Yes. Beyond facial lines, the same medicine can reduce underarm excessive sweating and slim or soften a strong jawline. Your practitioner will confirm whether these advanced uses suit you at your consultation.
You can book by WhatsApp, phone or online. The clinic sits in Marylebone, close to Harley Street and within easy reach of Bond Street, Baker Street and Marble Arch, so it is convenient across central London.
See why patients across London trust Dr Joney De Souza for natural, doctor-led anti-wrinkle injections in Marylebone.
I highly recommend Dr. Joney and his clinic. I have been his patient for many years and he is definitely one of the best. His work is natural and subtle, he always puts the patient’s interest first and will never try to upsell unnecessary treatments.
Had an excellent experience today getting the Profhilo treatment done by Dr. Joney De Souza. The entire team was so friendly, and prepped me about what I should expect during and after the treatment.
Dr Joney is the most wonderful Dr, kind and caring and highly experienced. I feel safe in his care and trust his opinion 100%.
