Injectables in London

Doctor-led injectables at Dr Joney De Souza in Marylebone, London: anti-wrinkle injections, dermal and lip fillers, non-surgical rhinoplasty and more. From £335.

Injectables

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Procedure Time
30-45 mins
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Back to Work
Same day
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Anaesthetic
Topical optional
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Results
From 2-4 weeks
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Sessions
2-3 sessions recommended
Price From
£400
per session (Associate clinician)

Doctor-led injectables, planned to still look like you

Dr Joney De Souza Skin and Laser is a doctor-led clinic in Marylebone, central London, and injectables are at the heart of what we do. Most people who come to us are not asking for a particular product. They want a specific result, whether that is softer frown lines, fuller cheeks, more defined lips, a smoother nose profile or a jawline that looks lifted. The job of a good injector is to match the treatment to the face in front of them, not to sell the same syringe to everyone.

Every injectable at the clinic is delivered or overseen by a doctor, either Dr Joney De Souza or Dr Mattia Parducci. The house style is deliberately restrained, so results are noticed as you looking well rather than as work. Your consultation begins with the concern, then we recommend the treatment, the amount and the plan that suit you.

My ‘less is more’ approach has become the mainstay of my practice, and clients appreciate that they will have natural looking results.

Dr Joney De Souza

Compare our injectable treatments in London

Each injectable does a different job. Some relax the muscles that crease the skin, others restore volume or reshape a feature. Use the table to see what each treatment is best for, then let your consultation confirm the right choice for your face.
Compare injectablesAnti-wrinkle injectionsMuscle relaxingDermal fillersVolume and contourLip fillersLip definitionRhinoplastyNon-surgical nose8-point liftFiller facelift
Anti-wrinkle injectionsDermal fillersLip fillersRhinoplasty8-point lift
Best forAnti-wrinkle injections
Frown lines, forehead lines and crow's feet
Dermal fillers
Volume in cheeks, chin, jawline and tear troughs
Lip fillers
Shape, definition and hydration for the lips
Rhinoplasty
Smoothing a bump or refining the tip of the nose
8-point lift
Overall facial balance and a subtle lift
How it worksAnti-wrinkle injections
Relaxes the muscles that crease the skin
Dermal fillers
Hyaluronic acid gel restores or adds volume
Lip fillers
Hyaluronic acid gel shapes and hydrates the lips
Rhinoplasty
Filler reshapes the nose without surgery
8-point lift
A structured plan of filler across key support points
DowntimeAnti-wrinkle injections
None, avoid rubbing the area for a day
Dermal fillers
Little, mild swelling or bruising possible
Lip fillers
A day or two of swelling settles quickly
Rhinoplasty
Minimal, some tenderness
8-point lift
Minimal, some swelling
ResultsAnti-wrinkle injections
Start 3 to 14 days, last 3 to 4 months
Dermal fillers
Seen straight away, last 6 to 18 months
Lip fillers
Seen straight away, last 6 to 12 months
Rhinoplasty
Seen straight away, last up to a year
8-point lift
Seen straight away, settle over two weeks
Price fromAnti-wrinkle injections
£335
Dermal fillers
£385
Lip fillers
£385
Rhinoplasty
£450
8-point lift
£980
View anti-wrinkleView dermal fillersView lip fillersView nose reshapingView 8-point lift
Anti-wrinkle injectionsMuscle relaxing
Anti-wrinkle injections
Best for
Frown lines, forehead lines and crow's feet
How it works
Relaxes the muscles that crease the skin
Downtime
None, avoid rubbing the area for a day
Results
Start 3 to 14 days, last 3 to 4 months
Price from
£335
View anti-wrinkle
Dermal fillersVolume and contour
Dermal fillers
Best for
Volume in cheeks, chin, jawline and tear troughs
How it works
Hyaluronic acid gel restores or adds volume
Downtime
Little, mild swelling or bruising possible
Results
Seen straight away, last 6 to 18 months
Price from
£385
View dermal fillers
Lip fillersLip definition
Lip fillers
Best for
Shape, definition and hydration for the lips
How it works
Hyaluronic acid gel shapes and hydrates the lips
Downtime
A day or two of swelling settles quickly
Results
Seen straight away, last 6 to 12 months
Price from
£385
View lip fillers
RhinoplastyNon-surgical nose
Rhinoplasty
Best for
Smoothing a bump or refining the tip of the nose
How it works
Filler reshapes the nose without surgery
Downtime
Minimal, some tenderness
Results
Seen straight away, last up to a year
Price from
£450
View nose reshaping
8-point liftFiller facelift
8-point lift
Best for
Overall facial balance and a subtle lift
How it works
A structured plan of filler across key support points
Downtime
Minimal, some swelling
Results
Seen straight away, settle over two weeks
Price from
£980
View 8-point lift

Why patients choose Dr Joney De Souza for injectables

An injectable is only as good as the hand and the eye behind it. Safety and a natural result come down to a medical understanding of the face and the judgement to know when less is more.

  • Doctor delivered. Your treatment is performed or overseen by Dr Joney De Souza or Dr Mattia Parducci, both experienced medical injectors.
  • Natural by default. The clinic is known for restraint. Results are meant to refresh, not to change your features, and you can always build up gradually.
  • Honest advice. If an injectable is not the right answer for your concern, we will say so rather than sell you a treatment that will disappoint.
  • A trusted central London clinic. Our Marylebone practice welcomes patients from across London, and Dr Joney De Souza’s work has featured in the national and beauty press.
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What to expect, step by step

Knowing what happens at each stage takes the nerves out of injectable treatment. From your first assessment to your review, every step is planned around your face. Open the stages below to see how it works.

Consultation

Your visit starts with the concern, not the syringe. We assess your face, talk through your goals and your history, and recommend the treatment, the amount and the plan that suit you.

Your plan

We agree a clear plan and price before anything begins, including whether a single treatment or a staged approach will serve you best.

Treatment

Your injectable is carried out by Dr Joney De Souza or Dr Mattia Parducci. Fine needles are used, filler contains anaesthetic, and numbing cream is available for sensitive areas such as the lips.

Aftercare

We give you clear, simple aftercare so any swelling or bruising settles well and your result develops as it should.

Review

You return for a review so we can check your result and plan any refinement or maintenance. Your outcome is guided rather than left to chance.

Not sure which injectable is right for you?

Book a consultation in Marylebone and a doctor will match the treatment, the amount and the plan to your face. There is never any pressure to proceed.

Book a consultation

Injectables in London: your questions answered

Below are the questions we hear most about injectable treatment at our Marylebone clinic. If yours is not covered, just ask at your consultation.

How much do injectables cost in London?

It depends on the treatment and the amount used. As a guide, anti-wrinkle injections start from £335, dermal and lip fillers from £385, non-surgical rhinoplasty from £450, and an 8-point lift from £980. Every price includes a doctor-led assessment. You can see the full breakdown on our prices page, and we confirm your plan at consultation.

Will I still look like myself?

Yes. The clinic’s approach is deliberately conservative, especially for a first treatment. The goal is to soften or restore, not to change your features, and results can always be built up gradually.

Why do you say anti-wrinkle injections rather than the brand name?

Prescription-only medicines cannot be advertised by brand name in the UK, so we use the clinical term. We will discuss the specific product with you during your consultation.

Do injectables hurt?

Most people find them very tolerable. Fine needles are used, fillers contain anaesthetic, and numbing cream is available for more sensitive areas such as the lips. Any tenderness afterwards settles quickly.

What is the difference between anti-wrinkle injections and fillers?

Anti-wrinkle injections relax the muscles that create expression lines, while dermal fillers restore or add volume. Many people combine the two, and your consultation will confirm the right mix.

How long do results last?

Anti-wrinkle results typically last three to four months. Fillers last from six to eighteen months depending on the product and area treated. Your doctor will guide you on maintenance.

Can fillers be dissolved if I change my mind?

Hyaluronic acid fillers can be dissolved if needed, which is one reason they are so widely used. We will always talk through the options honestly before you proceed.

Who carries out the treatment?

Every injectable is performed or overseen by Dr Joney De Souza or Dr Mattia Parducci within a doctor-led clinic in Marylebone, close to Bond Street, Baker Street and Marble Arch.

4.9 ★★★★★

Read our reviews

Year after year, patients return to Dr Joney De Souza for careful, doctor-led results. Every review reflects a commitment to precision, safety and a personalised approach at our Marylebone clinic.

I highly recommend Dr. Joney and his clinic. I have been his patient for many years and he is definitely one of the best. His work is natural and subtle, he always puts the patient’s interest first and will never try to upsell unnecessary treatments.

Had an excellent experience today getting the Profhilo treatment done by Dr. Joney De Souza. The entire team was so friendly, and prepped me about what I should expect during and after the treatment.

Dr Joney is the most wonderful Dr, kind and caring and highly experienced. I feel safe in his care and trust his opinion 100%.

Shelley Maxwell
Shelley Maxwell
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The SPF market can feel overwhelming, and we completely understand why 👇

Too many options, too many textures, too many excuses. So let us make it simple.

We hear the same things all the time. It breaks me out. It leaves a white cast. It feels greasy. I just cannot be bothered. And honestly? Every single one of those concerns is valid. But in 2026, none of them are reasons not to wear SPF anymore.

The ZO Skin Health SPF range, which we stock here at Dr Joney De Souza Skin & Laser, has an option for every single skin type, concern and lifestyle. And we mean that.

💭Oily or acne-prone skin? The Sheer Fluid SPF 50 is lightweight, oil-free and non-comedogenic. No breakouts. No shine.

💭Want your SPF to double as a primer? The Sunscreen + Primer SPF 30 creates a flawless base for makeup in one step.

💭Need something for active days or the beach? The Daily Sheer SPF 50 is water resistant and suitable for all skin tones with zero white cast.

💭Want a little coverage too? The Smart Tone SPF 50 adapts to your skin tone for a subtle, skin-perfecting finish.

And for anyone who just cannot be bothered with reapplying? The Sunscreen + Powder SPF 30 is a brush-on powder that goes straight over your makeup, tops up your protection and controls shine at the same time. No fuss. No excuses.

There is an SPF for everyone. Come and find yours today 🤍Profhilo vs Profhilo Structura - what is the difference? 👉

Both are injectable treatments containing hyaluronic acid. Both are produced by the same manufacturer. And both deliver beautiful, natural results. But they are not the same treatment, and understanding the difference is important when it comes to choosing the right one for your skin.

🫧 Profhilo
Profhilo is a skin booster. Its primary purpose is to deeply hydrate the skin, improve overall skin quality and stimulate the production of collagen and elastin. It spreads through the tissue to treat a wide area, leaving the skin looking more radiant, plump and youthful. It is suitable for a broad range of patients and is particularly effective for anyone experiencing dullness, dehydration or a general loss of skin glow.

🫧 Profhilo Structura
Profhilo Structura is specifically designed to address skin laxity and loss of firmness. It contains a higher concentration of high molecular weight hyaluronic acid, which works to remodel the deeper structural layers of the skin, restoring lift, firmness and definition in areas where the skin has begun to lose its architecture over time. It is particularly effective for the cheeks, jawline and neck.

Which one is right for you?
If your primary concern is skin quality, hydration and radiance, Profhilo is likely the right starting point. If you are noticing a loss of firmness, definition or lift, Profhilo Structura may be the more appropriate choice. For many patients, the two work beautifully together as part of a combined treatment plan.

The best way to find out is a thorough consultation with one of our medics 🤍Your guide to radiant summer skin ☀️

Summer is here, and your skin needs a little extra love. Swipe through for everything you need to know to keep your skin glowing all season long 👉

PicoSure targets pigmentation, sun damage and uneven skin tone at a cellular level - giving you a clearer, brighter complexion just in time for summer.

SPF 50, every single day. Non-negotiable. UV rays are present rain or shine, and no treatment or product can undo the damage of unprotected sun exposure. Apply every morning and reapply every two hours outdoors. 

Skin boosters deliver deep hydration from within - improving elasticity, smoothing texture and creating that natural, lit-from-within glow that no topical product can replicate. 

📍Marylebone, London | 020 7043 0748 📱A Wonderful Review for Roma ✨

At Dr. Joney De Souza Skin & Laser Clinic, we believe that exceptional results are achieved through expertise, personalised care, and a genuine commitment to every patient’s journey.

We are delighted to share this wonderful feedback for Roma, whose knowledge, skill, and thoughtful approach continue to make a lasting impact on those she treats.

Roma takes the time to understand each individual’s skin concerns and goals, creating tailored treatment plans that deliver beautiful, confidence-boosting results. Her warm and professional manner ensures every patient feels comfortable, informed, and in the safest of hands throughout their journey.

Roma, thank you for the dedication and care you bring to every appointment. We are incredibly proud to have you as part of the clinic.

And to our lovely client, Victoria, thank you for your kind words and for trusting us with your skin health. We are thrilled that you achieved such great results and look forward to welcoming you back soon 🫶

How can you find us?

Our clinic is located in Marylebone, London, in the heart of one of Central London’s most prestigious and renowned medical districts. Perfectly positioned for convenience and discretion, we are easily accessible from across the capital and beyond.

We welcome patients from Mayfair, Harley Street, Marylebone, Knightsbridge, Belgravia, Chelsea, Kensington, Fitzrovia and St John’s Wood, as well as international patients visiting London for specialist treatment.

Our location benefits from excellent transport connections, with close proximity to major Underground stations, mainline rail links and direct access to Heathrow, Gatwick and London City airports. Several secure parking facilities and convenient chauffeur drop-off points are available nearby, ensuring a seamless and comfortable visit.

Whether you are travelling from elsewhere in London, across the UK or internationally, our clinic offers a calm, private and exclusive setting in one of the world’s leading medical destinations.

Opening hours
Monday
9 am–6 pm
Tuesday
9 am–6 pm
Wednesday
9 am–6 pm
Thursday
9 am–6 pm
Friday
9 am–6 pm
Saturday
Closed
Sunday
Closed
Dr Joney De Souza
49 Blandford St, London W1U 7HH
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