
Doctor-led treatment for excessive sweating (hyperhidrosis) in Marylebone, London. Prescription-only injections that calm underarm, hand and foot sweating. From £510.
When sweating feels beyond your control and starts dictating what you wear, where you sit and how you shake hands, it is worth doing something about it. Excessive sweating treatment at Dr Joney De Souza Clinic in Marylebone suits anyone whose underarm, palm, sole or forehead sweating persists well past the point of exercise or heat. It helps if you deal with visible sweat marks, damp handshakes or odour worries, and it gives you a non-surgical way to take back control. If everyday antiperspirants have stopped making a difference, this treatment is well worth considering. It will not change how the rest of your body cools itself, and it is not aimed at ordinary sweating in the heat, so your consultation confirms whether it is the right fit for you.
Related treatments at Dr Joney De Souza: Sweatox.

This is a prescription-only medical treatment that calms the chemical signals switching on your overactive sweat glands. Your practitioner places a series of tiny injections just beneath the skin across the affected area, and those signals quieten, so sweating in that spot reduces significantly. The rest of your body carries on regulating temperature exactly as it should, because only the treated glands are affected. The appointment is quick and comfortable and needs no recovery time, so most patients head straight back to their day.
Key benefits:
Your treatment begins with a consultation at Dr Joney De Souza Clinic in Marylebone. Your practitioner assesses how much the sweating affects you, confirms the area to treat and checks that the treatment is suitable. You will hear exactly what to expect and have your questions answered. In most cases no special preparation is needed. You leave with a clear, personalised plan.
On the day, your practitioner cleanses the area and maps out the precise points for treatment, such as across the underarms. For more sensitive areas like the palms or soles, a numbing cream can be applied first. The preparation takes only a few minutes. You simply relax while the area is made ready.
Your practitioner then places a series of very fine injections just beneath the skin across the treatment area. The injections are quick and most patients find them very manageable. The whole appointment usually takes fifteen to thirty minutes. You can return to your day straight afterwards.
The injections quieten the nerve signals that switch on the overactive sweat glands in the treated area. As those signals calm, sweating in that spot reduces significantly. Only the treated glands are affected, so the rest of your body regulates temperature as normal. The effect builds over the following days.
Downtime is minimal, so you can return to normal activities straight away. Mild redness, small bumps or slight tenderness at the injection points usually settle within a few hours to a couple of days. Your practitioner gives you simple aftercare guidance before you leave. Treatment fits comfortably around your schedule.
Most patients notice a clear reduction in sweating within a few days, with the full effect usually settling around ten to fourteen days after treatment. Results typically last four to nine months, so many people repeat treatment once or twice a year. Your practitioner recommends a maintenance schedule that suits you, with realistic expectations set at your consultation.
From your first consultation through to your results, here is what to expect at our Marylebone clinic.
Your journey begins with a consultation at Dr Joney De Souza Clinic in Marylebone. Your consultation is with Dr Joney De Souza or Dr Mattia Parducci, who assesses your concern, confirms the treatment is right for you and plans the area to treat. You will hear what to expect and have your questions answered. In most cases no special preparation is needed. You leave with a clear, personalised plan.
On the day, the area is prepared and your treatment is carried out by one of our doctors, Dr Joney De Souza or Dr Mattia Parducci. It typically takes fifteen to thirty minutes and most patients find it comfortable and straightforward. Your practitioner works methodically across the area for an even result. You can return to your day straight afterwards.
Afterwards, any mild redness or tenderness settles quickly, with little to no downtime. The effect builds over four to fourteen days as the treated glands respond, so the change feels gradual rather than sudden. Your practitioner gives you full aftercare guidance before you leave and advises on maintenance to sustain your result.
Excessive sweating treatment is offered in plenty of places, but here a doctor leads every appointment. Carried out by one of our doctors, Dr Joney De Souza or Dr Mattia Parducci, your treatment starts with a proper assessment of your concern, confirmation of suitability and an injection pattern tailored to your anatomy for an even, effective result. You get honest guidance on realistic outcomes and a clear plan for maintenance, not a rushed procedure. Dr De Souza is known for a restrained, natural approach across all his work.
“My ‘less is more’ approach has become the mainstay of my practice and clients appreciate that they will have natural looking results” Dr Joney De Souza, The Sybarite
That same medical standard is what separates a quick jab from a genuinely well-managed treatment.
Pricing reflects the area treated and the practitioner, and every treatment includes a doctor-led assessment and aftercare. Underarm treatment is the most commonly requested, with other areas such as the palms, soles and forehead confirmed at consultation. Severity varies from person to person, so your plan and cost are agreed with you before treatment begins.
Underarm treatment shown; other areas confirmed at consultation.
| Area | Associate (£) | Dr Joney (£) |
|---|---|---|
Underarms (per session) | 510 | 600 |
The same prescription-only injections that calm excessive sweating are also used to soften facial lines such as frown lines, forehead lines and crow’s feet. Plenty of patients fold the two into a single plan. If you would like to address both, your practitioner can discuss a combined approach at your consultation. You can read more about anti-wrinkle injections before you visit.

Excessive sweating, also known as hyperhidrosis, shapes confidence, clothing choices and daily comfort, and it goes well beyond simply sweating in the heat. The answers below cover what patients most often ask about treating it.

Our patients return to us year after year for natural, precise results. Every review reflects our commitment to clinical excellence, patient safety and a personalised approach to aesthetic care.
Had my second session of PRP with micro needling today and I am so far very happy with my results. Dr De Souza is just the kindest man who really has the best intentions for you.
I highly recommend Dr. Joney and his clinic. I have been his patient for many years and he is definitely one of the best. His work is natural and subtle, he always puts the patient’s interest first and will never try to upsell unnecessary treatments.
Dr Joney is the most wonderful Dr, kind and caring and highly experienced. I feel safe in his care and trust his opinion 100%.