Doctor-led hair loss and restoration treatment in Marylebone, London. Dr Joney De Souza assesses the cause of your thinning first, then matches you to PRP, PRF, polynucleotides or HydraFacial Keravive over a considered course.
Noticing more hair in the brush, a widening parting or a hairline that has quietly crept back is unsettling. The reassuring news is that a great deal can be done to help. At our doctor-led clinic in Marylebone, London, we treat thinning and shedding hair calmly and methodically, starting by understanding your scalp rather than reaching for a fixed package. Hair loss rarely comes from a single cause. It can follow genetics, stress or a shift in hormones, and diet, iron levels or an underlying medical condition may all play a part. Because the right response depends on which of those is driving it, we assess the cause first. Then we match you to the treatment most likely to help.
Several of our treatments draw on your own biology, which is part of what makes them so well suited to long-term scalp and hair health. PRP and PRF are especially popular for the scalp. Both use a small sample of your own blood to support tiring follicles. Over a course, they can improve density and thickness. Polynucleotides (Plinest Hair) work alongside them to calm and condition the scalp. HydraFacial Keravive deep-cleans and nourishes it, so the other treatments work on healthier ground. At your consultation, Dr Joney De Souza studies the pattern and stage of your hair loss. He then explains, in plain terms, which option or combination suits your goal.
If a medical cause is likely, we will say so, and guide you toward the right diagnosis before treatment begins. Results build gradually and are kept up with occasional maintenance. So we set honest expectations from the very first visit. The comparison below is a starting point, not a prescription. Your real answer comes from a face-to-face assessment. Some patients arrive certain they need one specific treatment. Part of our job is to check whether that is genuinely the best route, or whether a different option would serve them better over the course.
| Compare our hair treatments | PRP for HairPlatelet-rich plasma | PRF for HairPlatelet-rich fibrin | PolynucleotidesPlinest Hair | HydraFacial KeraviveScalp health |
|---|---|---|---|---|
 |  | |||
| Best for | PRP for Hair Early to moderate thinning | PRF for Hair Sensitive scalps, slower release | Polynucleotides Weak, dull scalp needing conditioning | HydraFacial Keravive Congested scalp, healthier foundation |
| What it does | PRP for Hair Strengthens tiring follicles | PRF for Hair Sustained support for follicles | Polynucleotides Improves the scalp environment | HydraFacial Keravive Cleanses and nourishes the scalp |
| How it works | PRP for Hair Your own platelets, injected | PRF for Hair Your own fibrin, injected | Polynucleotides Regenerative molecules, injected | HydraFacial Keravive Deep-cleansing scalp treatment |
| Sessions | PRP for Hair Course of 3 | PRF for Hair Course of 2 to 3 | Polynucleotides Course of 2 to 3 | HydraFacial Keravive Course of 3, monthly |
| Downtime | PRP for Hair Same day to 48 hours | PRF for Hair Around 48 hours | Polynucleotides 24 to 48 hours | HydraFacial Keravive None |
| Price from | PRP for Hair £490 | PRF for Hair £490 | Polynucleotides £410 | HydraFacial Keravive £360 |
| View PRP for hair | View PRF | View Plinest Hair | View Keravive |
Hair loss is personal, and the pathway to helping it should feel just as considered. At Dr Joney De Souza Clinic in Marylebone, every hair plan begins with a proper assessment, and stays under medical oversight from start to finish. That matters more with hair than with almost any other concern. The same visible thinning can have very different underlying causes, and a mismatched treatment simply wastes your time and money.
Dr Joney De Souza puts it plainly. “My first job is to find out why your hair is thinning. It is not to reach for a treatment. Get the cause right, set realistic timelines, and patients are far happier with the result.”
Whichever treatment you choose, the pathway follows the same careful stages, running from your first consultation through to your review. Because results build gradually, we set clear expectations at every step, so you always know what comes next.
It begins with a face-to-face consultation in Marylebone, where Dr Joney De Souza reviews your medical history, examines your scalp and talks through your goals. He looks closely at the pattern and stage of your hair loss. His questions cover recent changes to your health, medication, diet and stress. Where it is sensible, he will consider a blood test or referral before any treatment. From there we agree an assessment of the likely cause. Then comes a plan that names the treatment, the areas and the number of sessions, with a confirmed price before anything begins.
Your treatment course is delivered over several visits, spaced to suit the protocol you have chosen. For PRP and PRF, a small blood sample is taken and prepared on the day, and numbing is applied before the injections for comfort. HydraFacial Keravive sessions are gentle and cleansing. You leave with a take-home scalp spray to use between visits. Once the initial course is complete, we review your progress together and plan any maintenance. Hair results are kept up with occasional top-up sessions, rather than a single visit. Photographs at each stage help us judge honestly whether the plan is working for you.
First, Dr De Souza reviews your skin or scalp condition, medical history and goals to confirm suitability and recommend whether PRP, PRF or a combination is right for you. In most cases, he also advises on the number of sessions your concern is likely to need.
Next, you will be asked to avoid blood-thinning medication, supplements and alcohol in the days before your appointment where medically appropriate. Staying well hydrated helps ensure a good quality blood draw on the day.
Using a small sample of your own blood, the team draws, centrifuges and prepares your plasma or fibrin, then applies a topical numbing cream before Dr De Souza injects the treated area. Indeed, most patients describe the sensation as mild pressure rather than sharp pain.
Afterwards, growth factors activate collagen-producing cells over the following weeks, gradually improving skin firmness, texture and radiance or reactivating hair follicles. In general, the full benefit of a course becomes visible around the three-month mark.
Once your session is complete, you will avoid strenuous exercise, saunas and direct sun exposure for a short period while the skin or scalp settles. Dr De Souza then reviews your progress and confirms any maintenance you may need.
The quickest way to a straight answer is a consultation. Book a face-to-face assessment in Marylebone with Dr Joney De Souza, who will examine your scalp and talk through the likely cause of your hair loss. His recommendation covers the treatment or combination most likely to help, with clear pricing and honest timelines. Message the team on WhatsApp and we will arrange a time that suits you.
Below are the questions patients ask most often before starting hair treatment at Dr Joney De Souza Clinic.
At Dr Joney De Souza Clinic in Marylebone, the cost depends on the treatment you choose and the number of sessions you have. HydraFacial Keravive starts from £360 for a single full-scalp treatment. Polynucleotides (Plinest Hair) start from £410. Both PRP for hair and PRF start from £490. Because hair restoration works best as a course, Dr Joney De Souza confirms an itemised price before anything begins. Hair Restore 360, our combination programme, is priced individually at consultation.
It depends on the cause and stage of your hair loss, which is exactly why we take the time to assess you in person first. As a general guide, PRP and PRF suit early to moderate thinning and shedding. Polynucleotides help condition a weak or dull scalp. HydraFacial Keravive resets a congested scalp, so other treatments work on healthier ground. Many patients combine two of these over a course. Dr Joney De Souza recommends the right option after examining your scalp.
Both use a small sample of your own blood, but they are prepared differently. PRP concentrates the growth factors in your platelets and injects them into the scalp to support tiring follicles. PRF is spun more slowly and without anticoagulant. It keeps a natural fibrin matrix and releases its growth factors more gradually. That can suit sensitive scalps and patients who prefer a slower, sustained approach. Dr Joney De Souza advises which is the better fit for your scalp.
Polynucleotides (Plinest Hair) are regenerative molecules. These molecules aim to calm and condition the scalp and support the environment around the follicles. They are often used alongside PRP or PRF rather than on their own, as part of a course. Results build gradually and vary from person to person. We set honest expectations at consultation and review your progress as you go.
HydraFacial Keravive is a non-injectable scalp treatment. It deep-cleanses, exfoliates and nourishes the scalp, then finishes with a take-home scalp spray. This treatment does not replace injectable options. Instead, it improves the condition of the scalp, so PRP, PRF or polynucleotides can work on a healthier foundation. It is delivered by our trained practitioners under medical oversight and involves no downtime.
Most patients find them very manageable, and comfort is something we plan for rather than leave to chance. For the injectable treatments we apply numbing where needed. The initial blood draw for PRP and PRF feels much like a routine blood test, and HydraFacial Keravive is comfortable and non-invasive. You may feel mild pressure or tenderness during the injections, but sharp pain is unusual.
Downtime is minimal, so hair treatment fits easily around a normal week. HydraFacial Keravive has essentially none, so you can return to your day straight away. After the injectable treatments you may notice mild redness or tenderness at the treated sites for a day or so. Most patients are back to normal activities the same day to 48 hours later, and Dr Joney De Souza gives you simple aftercare to follow at home.
It depends on the treatment and your scalp. As a general guide, PRP for hair is usually a course of three. PRF and polynucleotides run to a course of two to three. HydraFacial Keravive is a course of three spaced monthly. Hair results build over a course and are kept up with occasional maintenance rather than a single visit. Dr Joney De Souza confirms your plan after assessing you.
The injectable treatments are PRP, PRF and polynucleotides (Plinest Hair). Dr Joney De Souza plans and performs them himself, using CE-certified preparation for the platelet treatments. He is a medically qualified doctor. HydraFacial Keravive is delivered by our trained practitioners under his oversight. PRP and PRF are considered among the safer options in aesthetic medicine. They use your own blood, with no synthetic material. Even so, every treatment follows a medical assessment first, because suitability varies.
Yes to both. Many of our hair patients are men noticing a receding hairline or thinning at the crown. We also treat women with diffuse thinning or a widening parting. The Marylebone clinic is within easy reach of Bond Street, Baker Street and Marble Arch. Patients travel in from across London and beyond for their treatment course. Because a course involves several visits, many plan their appointments around one trip into central London at a time.
Patients return to Dr Joney De Souza year after year for doctor-led, natural results. Dr Joney De Souza Clinic holds a 4.9-star rating from over 270 verified Google reviews, including PRP and hair loss treatments in London.
I came for PRP hair loss treatment and so far really pleased with the results, have a few more sessions to go. Great clinic and lovely team.
I recently had a HydraFacial with Roma and the results have been nothing short of amazing. Roma was professional and knowledgeable. She took the time to understand my skincare concerns and explained the treatment thoroughly.
Dr Joney is the most wonderful Dr, kind and caring and highly experienced. I feel safe in his care and trust his opinion 100%.
