
Hair Restore 360 is our doctor-led combination for early hair thinning in London, pairing a HydraFacial Keravive scalp cleanse with PRP and polynucleotide injections to help reduce shedding and support denser, healthier hair over a course.
Hair Restore 360 at Dr Joney De Souza Clinic is designed for men and women who are noticing early hair thinning and want to act while their follicles are still active and responsive. Perhaps your parting looks a little wider than it did a year ago, your ponytail feels finer in your hand, or you are simply seeing more strands than usual in the shower. This is exactly the stage at which a combined, regenerative approach tends to help most, and it is a genuinely positive moment to take charge of your hair’s long-term health rather than sit and worry.
There is an honest limit to what any regenerative treatment can achieve, and we would far rather say so at the very start than promise more than we can deliver. Hair Restore 360 is not a substitute for a hair transplant, so where baldness is advanced or complete and very few follicles remain, surgery is likely to serve you better. Dr Joney De Souza will tell you that plainly rather than sell a course that cannot help you. Some hair loss also has a medical cause, from thyroid changes to iron deficiency, so we assess carefully first and, where needed, ask you to see your GP for blood tests before we begin.

Hair Restore 360 is the clinic’s most comprehensive regenerative hair treatment, bringing three complementary therapies together in a single, carefully sequenced appointment. The session opens with a HydraFacial Keravive scalp cleanse that clears, exfoliates and nourishes the scalp to prepare a healthy environment for growth. Next comes platelet-rich plasma (PRP), drawn and concentrated from your own blood so that your own growth factors can be delivered directly to weakened follicles. Polynucleotides, a purified regenerative gel, then help repair the scalp tissue and improve the environment in which hair grows.
Used together, these three steps do something that no single treatment quite matches on its own. The scalp is cleansed and prepared, the follicles are stimulated, and the surrounding tissue is supported, all within one coordinated plan. Our aim is gentle and realistic, because we want to reduce shedding, improve density and thickness, and support healthier, stronger hair steadily over a course. It suits both men and women in the earlier stages of thinning.
Hair Restore 360 also sits within our wider, longevity-minded approach to scalp and hair health, where the scalp is treated as living skin worth caring for over the years ahead. Rather than chasing one dramatic moment, we focus on steadily investing in the condition of your scalp so that healthy growth has the best possible foundation for the future.

Each of the three therapies targets a different part of the same underlying problem, which is precisely why combining them works so well in one visit. The Keravive step uses a gentle vortex system to lift away dead skin, excess oil and product build-up before flooding the follicles with a nourishing growth-factor serum. A clean, well-conditioned scalp then absorbs everything that follows far more effectively.
PRP does the stimulating, and we concentrate the platelets in a small sample of your blood before placing that plasma carefully into the thinning areas. Its growth factors signal to resting follicles and coax them back toward an active growth phase while improving circulation around each root. Polynucleotides then do the repairing, because this purified gel calms the scalp and helps rebuild the surrounding tissue so the follicles sit in healthier ground.
Every appointment opens with a close look at your scalp and pattern of thinning. One of our trained practitioners then carries out the HydraFacial Keravive cleanse. A vortex handpiece exfoliates the scalp, clears congestion around the follicles and infuses a nourishing serum. This step takes around 20 minutes and leaves the scalp primed for the injectable stages.
Dr Joney De Souza draws a small sample of blood from your arm. The volume is similar to a routine blood test. The sample spins in a centrifuge for about 10 minutes, which separates and concentrates the platelet-rich plasma ready for use. Most patients feel only the brief pinch of the draw itself.
A topical numbing cream is applied across the treatment area and left to take effect. This makes the injection stages very comfortable. Most people describe the sensation that follows as light pressure rather than pain. We never rush this part.
Dr Joney De Souza places the PRP into the thinning zones with a fine needle, in an even grid. He then follows with the polynucleotide injections to support the scalp tissue. Performing both in one visit is what makes this a true combination. The stage usually takes 30 to 40 minutes, depending on the size of the area.
A brief scalp massage settles everything into place, and you leave with a take-home Keravive scalp spray and written aftercare. Mild redness or tenderness is normal for a day or two. A little extra shedding in the first few weeks is expected as follicles reset. Results build gradually, with most patients reviewing progress after their three monthly sessions.
No two scalps thin in quite the same way, so every Hair Restore 360 plan begins with a face-to-face assessment in Marylebone before any treatment is booked. From there, most patients follow a course of three sessions spaced roughly a month apart, with a review afterwards to help decide on gentle maintenance. Here is what to expect at each stage of the journey.
As advised at your consultation, avoid blood-thinning supplements for a week beforehand, where it is medically safe. That includes fish oil, high-dose vitamin E and aspirin. Arrive with clean, product-free hair. A good night’s sleep and a normal meal make the blood draw easier. If anything about your health has changed since your assessment, tell us on arrival.
A full session runs 75 to 90 minutes from start to finish. It moves through the Keravive scalp cleanse, the blood draw and PRP preparation, and topical numbing. Dr Joney De Souza then performs the PRP and polynucleotide injections. The team checks your comfort throughout and can pause at any point. Most patients find the numbing makes the injections easy to tolerate.
Leave the scalp to settle and avoid washing your hair for 24 hours. Then skip vigorous exercise, swimming and direct sun for 48 hours. Mild redness or tenderness usually fades within a day or two. A little extra shedding in the first few weeks is normal and not a cause for worry. Resting hairs make way for new growth. Use your take-home scalp spray as directed to extend the benefit between sessions.
Dr Joney De Souza is an experienced aesthetic physician based in Marylebone, in the heart of Central London, and Hair Restore 360 is very much a doctor-led combination. The PRP and polynucleotide injections are performed by Dr Joney De Souza himself, while the HydraFacial Keravive scalp cleanse is delivered by the clinic’s trained practitioners under his medical oversight. Our clinic holds a 4.9 rating from more than 270 verified Google reviews, and careful assessment is the thread that runs through everything we do.
Managing expectations matters to us as much as the treatment itself, because Hair Restore 360 works best for early to moderate thinning. Results build steadily over a course rather than overnight, and gentle ongoing maintenance is what protects and extends those gains over time. If your hair loss is advanced, or if we suspect a medical cause behind it, we will say so honestly and then point you toward the right option, whether that is a hair transplant or a check with your GP.
“I never start with a needle. I start by looking at the scalp, the pattern of the thinning and your history, and only then do I decide whether one therapy or a combination gives you the best chance of a genuine improvement. If I do not think it will help you, I will say so.” Dr Joney De Souza
Hair Restore 360 is priced on consultation rather than as a fixed package, because it is a genuinely bespoke combination and the three therapies are costed individually. Your plan is shaped around how much thinning you have, the size of the area treated and how your scalp responds over time. Most patients begin with a course of three sessions spaced monthly, then move to occasional maintenance that supports the long-term health of the scalp. Your exact costs are confirmed in writing at your assessment, with no obligation to proceed.
Everything a single Hair Restore 360 session covers, and what each step does for your scalp.
| Treatment | 1 session (£) | 3 session (£) |
|---|---|---|
Hair Restore | 1300 | 3600 |
Hair Restore 360 is one route among several, and the right starting point really depends on your scalp and your goals. Our Hair Health hub sets out every hair treatment we offer side by side, from PRP to scalp-focused care, so you can compare them calmly before your assessment. If you are still weighing things up, that is a good place to begin.

Common questions we hear about Hair Restore 360 at our Marylebone clinic. If yours is not covered here, ask us at your assessment or over WhatsApp.
Hair Restore 360 is our most comprehensive regenerative hair treatment. It combines three therapies in one appointment: a HydraFacial Keravive scalp cleanse and platelet-rich plasma (PRP) from your own blood. It also uses polynucleotides to support the scalp tissue. The goal is to reduce shedding and support denser, healthier hair over a course.
Most patients start with a course of three sessions, spaced about a month apart. We then review your progress and plan any maintenance. The exact number depends on how much thinning you have and how your scalp responds. This is why we assess first.
Regenerative hair treatment works gradually. Early changes in scalp condition can show within a few weeks. Improvements in density and thickness tend to build over three to six months as follicles move through new growth cycles. Results vary from person to person.
Most patients find it very manageable. The Keravive cleanse is relaxing, and a topical numbing cream is applied before the injections. The PRP and polynucleotide stages usually feel like light pressure rather than pain. Tell us at any point if you need a break.
Hair Restore 360 is priced on consultation, because it is a bespoke combination costed individually rather than a fixed package. As a guide, the component treatments start from £360 for a Keravive scalp cleanse. Polynucleotides start from £410 and PRP from £490. Your exact plan is confirmed in writing at your assessment.
There is little downtime for most people. You may have mild redness or tenderness for a day or two. We ask you to avoid washing your hair for 24 hours. Also skip strenuous exercise, swimming and direct sun for 48 hours. Most patients return to work the same day.
It is a doctor-led combination. Dr Joney De Souza performs the PRP and polynucleotide injections. One of our trained practitioners delivers the HydraFacial Keravive scalp cleanse under medical oversight. The plan itself is set by the doctor after your assessment.
Yes. Hair Restore 360 suits both men and women in the earlier stages of thinning, including pattern thinning and diffuse shedding. Post-partum shedding can also respond well once cleared with your GP. We confirm suitability at your face-to-face assessment.
A little extra shedding in the first few weeks is normal and expected. As follicles reset and enter a new growth phase, some resting hairs are released. This makes way for stronger new growth. This settles as the course progresses, and it is not a sign the treatment is failing.
Results do not last forever, because hair thinning is an ongoing process. Most patients maintain their improvement with occasional top-up sessions after the initial course, typically every few months. Your scalp assessment guides how often maintenance is worthwhile for you.
The treatment has a strong safety profile. PRP uses your own blood, polynucleotides are highly purified, and Keravive is non-invasive. Side effects are usually limited to short-lived redness or tenderness. Because the injectable steps are doctor-led and follow a proper assessment, risks are kept low.
How the combination compares to each therapy on its own, and to surgery. It also covers what shapes your plan.
PRP on its own concentrates your own growth factors to stimulate weakened follicles, and it is an excellent standalone option. Hair Restore 360 adds two things around it. It brings in a Keravive cleanse to prepare the scalp first, plus polynucleotides to support the surrounding tissue. If your scalp is already healthy, PRP alone may be enough. If you want the fuller reset, the combination does more in one visit.
Polynucleotides focus on repairing and regenerating the scalp tissue, improving the ground your follicles grow in. Hair Restore 360 keeps that benefit and adds PRP stimulation and a deep scalp cleanse. Choose polynucleotides alone if scalp quality is your main concern, or the combination if you also want direct follicle stimulation.
HydraFacial Keravive cleanses, exfoliates and nourishes the scalp, which is ideal if congestion, flaking or product build-up is your issue. It does not stimulate follicles the way injections do. Hair Restore 360 uses Keravive as the first step. It then layers PRP and polynucleotides on top for a more complete result.
These are different tools for different stages. A hair transplant surgically moves follicles and suits advanced or well-established baldness. Hair Restore 360 is non-surgical and works best for early to moderate thinning where follicles are still active. It is not a replacement for surgery, though it can be a useful complement to keep the surrounding hair healthy. Dr Joney De Souza will tell you honestly which fits your situation.
It suits men and women noticing early to moderate thinning, while their follicles are still active. Signs include a widening parting, a finer ponytail or more shedding than usual. It also helps if a congested scalp needs resetting before other treatment. Suitability is confirmed at a face-to-face assessment.
Hair Restore 360 is not the right choice for advanced or complete baldness with very few remaining follicles. In those cases a hair transplant is likely to serve you better. It may also be delayed or avoided with an active scalp infection or certain blood disorders. Treatment may also wait where a medical cause behind your hair loss needs investigating first. We assess everyone before starting.
Because it is a bespoke combination, the price reflects the size of the area treated. It also depends on how many of the three therapies your plan uses. The final factor is whether you have a single session or a course. Each therapy is costed individually. As a guide, the components start from £360 for Keravive, £410 for polynucleotides and £490 for PRP. Your full plan is quoted in writing at your assessment.
Most patients follow a course of three sessions spaced about a month apart. This gives the follicles time to respond between visits. After the course we review your progress and plan maintenance, often every few months. The schedule is tailored to your response rather than fixed.
Downtime is minimal. Expect possible mild redness or tenderness for a day or two. Follow simple aftercare: no hair washing for 24 hours, and no strenuous exercise, swimming or direct sun for 48 hours. Most people go back to normal activities the same day.
You can enquire through the WhatsApp button on this page. You can also ask our team to arrange a consultation at the Marylebone clinic. Because Hair Restore 360 is bespoke, we start with a face-to-face scalp assessment. We then confirm your plan and costs in writing before anything is booked.
The treatment is well tolerated. PRP is drawn from your own blood, polynucleotides are highly purified, and Keravive is non-invasive, so serious reactions are rare. The most common side effects are temporary redness, mild swelling or tenderness at the injection sites. Having the injectable steps performed by a doctor after a proper assessment keeps risk low.
Yes, in many cases. Hair Restore 360 sits comfortably alongside topical treatments such as minoxidil and doctor-prescribed options. It is often used to support them rather than replace them. Always tell us what you are already using at your assessment, so your plan is safe and well coordinated.
Our patients return to us year after year for natural, balanced results. Every review reflects our commitment to precision, safety and a personalised approach to aesthetic care.
I came for PRP hair loss treatment and so far really pleased with the results, have a few more sessions to go. Great clinic and lovely team.
I recently had a HydraFacial with Roma and the results have been nothing short of amazing. Roma was professional and knowledgeable. She took the time to understand my skincare concerns and explained the treatment thoroughly.
Had my second session of PRP with micro needling today and I am so far very happy with my results. Dr De Souza is just the kindest man who really has the best intentions for you.
I highly recommend Dr. Joney and his clinic. I have been his patient for many years and he is definitely one of the best. His work is natural and subtle, and he always puts the patient’s interest first and will never try to upsell unnecessary treatments.