Hair Restore 360 in Marylebone, London

Hair Restore 360 is our doctor-led combination for early hair thinning in London, pairing a HydraFacial Keravive scalp cleanse with PRP and polynucleotide injections to help reduce shedding and support denser, healthier hair over a course.

Hair Restore 360

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Procedure time
75 to 90 minutes
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Back to work
Same day to 48 hours
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Sessions
Course of 3, spaced monthly
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Anaesthetic
Topical numbing
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Sensitivity period
24 to 72 hours
Pricing
On consultation
Bespoke combination, priced individually at consultation.

Who Is Hair Restore 360 For?

Hair Restore 360 at Dr Joney De Souza Clinic is designed for men and women who are noticing early hair thinning and want to act while their follicles are still active and responsive. Perhaps your parting looks a little wider than it did a year ago, your ponytail feels finer in your hand, or you are simply seeing more strands than usual in the shower. This is exactly the stage at which a combined, regenerative approach tends to help most, and it is a genuinely positive moment to take charge of your hair’s long-term health rather than sit and worry.

  • Early to moderate thinning across the crown, temples or parting
  • Men and women with pattern (androgenetic) thinning
  • Diffuse shedding, including post-partum shedding once cleared with your GP
  • A congested, flaky or product-heavy scalp that needs resetting first
  • Anyone who wants a considered, evidence-based plan rather than a single quick fix

There is an honest limit to what any regenerative treatment can achieve, and we would far rather say so at the very start than promise more than we can deliver. Hair Restore 360 is not a substitute for a hair transplant, so where baldness is advanced or complete and very few follicles remain, surgery is likely to serve you better. Dr Joney De Souza will tell you that plainly rather than sell a course that cannot help you. Some hair loss also has a medical cause, from thyroid changes to iron deficiency, so we assess carefully first and, where needed, ask you to see your GP for blood tests before we begin.

What Is Hair Restore 360?

Hair Restore 360 is the clinic’s most comprehensive regenerative hair treatment, bringing three complementary therapies together in a single, carefully sequenced appointment. The session opens with a HydraFacial Keravive scalp cleanse that clears, exfoliates and nourishes the scalp to prepare a healthy environment for growth. Next comes platelet-rich plasma (PRP), drawn and concentrated from your own blood so that your own growth factors can be delivered directly to weakened follicles. Polynucleotides, a purified regenerative gel, then help repair the scalp tissue and improve the environment in which hair grows.

Used together, these three steps do something that no single treatment quite matches on its own. The scalp is cleansed and prepared, the follicles are stimulated, and the surrounding tissue is supported, all within one coordinated plan. Our aim is gentle and realistic, because we want to reduce shedding, improve density and thickness, and support healthier, stronger hair steadily over a course. It suits both men and women in the earlier stages of thinning.

Hair Restore 360 also sits within our wider, longevity-minded approach to scalp and hair health, where the scalp is treated as living skin worth caring for over the years ahead. Rather than chasing one dramatic moment, we focus on steadily investing in the condition of your scalp so that healthy growth has the best possible foundation for the future.

How Does Hair Restore 360 Work?

Each of the three therapies targets a different part of the same underlying problem, which is precisely why combining them works so well in one visit. The Keravive step uses a gentle vortex system to lift away dead skin, excess oil and product build-up before flooding the follicles with a nourishing growth-factor serum. A clean, well-conditioned scalp then absorbs everything that follows far more effectively.

PRP does the stimulating, and we concentrate the platelets in a small sample of your blood before placing that plasma carefully into the thinning areas. Its growth factors signal to resting follicles and coax them back toward an active growth phase while improving circulation around each root. Polynucleotides then do the repairing, because this purified gel calms the scalp and helps rebuild the surrounding tissue so the follicles sit in healthier ground.

Key Benefits

  • Helps reduce excess shedding over a course of treatment
  • Supports improved hair density and thickness in the treated areas
  • Cleanses and rebalances a congested or flaky scalp
  • Stimulates weakened follicles using your own growth factors
  • Improves the scalp environment so new growth is better supported
  • Non-surgical, with little to no downtime for most patients
  • A doctor-led plan tailored to your pattern of thinning, not a one-size protocol
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Step 1: Scalp assessment and Keravive cleanse

Every appointment opens with a close look at your scalp and pattern of thinning. One of our trained practitioners then carries out the HydraFacial Keravive cleanse. A vortex handpiece exfoliates the scalp, clears congestion around the follicles and infuses a nourishing serum. This step takes around 20 minutes and leaves the scalp primed for the injectable stages.

Step 2: Blood draw and PRP preparation

Dr Joney De Souza draws a small sample of blood from your arm. The volume is similar to a routine blood test. The sample spins in a centrifuge for about 10 minutes, which separates and concentrates the platelet-rich plasma ready for use. Most patients feel only the brief pinch of the draw itself.

Step 3: Scalp numbing

A topical numbing cream is applied across the treatment area and left to take effect. This makes the injection stages very comfortable. Most people describe the sensation that follows as light pressure rather than pain. We never rush this part.

Step 4: PRP and polynucleotide injections

Dr Joney De Souza places the PRP into the thinning zones with a fine needle, in an even grid. He then follows with the polynucleotide injections to support the scalp tissue. Performing both in one visit is what makes this a true combination. The stage usually takes 30 to 40 minutes, depending on the size of the area.

Step 5: Aftercare, take-home spray and results timeline

A brief scalp massage settles everything into place, and you leave with a take-home Keravive scalp spray and written aftercare. Mild redness or tenderness is normal for a day or two. A little extra shedding in the first few weeks is expected as follicles reset. Results build gradually, with most patients reviewing progress after their three monthly sessions.

Your Hair Restore 360 Journey at Dr Joney De Souza Clinic

No two scalps thin in quite the same way, so every Hair Restore 360 plan begins with a face-to-face assessment in Marylebone before any treatment is booked. From there, most patients follow a course of three sessions spaced roughly a month apart, with a review afterwards to help decide on gentle maintenance. Here is what to expect at each stage of the journey.

Before Your Treatment

As advised at your consultation, avoid blood-thinning supplements for a week beforehand, where it is medically safe. That includes fish oil, high-dose vitamin E and aspirin. Arrive with clean, product-free hair. A good night’s sleep and a normal meal make the blood draw easier. If anything about your health has changed since your assessment, tell us on arrival.

During Your Session

A full session runs 75 to 90 minutes from start to finish. It moves through the Keravive scalp cleanse, the blood draw and PRP preparation, and topical numbing. Dr Joney De Souza then performs the PRP and polynucleotide injections. The team checks your comfort throughout and can pause at any point. Most patients find the numbing makes the injections easy to tolerate.

After Your Treatment

Leave the scalp to settle and avoid washing your hair for 24 hours. Then skip vigorous exercise, swimming and direct sun for 48 hours. Mild redness or tenderness usually fades within a day or two. A little extra shedding in the first few weeks is normal and not a cause for worry. Resting hairs make way for new growth. Use your take-home scalp spray as directed to extend the benefit between sessions.

Why Dr Joney De Souza Clinic?

Dr Joney De Souza is an experienced aesthetic physician based in Marylebone, in the heart of Central London, and Hair Restore 360 is very much a doctor-led combination. The PRP and polynucleotide injections are performed by Dr Joney De Souza himself, while the HydraFacial Keravive scalp cleanse is delivered by the clinic’s trained practitioners under his medical oversight. Our clinic holds a 4.9 rating from more than 270 verified Google reviews, and careful assessment is the thread that runs through everything we do.

  • Doctor-led injectable steps, not delegated to non-medical staff
  • A face-to-face scalp assessment before any course is agreed
  • Central Marylebone and Harley Street location, easy to reach across London
  • Honest guidance on whether a combination, a single therapy or a referral suits you best

A Medical Standard of Care

Managing expectations matters to us as much as the treatment itself, because Hair Restore 360 works best for early to moderate thinning. Results build steadily over a course rather than overnight, and gentle ongoing maintenance is what protects and extends those gains over time. If your hair loss is advanced, or if we suspect a medical cause behind it, we will say so honestly and then point you toward the right option, whether that is a hair transplant or a check with your GP.

“I never start with a needle. I start by looking at the scalp, the pattern of the thinning and your history, and only then do I decide whether one therapy or a combination gives you the best chance of a genuine improvement. If I do not think it will help you, I will say so.” Dr Joney De Souza

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Hair Restore 360 Pricing in London

Hair Restore 360 is priced on consultation rather than as a fixed package, because it is a genuinely bespoke combination and the three therapies are costed individually. Your plan is shaped around how much thinning you have, the size of the area treated and how your scalp responds over time. Most patients begin with a course of three sessions spaced monthly, then move to occasional maintenance that supports the long-term health of the scalp. Your exact costs are confirmed in writing at your assessment, with no obligation to proceed.

Which Option Is Right for You?

  • Choose the full Hair Restore 360 combination if you want the scalp cleansed, the follicles stimulated and the tissue supported. This is all done in one coordinated plan.
  • Consider PRP for Hair on its own if your scalp is already healthy and stimulation is the priority.
  • Consider Polynucleotides (Plinest Hair) on its own if scalp quality and tissue repair are your main concern.
  • Start with HydraFacial Keravive alone if you mainly need to reset a congested or flaky scalp before deciding on more.

What Hair Restore 360 includes

Everything a single Hair Restore 360 session covers, and what each step does for your scalp.

Treatment1 session (£)3 session (£)

Hair Restore

1300

3600

All three therapies are combined in one appointment and priced individually at consultation.
Not sure? WhatsApp us for advice

Exploring Your Options for Hair Loss?

Hair Restore 360 is one route among several, and the right starting point really depends on your scalp and your goals. Our Hair Health hub sets out every hair treatment we offer side by side, from PRP to scalp-focused care, so you can compare them calmly before your assessment. If you are still weighing things up, that is a good place to begin.

Explore all hair treatments
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Frequently Asked Questions

Common questions we hear about Hair Restore 360 at our Marylebone clinic. If yours is not covered here, ask us at your assessment or over WhatsApp.

What is Hair Restore 360?

Hair Restore 360 is our most comprehensive regenerative hair treatment. It combines three therapies in one appointment: a HydraFacial Keravive scalp cleanse and platelet-rich plasma (PRP) from your own blood. It also uses polynucleotides to support the scalp tissue. The goal is to reduce shedding and support denser, healthier hair over a course.

How many sessions of Hair Restore 360 will I need?

Most patients start with a course of three sessions, spaced about a month apart. We then review your progress and plan any maintenance. The exact number depends on how much thinning you have and how your scalp responds. This is why we assess first.

When will I see results from Hair Restore 360?

Regenerative hair treatment works gradually. Early changes in scalp condition can show within a few weeks. Improvements in density and thickness tend to build over three to six months as follicles move through new growth cycles. Results vary from person to person.

Is Hair Restore 360 painful?

Most patients find it very manageable. The Keravive cleanse is relaxing, and a topical numbing cream is applied before the injections. The PRP and polynucleotide stages usually feel like light pressure rather than pain. Tell us at any point if you need a break.

How much does Hair Restore 360 cost in London?

Hair Restore 360 is priced on consultation, because it is a bespoke combination costed individually rather than a fixed package. As a guide, the component treatments start from £360 for a Keravive scalp cleanse. Polynucleotides start from £410 and PRP from £490. Your exact plan is confirmed in writing at your assessment.

Is there any downtime after Hair Restore 360?

There is little downtime for most people. You may have mild redness or tenderness for a day or two. We ask you to avoid washing your hair for 24 hours. Also skip strenuous exercise, swimming and direct sun for 48 hours. Most patients return to work the same day.

Who performs Hair Restore 360?

It is a doctor-led combination. Dr Joney De Souza performs the PRP and polynucleotide injections. One of our trained practitioners delivers the HydraFacial Keravive scalp cleanse under medical oversight. The plan itself is set by the doctor after your assessment.

Is Hair Restore 360 suitable for men and women?

Yes. Hair Restore 360 suits both men and women in the earlier stages of thinning, including pattern thinning and diffuse shedding. Post-partum shedding can also respond well once cleared with your GP. We confirm suitability at your face-to-face assessment.

Why am I shedding more after my first session?

A little extra shedding in the first few weeks is normal and expected. As follicles reset and enter a new growth phase, some resting hairs are released. This makes way for stronger new growth. This settles as the course progresses, and it is not a sign the treatment is failing.

How long do the results last?

Results do not last forever, because hair thinning is an ongoing process. Most patients maintain their improvement with occasional top-up sessions after the initial course, typically every few months. Your scalp assessment guides how often maintenance is worthwhile for you.

Is Hair Restore 360 safe?

The treatment has a strong safety profile. PRP uses your own blood, polynucleotides are highly purified, and Keravive is non-invasive. Side effects are usually limited to short-lived redness or tenderness. Because the injectable steps are doctor-led and follow a proper assessment, risks are kept low.

Hair Restore 360 vs Other Hair Treatments

How the combination compares to each therapy on its own, and to surgery. It also covers what shapes your plan.

Hair Restore 360 vs PRP alone: what is the difference?

PRP on its own concentrates your own growth factors to stimulate weakened follicles, and it is an excellent standalone option. Hair Restore 360 adds two things around it. It brings in a Keravive cleanse to prepare the scalp first, plus polynucleotides to support the surrounding tissue. If your scalp is already healthy, PRP alone may be enough. If you want the fuller reset, the combination does more in one visit.

Hair Restore 360 vs polynucleotides alone: which should I choose?

Polynucleotides focus on repairing and regenerating the scalp tissue, improving the ground your follicles grow in. Hair Restore 360 keeps that benefit and adds PRP stimulation and a deep scalp cleanse. Choose polynucleotides alone if scalp quality is your main concern, or the combination if you also want direct follicle stimulation.

Hair Restore 360 vs HydraFacial Keravive alone: what does each do?

HydraFacial Keravive cleanses, exfoliates and nourishes the scalp, which is ideal if congestion, flaking or product build-up is your issue. It does not stimulate follicles the way injections do. Hair Restore 360 uses Keravive as the first step. It then layers PRP and polynucleotides on top for a more complete result.

Hair Restore 360 vs a hair transplant: which is right for me?

These are different tools for different stages. A hair transplant surgically moves follicles and suits advanced or well-established baldness. Hair Restore 360 is non-surgical and works best for early to moderate thinning where follicles are still active. It is not a replacement for surgery, though it can be a useful complement to keep the surrounding hair healthy. Dr Joney De Souza will tell you honestly which fits your situation.

Who is Hair Restore 360 best suited to?

It suits men and women noticing early to moderate thinning, while their follicles are still active. Signs include a widening parting, a finer ponytail or more shedding than usual. It also helps if a congested scalp needs resetting before other treatment. Suitability is confirmed at a face-to-face assessment.

Who is Hair Restore 360 not suitable for?

Hair Restore 360 is not the right choice for advanced or complete baldness with very few remaining follicles. In those cases a hair transplant is likely to serve you better. It may also be delayed or avoided with an active scalp infection or certain blood disorders. Treatment may also wait where a medical cause behind your hair loss needs investigating first. We assess everyone before starting.

What determines the price of Hair Restore 360?

Because it is a bespoke combination, the price reflects the size of the area treated. It also depends on how many of the three therapies your plan uses. The final factor is whether you have a single session or a course. Each therapy is costed individually. As a guide, the components start from £360 for Keravive, £410 for polynucleotides and £490 for PRP. Your full plan is quoted in writing at your assessment.

How many sessions are recommended and how are they spaced?

Most patients follow a course of three sessions spaced about a month apart. This gives the follicles time to respond between visits. After the course we review your progress and plan maintenance, often every few months. The schedule is tailored to your response rather than fixed.

What is the downtime after Hair Restore 360?

Downtime is minimal. Expect possible mild redness or tenderness for a day or two. Follow simple aftercare: no hair washing for 24 hours, and no strenuous exercise, swimming or direct sun for 48 hours. Most people go back to normal activities the same day.

How do I book Hair Restore 360 in London?

You can enquire through the WhatsApp button on this page. You can also ask our team to arrange a consultation at the Marylebone clinic. Because Hair Restore 360 is bespoke, we start with a face-to-face scalp assessment. We then confirm your plan and costs in writing before anything is booked.

Is Hair Restore 360 safe, and what are the side effects?

The treatment is well tolerated. PRP is drawn from your own blood, polynucleotides are highly purified, and Keravive is non-invasive, so serious reactions are rare. The most common side effects are temporary redness, mild swelling or tenderness at the injection sites. Having the injectable steps performed by a doctor after a proper assessment keeps risk low.

Can Hair Restore 360 be combined with other hair treatments like minoxidil?

Yes, in many cases. Hair Restore 360 sits comfortably alongside topical treatments such as minoxidil and doctor-prescribed options. It is often used to support them rather than replace them. Always tell us what you are already using at your assessment, so your plan is safe and well coordinated.

4.9 ★★★★★

Read our reviews

Our patients return to us year after year for natural, balanced results. Every review reflects our commitment to precision, safety and a personalised approach to aesthetic care.

I came for PRP hair loss treatment and so far really pleased with the results, have a few more sessions to go. Great clinic and lovely team.

I recently had a HydraFacial with Roma and the results have been nothing short of amazing. Roma was professional and knowledgeable. She took the time to understand my skincare concerns and explained the treatment thoroughly.

Sarah Sabner
Sarah Sabner
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Had my second session of PRP with micro needling today and I am so far very happy with my results. Dr De Souza is just the kindest man who really has the best intentions for you.

I highly recommend Dr. Joney and his clinic. I have been his patient for many years and he is definitely one of the best. His work is natural and subtle, and he always puts the patient’s interest first and will never try to upsell unnecessary treatments.

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Kind words that made our day 🤍

We were so touched to receive this lovely feedback from a recent client following her PicoSure face treatment with Roma - this one’s for David, Roma, and Dr Joney.

“From the moment I arrived, David and Roma made me feel so welcome and completely at ease. Roma was caring, professional, and took the time to explain the treatment thoroughly, making sure I felt comfortable and reassured throughout. Even after just one session, my skin already feels smoother and looks much more refreshed.”

Moments like this are exactly why we do what we do. It’s not just about the results (although we’re so pleased with how her skin is already responding!), it’s about making every client feel genuinely cared for from the second they walk through the door.

Thank you to our amazing client for such kind words, and to David, Roma, and Dr Joney for the warmth and care you bring to every single appointment 🫶HydraFacial: the secret to that red-carpet glow ✨

Ever wondered what actually happens during a HydraFacial? Here’s a look inside the treatment, step by step, at Dr Joney De Souza.

It begins with a deep cleanse and exfoliation to clear away impurities and prepare the skin, followed by gentle extractions that refine congestion with complete comfort and precision. 

From there, targeted serums and boosters are infused into the skin, tailored entirely to your individual needs, before LED light therapy supports the skin’s long-term health and renewal. 

The treatment finishes with an antioxidant infusion, sealing in radiance for that lit-from-within finish.

This particular treatment was our Deluxe HydraFacial, though for those wanting to elevate the experience further, our Platinum HydraFacial also includes lymphatic drainage, perfect for extra de-puffing and detoxification alongside all the usual glow-boosting benefits.

The result is skin that looks cleansed, replenished, and effortlessly glowing, delivered with the precision and care that defines every treatment here.

📍 Marylebone, London | 020 7043 0748 📱Sculptra vs Juläine: which biostimulator is right for you? 💭

Both Sculptra and Juläine are poly-L-lactic acid (PLLA) biostimulators - meaning rather than simply adding volume, they work by encouraging your skin to produce its own natural collagen over time, for results that look and feel truly you.

Sculptra is the original PLLA injectable, with a long-established track record for stimulating collagen and improving skin structure and firmness gradually over several months, with results that can last up to two years.

Juläine is a newer generation PLLA treatment, using more uniform, highly purified microspheres engineered to mix more evenly, which can help reduce inflammation caused by treatment. Like Sculptra, results build gradually, with visible improvements from a few weeks in and full effects developing over a few months. 

Both are excellent options for restoring facial volume, improving skin quality, and softening lines. The right choice really depends on your skin, goals, and what your practitioner recommends for you.

Not sure which is best suited to your skin and goals? Get in touch with us today to book your consultation.

📍Marylebone, London | 020 7043 0748 📱Product Spotlight | Daily Power Defense ✨

ZO Skin Health’s Daily Power Defense is one of those products that quietly does a lot of the heavy lifting in a skincare routine, and it’s become a firm favourite of ours here at the clinic.

Formulated with Vitamins A and E, it helps protect the skin against environmental damage and free radicals, while supporting barrier restoration and long-lasting hydration.
Over time, this can mean fewer visible signs of premature ageing and a stronger, more resilient complexion.

It’s a lightweight daily step, but one that adds up - the kind of product that supports your skin quietly in the background, day after day.

If you’re curious whether it fits into your routine, drop us a DM, or ask at your next appointment 📅Where your journey begins 🤍

Welcome to Dr Joney De Souza Skin & Laser - this is the first thing you’ll see when you walk through our doors.

We know that coming in for an aesthetic treatment for the first time can feel daunting. Questions about what to expect, nerves about the treatment itself, uncertainty about whether it is the right decision, these are all completely normal, and we never take that lightly.

That is why the environment we have created here matters so much to us.

Our clinic is clean, safe, and held to the highest clinical standards, because when it comes to your skin and your health, that is non-negotiable. But we never wanted it to feel cold, clinical, or intimidating. We wanted it to feel like somewhere you could genuinely relax, from the very first moment you arrive.

That is why alongside everything you would expect from a leading skin and laser clinic, you will also find the kind of touches that make a space feel like somewhere you actually want to be. Picture frames. Mirrors. Magazines. Reed diffusers. The small details that take the edge off and remind you that while you are in expert hands, you are also somewhere that genuinely cares about how you feel, not just how your skin looks.

Because great results start with feeling comfortable enough to be yourself, ask your questions, and trust the people looking after you.

We cannot wait to welcome you, or welcome you back 🫶

How can you find us?

Our clinic is located in Marylebone, London, in the heart of one of Central London’s most prestigious and renowned medical districts. Perfectly positioned for convenience and discretion, we are easily accessible from across the capital and beyond.

We welcome patients from Mayfair, Harley Street, Marylebone, Knightsbridge, Belgravia, Chelsea, Kensington, Fitzrovia and St John’s Wood, as well as international patients visiting London for specialist treatment.

Our location benefits from excellent transport connections, with close proximity to major Underground stations, mainline rail links and direct access to Heathrow, Gatwick and London City airports. Several secure parking facilities and convenient chauffeur drop-off points are available nearby, ensuring a seamless and comfortable visit.

Whether you are travelling from elsewhere in London, across the UK or internationally, our clinic offers a calm, private and exclusive setting in one of the world’s leading medical destinations.

Opening hours
Monday
9 am to 6 pm
Tuesday
9 am to 6 pm
Wednesday
9 am to 6 pm
Thursday
9 am to 6 pm
Friday
9 am to 6 pm
Saturday
Closed
Sunday
Closed
Dr Joney De Souza
49 Blandford St, London W1U 7HH
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