Is PicoSure Laser Safe? A London Doctor Reviews the Evidence

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Is PicoSure Laser Safe? A London Doctor Reviews the Evidence

At Dr Joney De Souza Skin & Laser in Marylebone, people considering pigmentation or tattoo treatment often ask: is PicoSure safe? It is a fair question, and the evidence is encouraging. PicoSure is a 755 nm picosecond laser, and studies report a strong safety profile, including in darker skin tones. Below, we review what the research shows, the side effects to expect, and how we keep treatment safe.

At Dr Joney De Souza, we run PicoSure Pro with both of its wavelengths, and we fit the Focus lens, so rejuvenation is part of what the platform does here and not only pigment clearance. We also include around 30 minutes of numbing and a full 45-minute treatment, rather than a rushed 15-minute session with no numbing. In practice, that means a more thorough and more comfortable treatment.

Key takeaways

  • Studies describe the 755 nm picosecond laser as safe and effective, with minimal side effects.
  • Most reactions are brief redness and swelling that settle within hours to a day.
  • Research in darker skin reports no permanent change in pigment when used correctly.
  • Its ultra-short pulses are gentler on the skin than older Q-switched lasers.

What Does the Clinical Evidence Say?

PicoSure has been studied in dermatology journals, including in skin of colour. A 2020 review in Dermatologic Surgery treated darker skin types for pigmentation. The authors found significant improvement and reported no permanent loss or gain of pigment. In short, the treatment was well tolerated.

Why Picosecond Pulses Are Gentler

The picosecond laser delivers energy in trillionths of a second. As a result, it shatters pigment with a photomechanical effect and less heat. Because there is less heat, the surrounding skin is better protected. For this reason, picosecond lasers carry a lower risk than older nanosecond devices. To explore the treatment, see our PicoSure laser page.

What Side Effects Can PicoSure Cause?

No treatment is entirely free of effects, so honesty matters. After PicoSure, most reactions are brief and mild. Typically, patients notice the following.

  • Redness and mild swelling, often settling within a day
  • Temporary darkening of pigment before it flakes away
  • A warm, tingling sensation during treatment
  • Rarely, short-lived lightening or darkening of the skin

Generally, these effects are short-lived. Importantly, studies in Asian skin report transient erythema that resolves quickly. This makes PicoSure a considered choice for pigmentation across a range of skin tones.

How We Keep PicoSure Safe at Our Clinic

Safety is about the operator as much as the laser. At our Marylebone clinic, several steps protect you.

  • A doctor-led consultation assesses your skin type and pigment first.
  • We tailor the settings to your skin, which lowers the pigmentation risk.
  • A patch test may be used before treating sensitive or darker skin.
  • Clear aftercare and daily sun protection support your result.

As a result, side effects stay minimal and brief. Moreover, every plan is matched to your skin and your goals.

Who Should Not Have PicoSure?

PicoSure is not suitable for everyone. We avoid treatment during pregnancy or breastfeeding. Equally, it is unsuitable over active infections, recent sun tan, or with certain photosensitive conditions. A consultation confirms whether it is right for you.

Book a Doctor-Led PicoSure Consultation in Marylebone

At Dr Joney De Souza Skin & Laser, every PicoSure treatment is doctor-led. To learn more, visit our PicoSure laser page and our prices list. Alternatively, book a consultation.

Clinical references

  1. Koh, Tan, Chua. Treatment of laser-responsive dermal pigmentary conditions in Type III-IV Asian skin with a 755-nm picosecond pulse duration laser: a retrospective review of its efficacy and safety. Dermatologic Surgery. 2020;46(11). PMC
  2. Hu S, Yang CS, Chang SL, Huang YL, Lin YF, Lee MC. Efficacy and safety of the picosecond 755-nm alexandrite laser for treatment of dermal pigmentation in Asians: a retrospective study. Lasers in Medical Science. 2020;35(6):1377-1383. PubMed
  3. Zhou et al. Safety and efficacy of a picosecond 755-nm alexandrite laser combined with topical tranexamic acid in the treatment of melasma. Journal of Cosmetic Dermatology. 2024. doi:10.1111/jocd.16432

Book PicoSure at Dr Joney De Souza

At Dr Joney De Souza Skin & Laser in Marylebone, every treatment is doctor-led and tailored to you. To discuss your goals and see current pricing, explore the treatment page or book a consultation with our team.

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PicoSure FAQs

Common questions our Marylebone team hears about this treatment.

Is PicoSure safe?

Peer-reviewed studies describe the 755 nm picosecond laser as safe and effective, with minimal, short-lived side effects when used by a trained clinician.

Is PicoSure safe for darker or Asian skin?

Yes. Studies in Type III to IV skin report good results with no permanent pigment change, as the settings are tailored to the skin.

What are the side effects of PicoSure?

Most patients notice only brief redness, mild swelling and temporary darkening of pigment that flakes away over a few days.

Does PicoSure hurt?

Treatment feels like a warm, tingling snap. A numbing cream can be used to keep you comfortable if needed.

How long do PicoSure side effects last?

Redness and swelling usually settle within hours to a day. Any pigment darkening flakes away over several days.

Is PicoSure safer than older lasers?

Its picosecond pulses deliver energy with less heat than older nanosecond lasers, which lowers the risk of pigment-related side effects.

Can PicoSure cause pigmentation problems?

Temporary changes can occur, but studies report no permanent pigment change when the laser is used correctly on suitable skin.

Who should not have PicoSure?

PicoSure is avoided during pregnancy or breastfeeding, over active infections, on freshly tanned skin, or with certain photosensitive conditions.

Is PicoSure FDA cleared?

PicoSure is a recognised, widely used picosecond laser platform. For safety, treatment should always be performed by a qualified clinician.

How can I reduce my risk with PicoSure?

Choose a doctor-led clinic, share your skin history, avoid sun before treatment, and follow the aftercare and SPF advice given.

How can you find us?

Our clinic is located in Marylebone, London, in the heart of one of Central London’s most prestigious and renowned medical districts. Perfectly positioned for convenience and discretion, we are easily accessible from across the capital and beyond.

We welcome patients from Mayfair, Harley Street, Marylebone, Knightsbridge, Belgravia, Chelsea, Kensington, Fitzrovia and St John’s Wood, as well as international patients visiting London for specialist treatment.

Our location benefits from excellent transport connections, with close proximity to major Underground stations, mainline rail links and direct access to Heathrow, Gatwick and London City airports. Several secure parking facilities and convenient chauffeur drop-off points are available nearby, ensuring a seamless and comfortable visit.

Whether you are travelling from elsewhere in London, across the UK or internationally, our clinic offers a calm, private and exclusive setting in one of the world’s leading medical destinations.

Opening hours
Monday
9 am to 6 pm
Tuesday
9 am to 6 pm
Wednesday
9 am to 6 pm
Thursday
9 am to 6 pm
Friday
9 am to 6 pm
Saturday
Closed
Sunday
Closed
Dr Joney De Souza
49 Blandford St, London W1U 7HH
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