PRP Facial Treatment in Marylebone, London

Doctor-led PRP facial at Dr Joney De Souza Clinic, Marylebone. Regenerative treatment using your own blood to boost collagen and radiance. From £490. Book today.

PRP Treatment London

Regenerative treatment using your own blood to stimulate collagen, improve skin texture and restore natural radiance. Doctor-led. No synthetic materials. Minimal downtime.

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No. of treatments
Initially a course of 3 treatments spaced three months apart
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Procedure time
60 minutes
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Back to work
2 days
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Duration of results
Maximum results after 6 months but skin continues to improve over time.
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Anaesthetic
Topical cream
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Sensitivity period
24-72 hours
Price From
£490

Who Is PRP Treatment For?

If your skin has lost the freshness it used to have, looks tired or uneven, or simply no longer bounces back the way it once did, a PRP facial gives your body the signal to repair itself. Most patients at our Marylebone clinic are in their late twenties to early sixties, though age matters far less than what you see in the mirror. People come to us worried about overall skin condition, early signs of ageing and fading radiance, rather than one isolated feature.

Skin Concerns PRP Addresses Well

A PRP facial, often searched for as a vampire facial, works especially well for one or more of the following:

  • Fine lines and early wrinkles around the eyes, mouth and forehead
  • Dull, uneven or sun-damaged skin tone
  • Visible loss of firmness across the lower face or neck
  • Enlarged pores and rough surface texture
  • Dark circles and thinning skin beneath the eyes
  • Decolletage skin that appears crepey or sun-damaged
  • Mild to moderate acne scarring

What PRP Is Best For

PRP is at its best for refreshing and rebuilding skin quality, and because it uses only your own blood there is no risk of allergic reaction. If your priority is restoring lost volume in the cheeks or lips, or lifting heavier jowls and deeper folds, we can combine treatments or guide you to dermal fillers for that. Your practitioner confirms suitability at consultation, and PRP is not recommended if you are pregnant, have an active skin infection at the treatment site, or cannot safely pause blood-thinning medication.

 

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What Is PRP Treatment?

PRP stands for Platelet Rich Plasma. It is a regenerative injectable that uses a highly concentrated preparation of your own plasma to stimulate collagen production, improve skin texture and restore natural radiance.

A small blood sample is drawn at the clinic and spun in a centrifuge to isolate the platelet-rich fraction. That concentrated preparation carries a high level of growth factors. Once injected into targeted areas of the face, those growth factors trigger the skin’s natural repair and renewal response.

New collagen forms, circulation improves, and the skin gradually becomes firmer, smoother and more luminous. Results look natural and build over four to eight weeks after each session, so the change reads as you looking rested rather than treated.

Related treatments at Dr Joney De Souza: PRF, PRP for hair loss and exosome therapy.

PRP (Platelet-Rich Plasma) Before & After Results in Marylebone

Many patients notice improved skin quality, texture and radiance following a course of PRP treatment. Results develop gradually as growth factors stimulate collagen production and tissue regeneration over the weeks following treatment.

Furthermore, patients using PRP for hair restoration often report reduced shedding and increased hair density after a course of sessions. Individual results vary, and Dr De Souza will advise on realistic outcomes at your consultation.

Before
After
Before
After

How Does PRP Treatment Work?

PRP works by concentrating the growth factors already present in your blood and delivering them into the skin at depth. That sets off a controlled regenerative response, stimulating collagen production, tissue repair and better microcirculation across the treated area. In plain terms, it wakes up the skin’s own repair machinery and puts it to work.

Key Benefits of PRP Treatment

  • Stimulates new collagen and elastin using nothing but your own biology
  • Progressively improves skin firmness, texture and radiance
  • Reduces fine lines and early wrinkles over weeks without surgery
  • Brightens dull, uneven or sun-damaged skin tone
  • Suitable for the face, neck and decolletage in a single session
  • No risk of allergic reaction as treatment uses only your own blood
  • Minimal downtime, with most patients returning to normal activities within 24 hours
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Step 1: Blood draw and preparation

Your practitioner draws a small blood sample from your arm before treatment begins. The volume is similar to a standard blood test and takes only a few minutes. The process is straightforward, and most patients find it very comfortable.

Step 2: Centrifuge processing

The sample then goes into our centrifuge system and spins at high speed. This separates the blood into its component layers, concentrating the platelets and growth factors into a highly active plasma preparation. The result is a consistent, high quality preparation ready for injection.

Step 3: Topical anaesthetic

Once the plasma is ready, your practitioner applies a topical numbing cream across the treatment area and allows it to take full effect before proceeding. Most patients find the injection phase very manageable, and discomfort during PRP injections at our London clinic is minimal.

Step 4: Precise injection

The concentrated PRP is then injected into targeted areas using fine needles. The technique varies by area and concern, with greater precision applied to delicate zones such as the under-eye area or around the mouth. Each session is tailored to your specific skin goals rather than following a standard protocol.

Step 5: Immediate aftercare

After the injections are complete, your practitioner reviews the treated area and gives you specific aftercare guidance. Some redness or minor swelling is normal and typically clears within 24 to 48 hours. Most patients return to their normal activities the following day.

Step 6: Regeneration over weeks

Over the following four to eight weeks, growth factors activate the skin’s collagen-producing cells. New blood vessel formation improves microcirculation, gradually brightening and firming the skin as the regenerative process continues. The full benefit of a course usually becomes visible by the three-month mark.

Your PRP Treatment Journey

First-Time Patients

PRP at Dr Joney De Souza Clinic begins with a full medical consultation. Your practitioner reviews your skin health, medical history and treatment goals to confirm suitability and recommend the right number of sessions. A course of two to three sessions spaced four to six weeks apart usually produces the strongest cumulative result.

If you are new to regenerative treatment, PRP is one of the most accessible starting points. It involves no synthetic material, no significant recovery period, and results that build naturally over weeks rather than appearing overnight.

Ongoing Patients

Once you have completed an initial course, a maintenance session once or twice a year typically sustains the improvements you have achieved. Over time, many patients choose to combine PRP with complementary treatments such as

SkinPen microneedling, polynucleotides or skin boosters as their goals evolve.

Your skin is reviewed at each appointment and the treatment approach is adjusted as your skin changes and matures.

Before treatment

As advised at consultation, avoid blood-thinning medications and alcohol in the days before your appointment where medically appropriate. Staying well hydrated helps ensure a good quality blood draw on the day. Our team will contact you beforehand with any specific preparation instructions relevant to your medical history.

During treatment

PRP treatment takes approximately 45 to 60 minutes in total. Once the topical anaesthetic takes full effect, your practitioner begins the injection sequence. Most patients find the experience very manageable and leave the clinic the same day.

After treatment

Mild redness, swelling or small injection marks are common in the 24 to 48 hours after treatment, and they usually resolve without any specific intervention. We advise avoiding strenuous exercise, saunas and direct sun exposure during this period so the skin heals more efficiently and the regenerative process develops undisturbed.

Why Dr Joney De Souza Clinic?

At Dr Joney De Souza Clinic, PRP is delivered by practitioners with advanced training in regenerative injectables and a thorough understanding of facial anatomy. Carried out by one of our doctors, Dr Joney De Souza or Dr Mattia Parducci. Your consultation is with Dr Joney De Souza or Dr Mattia Parducci. Every patient completes a full medical consultation before treatment begins, a step that confirms suitability, establishes your skin goals and allows the session to be tailored individually rather than applied as a standard protocol.

“My ‘less is more’ approach has become the mainstay of my practice and clients appreciate that they will have natural looking results” Dr Joney De Souza, The Sybarite

Rated 4.9 From Over 272 Google Reviews

Our patients return to us year after year for results that are natural, balanced and genuinely lasting. PRP has been delivered here across thousands of patient sessions, with both the injection technique and the patient journey refined on clinical outcomes rather than trends.

A Medical Standard of Care

Every PRP session at our clinic uses CE-certified preparation equipment, producing a consistently high quality plasma preparation at each visit. Treatment takes place in a medically supervised environment, with full aftercare guidance provided before you leave.

  • Doctor-led aesthetic clinic in Marylebone, central London
  • Full medical consultation before every course of treatment
  • CE-certified PRP preparation equipment used at every session
  • Rated 4.9 from over 272 verified Google reviews
  • Tailored treatment plans reviewed and adjusted at each visit

By pairing PRP with microneedling to support your skin’s own collagen, the aim is not a quick fix but skin longevity, improving quality, texture and glow while helping preserve the skin’s underlying structure over time.

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PRP Treatment Pricing

PRP at Dr Joney De Souza Clinic is priced by the number of areas treated in a single session. Treatment can be applied to the face, neck or decolletage individually, or across two areas in the same appointment for a more comprehensive regenerative result.

Which Areas Can Be Treated?

One-area treatment is the most common starting point and typically covers the full face. If you have visible concerns across the neck or decolletage, combining areas in a single session makes sense. Treating two areas together costs less than separate bookings and gives a more consistent regenerative result across a wider surface.

PRP treatment pricing

Dr Joney (£)Associate Clinician (£)

1 Area (Face OR Neck OR Décolletage)

575

490

2 Areas (Face OR Neck OR Décolletage)

775

660

Final pricing may vary based on your treatment plan and clinical assessment.
Not sure? WhatsApp us for advice

Enhance Your Results with SkinPen Microneedling

SkinPen is an FDA-cleared microneedling device and one of the most clinically validated tools available for skin renewal. At Dr Joney De Souza Clinic, SkinPen is frequently combined with PRP in a single session for patients who want to address texture, scarring and early ageing at the same time. The micro-channels SkinPen creates let PRP reach deeper layers of the skin than topical application achieves alone.

The combined treatment produces a stronger regenerative response than either approach delivers on its own. It suits patients with acne scarring, enlarged pores or uneven skin tone especially well, where surface refinement and deeper collagen stimulation are both needed, and results tend to appear more quickly than after PRP alone. You can read more on our

PRP with SkinPen microneedling page.

The session takes approximately 60 to 90 minutes and recovery is comparable to standalone PRP. Individual suitability depends on your skin concern and current condition. If you would like advice on whether SkinPen with PRP is right for you, WhatsApp our team for a quick recommendation before booking.

Explore SkinPen
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Frequently Asked Questions

Below are the questions patients most commonly ask about PRP treatment for the face. For anything not covered here, WhatsApp our team directly for a quick answer.

How much does a PRP facial cost in London?

At Dr Joney De Souza Clinic in Marylebone, a PRP facial starts from £490 for one area in a single session, with a course of two available from £830. Two-area treatment covering the face plus the neck or decolletage is £660 per session, which costs less than separate bookings. Final pricing depends on the number of areas treated and any additional treatments included in your plan, and your practitioner confirms it at consultation.

What is a PRP facial?

PRP stands for Platelet Rich Plasma, a regenerative injectable that uses a concentrated preparation of your own blood to stimulate collagen production, improve skin texture and restore natural radiance. Often searched for as a vampire facial, it involves drawing a small blood sample, processing it to isolate the platelet-rich plasma, and injecting it into targeted areas of the face. Treatment uses only your own blood, so there is no risk of allergic reaction and no synthetic material involved, and results develop progressively over four to eight weeks as the skin’s repair response takes hold. It is one of the most effective ways to treat dull skin and restore a healthy glow.

How many PRP facial sessions do I need?

Most patients benefit from a course of two to three sessions, spaced four to six weeks apart. Each session builds on the regenerative response triggered by the last, producing a cumulative improvement in skin quality, firmness and radiance. Some patients with more pronounced concerns may benefit from additional sessions as part of a longer plan, which your practitioner discusses at consultation.

Is there any downtime after a PRP facial?

PRP involves minimal downtime, and most patients return to their normal activities the following day. Mild redness, swelling or small injection marks are common in the 24 to 48 hours after treatment and usually resolve without any specific intervention. We advise avoiding strenuous exercise, saunas and direct sun exposure during this period so the skin heals efficiently and the regenerative process develops undisturbed.

When will I see results from a PRP facial?

Most patients notice early improvements in skin texture and radiance within two to four weeks of their first session. Firmer, smoother skin with a more even tone typically becomes visible at six to eight weeks. The full benefit of a course is usually apparent by three months, and a course of two to three sessions typically delivers results lasting twelve to eighteen months. A maintenance session once or twice a year is usually enough to sustain the improvements you have achieved.

Is a PRP facial safe?

PRP is one of the safest treatments available in aesthetic medicine because it uses nothing but your own blood. There is no synthetic material, no donor tissue and no risk of allergic reaction. CE-certified preparation equipment is used at every session, producing a consistently high quality plasma preparation. As with any injectable treatment, there is a small risk of bruising or temporary redness, which typically resolves within 48 hours.

What is the difference between PRP and PRF?

PRP and PRF both use your own blood, but they are prepared differently and behave differently in the skin. PRF (Platelet Rich Fibrin) is spun more slowly and without additives, so it forms a natural fibrin scaffold that releases growth factors gradually over several days, whereas PRP delivers a more immediate concentration. Your practitioner selects the right option for your skin at consultation. You can compare our full regenerative range through the PRP and PRF hub, or read more about PRF and PRP for hair loss.

Can I combine a PRP facial with microneedling?

Yes, and combining PRP with microneedling often produces a stronger result than either treatment alone. PRP is frequently paired with SkinPen microneedling, where the micro-channels enhance PRP absorption and amplify collagen stimulation. It works particularly well for acne scarring, enlarged pores and uneven skin tone, where surface refinement and deeper collagen stimulation are both needed. You can read more about the combined treatment on our PRP with SkinPen microneedling page, or explore the exosome treatment for another regenerative option.

Who performs the PRP facial at Dr Joney De Souza Clinic?

Carried out by one of our doctors, Dr Joney De Souza or Dr Mattia Parducci. Your consultation is with Dr Joney De Souza or Dr Mattia Parducci. Your practitioner assesses you for suitability before treatment begins and refines the injection technique to your individual anatomy rather than applying a standard protocol. Because the quality of PRP depends heavily on the preparation system and the skill of the practitioner, this doctor-led approach at our Marylebone clinic gives you a consistent, medical standard of care.

How do I book a PRP facial in Marylebone?

You can contact us by WhatsApp, phone or email, or you can book your treatment online. Dr Joney De Souza Clinic is in Marylebone, central London, within easy reach of Bond Street, Baker Street and Marble Arch tube stations. Every course begins with a full medical consultation, so your practitioner confirms your suitability and treatment plan before any PRP facial goes ahead.

4.9 ★★★★★

Read our reviews

Our patients return to us year after year for natural, balanced results. Every review reflects our commitment to precision, safety and a personalised approach to aesthetic care.

I’m absolutely thrilled with the results of my HydraFacial at Dr. Joney De. Suza’s clinic. I was so impressed that I’ve already booked my next appointment and can’t wait to make it a regular part of my routine. I’ve also been raving about it to all my girlfriends. Best, Trisha S
I recently had the “HydraFacial” treatment and I can honestly say it was one of the best facial treatments I have ever had. It was my first time to the clinic after many recommendations. The space is beautiful and calming. The team made me feel so welcome and talked me through every step of the treatment which was carried out using only the best products and equipment. I left the clinic with the most glowing skin and I could clearly see the results even after only one treatment. I could not recommend this clinic enough. Thank you again!
Sarah McGovern
Sarah McGovern
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I recently had a HydraFacial with Roma and the results have been nothing short of amazing. I was impressed by the modern, pristine clinic and the warm, welcoming staff. Roma, the aesthetician, was professional and knowledgeable. She took the time to understand my skincare concerns and explained the HydraFacial process in detail. The treatment itself was fantastic and over the next few days my skin was noticeably smoother and more even toned. She also provided sound aftercare advice, telling me how I can reduce my overall skincare budget at home whilst improving results — so no upsell just solid pro experience on what works best.
Sarah Sabner
Sarah Sabner
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I genuinely wouldn’t trust anyone else with my skin. Dr Joney de Souza remains my top recommendation for anyone seeking expert aesthetic care in London. He has a calm, professional manner and always takes the time to truly listen and understand what you’re hoping to achieve. His approach is natural and refined, you always leave looking like the best version of yourself, never overdone. The clinic is a beautiful, welcoming space in the heart of London, and the entire team is warm, knowledgeable, and highly professional. Dr Joney’s expertise and eye for detail are truly exceptional, and the results speak for themselves.
Daniele Bernardinetti
Daniele Bernardinetti
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Profhilo vs Profhilo Structura - what is the difference? 👉

Both are injectable treatments containing hyaluronic acid. Both are produced by the same manufacturer. And both deliver beautiful, natural results. But they are not the same treatment, and understanding the difference is important when it comes to choosing the right one for your skin.

🫧 Profhilo
Profhilo is a skin booster. Its primary purpose is to deeply hydrate the skin, improve overall skin quality and stimulate the production of collagen and elastin. It spreads through the tissue to treat a wide area, leaving the skin looking more radiant, plump and youthful. It is suitable for a broad range of patients and is particularly effective for anyone experiencing dullness, dehydration or a general loss of skin glow.

🫧 Profhilo Structura
Profhilo Structura is specifically designed to address skin laxity and loss of firmness. It contains a higher concentration of high molecular weight hyaluronic acid, which works to remodel the deeper structural layers of the skin, restoring lift, firmness and definition in areas where the skin has begun to lose its architecture over time. It is particularly effective for the cheeks, jawline and neck.

Which one is right for you?
If your primary concern is skin quality, hydration and radiance, Profhilo is likely the right starting point. If you are noticing a loss of firmness, definition or lift, Profhilo Structura may be the more appropriate choice. For many patients, the two work beautifully together as part of a combined treatment plan.

The best way to find out is a thorough consultation with one of our medics 🤍Your guide to radiant summer skin ☀️

Summer is here, and your skin needs a little extra love. Swipe through for everything you need to know to keep your skin glowing all season long 👉

PicoSure targets pigmentation, sun damage and uneven skin tone at a cellular level - giving you a clearer, brighter complexion just in time for summer.

SPF 50, every single day. Non-negotiable. UV rays are present rain or shine, and no treatment or product can undo the damage of unprotected sun exposure. Apply every morning and reapply every two hours outdoors. 

Skin boosters deliver deep hydration from within - improving elasticity, smoothing texture and creating that natural, lit-from-within glow that no topical product can replicate. 

📍Marylebone, London | 020 7043 0748 📱A Wonderful Review for Roma ✨

At Dr. Joney De Souza Skin & Laser Clinic, we believe that exceptional results are achieved through expertise, personalised care, and a genuine commitment to every patient’s journey.

We are delighted to share this wonderful feedback for Roma, whose knowledge, skill, and thoughtful approach continue to make a lasting impact on those she treats.

Roma takes the time to understand each individual’s skin concerns and goals, creating tailored treatment plans that deliver beautiful, confidence-boosting results. Her warm and professional manner ensures every patient feels comfortable, informed, and in the safest of hands throughout their journey.

Roma, thank you for the dedication and care you bring to every appointment. We are incredibly proud to have you as part of the clinic.

And to our lovely client, Victoria, thank you for your kind words and for trusting us with your skin health. We are thrilled that you achieved such great results and look forward to welcoming you back soon 🫶If you read one thing today, please let it be this 🤍

July is UV Safety Awareness Month, and as a skin and laser clinic, there is genuinely nothing we feel more passionately about than protecting the skin you’re in.

UV radiation is the leading cause of skin cancer worldwide. UVA rays silently penetrate deep into the skin every single day - breaking down collagen, causing dark spots, wrinkles and long-term cellular damage - while UVB rays trigger the DNA mutations that lead to skin cancer. And they are both present even on overcast days in the UK.

The reality? Nearly 9 in 10 melanomas are preventable. That statistic is both sobering and empowering because it means the choices you make today genuinely matter.

Swipe through for everything you need to know about why UV protection is non-negotiable, what unprotected exposure is doing to your skin right now, and exactly how to protect yourself this summer and beyond...

SPF 50 every morning. A wide-brimmed hat. Shade between 10am and 4pm. UV-blocking sunglasses. Lightweight cover-up. These aren’t just suggestions, they’re the steps that protect your skin, your health and your future 🖤

#uvsafety #uvsafetyawarenessmonth #melanomaawareness

How can you find us?

Our clinic is located in Marylebone, London, in the heart of one of Central London’s most prestigious and renowned medical districts. Perfectly positioned for convenience and discretion, we are easily accessible from across the capital and beyond.

We welcome patients from Mayfair, Harley Street, Marylebone, Knightsbridge, Belgravia, Chelsea, Kensington, Fitzrovia and St John’s Wood, as well as international patients visiting London for specialist treatment.

Our location benefits from excellent transport connections, with close proximity to major Underground stations, mainline rail links and direct access to Heathrow, Gatwick and London City airports. Several secure parking facilities and convenient chauffeur drop-off points are available nearby, ensuring a seamless and comfortable visit.

Whether you are travelling from elsewhere in London, across the UK or internationally, our clinic offers a calm, private and exclusive setting in one of the world’s leading medical destinations.

Opening hours
Monday
9 am–6 pm
Tuesday
9 am–6 pm
Wednesday
9 am–6 pm
Thursday
9 am–6 pm
Friday
9 am–6 pm
Saturday
Closed
Sunday
Closed
Dr Joney De Souza
49 Blandford St, London W1U 7HH
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