
Doctor-led PRP facial at Dr Joney De Souza Clinic, Marylebone. Regenerative treatment using your own blood to boost collagen and radiance. From £490. Book today.
Regenerative treatment using your own blood to stimulate collagen, improve skin texture and restore natural radiance. Doctor-led. No synthetic materials. Minimal downtime.
If your skin has lost the freshness it used to have, looks tired or uneven, or simply no longer bounces back the way it once did, a PRP facial gives your body the signal to repair itself. Most patients at our Marylebone clinic are in their late twenties to early sixties, though age matters far less than what you see in the mirror. People come to us worried about overall skin condition, early signs of ageing and fading radiance, rather than one isolated feature.
A PRP facial, often searched for as a vampire facial, works especially well for one or more of the following:
PRP is at its best for refreshing and rebuilding skin quality, and because it uses only your own blood there is no risk of allergic reaction. If your priority is restoring lost volume in the cheeks or lips, or lifting heavier jowls and deeper folds, we can combine treatments or guide you to dermal fillers for that. Your practitioner confirms suitability at consultation, and PRP is not recommended if you are pregnant, have an active skin infection at the treatment site, or cannot safely pause blood-thinning medication.

PRP stands for Platelet Rich Plasma. It is a regenerative injectable that uses a highly concentrated preparation of your own plasma to stimulate collagen production, improve skin texture and restore natural radiance.
A small blood sample is drawn at the clinic and spun in a centrifuge to isolate the platelet-rich fraction. That concentrated preparation carries a high level of growth factors. Once injected into targeted areas of the face, those growth factors trigger the skin’s natural repair and renewal response.
New collagen forms, circulation improves, and the skin gradually becomes firmer, smoother and more luminous. Results look natural and build over four to eight weeks after each session, so the change reads as you looking rested rather than treated.
Related treatments at Dr Joney De Souza: PRF, PRP for hair loss and exosome therapy.
Many patients notice improved skin quality, texture and radiance following a course of PRP treatment. Results develop gradually as growth factors stimulate collagen production and tissue regeneration over the weeks following treatment.
Furthermore, patients using PRP for hair restoration often report reduced shedding and increased hair density after a course of sessions. Individual results vary, and Dr De Souza will advise on realistic outcomes at your consultation.




PRP works by concentrating the growth factors already present in your blood and delivering them into the skin at depth. That sets off a controlled regenerative response, stimulating collagen production, tissue repair and better microcirculation across the treated area. In plain terms, it wakes up the skin’s own repair machinery and puts it to work.
Your practitioner draws a small blood sample from your arm before treatment begins. The volume is similar to a standard blood test and takes only a few minutes. The process is straightforward, and most patients find it very comfortable.
The sample then goes into our centrifuge system and spins at high speed. This separates the blood into its component layers, concentrating the platelets and growth factors into a highly active plasma preparation. The result is a consistent, high quality preparation ready for injection.
Once the plasma is ready, your practitioner applies a topical numbing cream across the treatment area and allows it to take full effect before proceeding. Most patients find the injection phase very manageable, and discomfort during PRP injections at our London clinic is minimal.
The concentrated PRP is then injected into targeted areas using fine needles. The technique varies by area and concern, with greater precision applied to delicate zones such as the under-eye area or around the mouth. Each session is tailored to your specific skin goals rather than following a standard protocol.
After the injections are complete, your practitioner reviews the treated area and gives you specific aftercare guidance. Some redness or minor swelling is normal and typically clears within 24 to 48 hours. Most patients return to their normal activities the following day.
Over the following four to eight weeks, growth factors activate the skin’s collagen-producing cells. New blood vessel formation improves microcirculation, gradually brightening and firming the skin as the regenerative process continues. The full benefit of a course usually becomes visible by the three-month mark.
PRP at Dr Joney De Souza Clinic begins with a full medical consultation. Your practitioner reviews your skin health, medical history and treatment goals to confirm suitability and recommend the right number of sessions. A course of two to three sessions spaced four to six weeks apart usually produces the strongest cumulative result.
If you are new to regenerative treatment, PRP is one of the most accessible starting points. It involves no synthetic material, no significant recovery period, and results that build naturally over weeks rather than appearing overnight.
Once you have completed an initial course, a maintenance session once or twice a year typically sustains the improvements you have achieved. Over time, many patients choose to combine PRP with complementary treatments such as
SkinPen microneedling, polynucleotides or skin boosters as their goals evolve.
Your skin is reviewed at each appointment and the treatment approach is adjusted as your skin changes and matures.
As advised at consultation, avoid blood-thinning medications and alcohol in the days before your appointment where medically appropriate. Staying well hydrated helps ensure a good quality blood draw on the day. Our team will contact you beforehand with any specific preparation instructions relevant to your medical history.
PRP treatment takes approximately 45 to 60 minutes in total. Once the topical anaesthetic takes full effect, your practitioner begins the injection sequence. Most patients find the experience very manageable and leave the clinic the same day.
Mild redness, swelling or small injection marks are common in the 24 to 48 hours after treatment, and they usually resolve without any specific intervention. We advise avoiding strenuous exercise, saunas and direct sun exposure during this period so the skin heals more efficiently and the regenerative process develops undisturbed.
At Dr Joney De Souza Clinic, PRP is delivered by practitioners with advanced training in regenerative injectables and a thorough understanding of facial anatomy. Carried out by one of our doctors, Dr Joney De Souza or Dr Mattia Parducci. Your consultation is with Dr Joney De Souza or Dr Mattia Parducci. Every patient completes a full medical consultation before treatment begins, a step that confirms suitability, establishes your skin goals and allows the session to be tailored individually rather than applied as a standard protocol.
“My ‘less is more’ approach has become the mainstay of my practice and clients appreciate that they will have natural looking results” Dr Joney De Souza, The Sybarite
Our patients return to us year after year for results that are natural, balanced and genuinely lasting. PRP has been delivered here across thousands of patient sessions, with both the injection technique and the patient journey refined on clinical outcomes rather than trends.
Every PRP session at our clinic uses CE-certified preparation equipment, producing a consistently high quality plasma preparation at each visit. Treatment takes place in a medically supervised environment, with full aftercare guidance provided before you leave.
By pairing PRP with microneedling to support your skin’s own collagen, the aim is not a quick fix but skin longevity, improving quality, texture and glow while helping preserve the skin’s underlying structure over time.
PRP at Dr Joney De Souza Clinic is priced by the number of areas treated in a single session. Treatment can be applied to the face, neck or decolletage individually, or across two areas in the same appointment for a more comprehensive regenerative result.
One-area treatment is the most common starting point and typically covers the full face. If you have visible concerns across the neck or decolletage, combining areas in a single session makes sense. Treating two areas together costs less than separate bookings and gives a more consistent regenerative result across a wider surface.
| Dr Joney (£) | Associate Clinician (£) | |
|---|---|---|
1 Area (Face OR Neck OR Décolletage) | 575 | 490 |
2 Areas (Face OR Neck OR Décolletage) | 775 | 660 |
SkinPen is an FDA-cleared microneedling device and one of the most clinically validated tools available for skin renewal. At Dr Joney De Souza Clinic, SkinPen is frequently combined with PRP in a single session for patients who want to address texture, scarring and early ageing at the same time. The micro-channels SkinPen creates let PRP reach deeper layers of the skin than topical application achieves alone.
The combined treatment produces a stronger regenerative response than either approach delivers on its own. It suits patients with acne scarring, enlarged pores or uneven skin tone especially well, where surface refinement and deeper collagen stimulation are both needed, and results tend to appear more quickly than after PRP alone. You can read more on our
PRP with SkinPen microneedling page.
The session takes approximately 60 to 90 minutes and recovery is comparable to standalone PRP. Individual suitability depends on your skin concern and current condition. If you would like advice on whether SkinPen with PRP is right for you, WhatsApp our team for a quick recommendation before booking.

Below are the questions patients most commonly ask about PRP treatment for the face. For anything not covered here, WhatsApp our team directly for a quick answer.
At Dr Joney De Souza Clinic in Marylebone, a PRP facial starts from £490 for one area in a single session, with a course of two available from £830. Two-area treatment covering the face plus the neck or decolletage is £660 per session, which costs less than separate bookings. Final pricing depends on the number of areas treated and any additional treatments included in your plan, and your practitioner confirms it at consultation.
PRP stands for Platelet Rich Plasma, a regenerative injectable that uses a concentrated preparation of your own blood to stimulate collagen production, improve skin texture and restore natural radiance. Often searched for as a vampire facial, it involves drawing a small blood sample, processing it to isolate the platelet-rich plasma, and injecting it into targeted areas of the face. Treatment uses only your own blood, so there is no risk of allergic reaction and no synthetic material involved, and results develop progressively over four to eight weeks as the skin’s repair response takes hold. It is one of the most effective ways to treat dull skin and restore a healthy glow.
Most patients benefit from a course of two to three sessions, spaced four to six weeks apart. Each session builds on the regenerative response triggered by the last, producing a cumulative improvement in skin quality, firmness and radiance. Some patients with more pronounced concerns may benefit from additional sessions as part of a longer plan, which your practitioner discusses at consultation.
PRP involves minimal downtime, and most patients return to their normal activities the following day. Mild redness, swelling or small injection marks are common in the 24 to 48 hours after treatment and usually resolve without any specific intervention. We advise avoiding strenuous exercise, saunas and direct sun exposure during this period so the skin heals efficiently and the regenerative process develops undisturbed.
Most patients notice early improvements in skin texture and radiance within two to four weeks of their first session. Firmer, smoother skin with a more even tone typically becomes visible at six to eight weeks. The full benefit of a course is usually apparent by three months, and a course of two to three sessions typically delivers results lasting twelve to eighteen months. A maintenance session once or twice a year is usually enough to sustain the improvements you have achieved.
PRP is one of the safest treatments available in aesthetic medicine because it uses nothing but your own blood. There is no synthetic material, no donor tissue and no risk of allergic reaction. CE-certified preparation equipment is used at every session, producing a consistently high quality plasma preparation. As with any injectable treatment, there is a small risk of bruising or temporary redness, which typically resolves within 48 hours.
PRP and PRF both use your own blood, but they are prepared differently and behave differently in the skin. PRF (Platelet Rich Fibrin) is spun more slowly and without additives, so it forms a natural fibrin scaffold that releases growth factors gradually over several days, whereas PRP delivers a more immediate concentration. Your practitioner selects the right option for your skin at consultation. You can compare our full regenerative range through the PRP and PRF hub, or read more about PRF and PRP for hair loss.
Yes, and combining PRP with microneedling often produces a stronger result than either treatment alone. PRP is frequently paired with SkinPen microneedling, where the micro-channels enhance PRP absorption and amplify collagen stimulation. It works particularly well for acne scarring, enlarged pores and uneven skin tone, where surface refinement and deeper collagen stimulation are both needed. You can read more about the combined treatment on our PRP with SkinPen microneedling page, or explore the exosome treatment for another regenerative option.
Carried out by one of our doctors, Dr Joney De Souza or Dr Mattia Parducci. Your consultation is with Dr Joney De Souza or Dr Mattia Parducci. Your practitioner assesses you for suitability before treatment begins and refines the injection technique to your individual anatomy rather than applying a standard protocol. Because the quality of PRP depends heavily on the preparation system and the skill of the practitioner, this doctor-led approach at our Marylebone clinic gives you a consistent, medical standard of care.
You can contact us by WhatsApp, phone or email, or you can book your treatment online. Dr Joney De Souza Clinic is in Marylebone, central London, within easy reach of Bond Street, Baker Street and Marble Arch tube stations. Every course begins with a full medical consultation, so your practitioner confirms your suitability and treatment plan before any PRP facial goes ahead.
Our patients return to us year after year for natural, balanced results. Every review reflects our commitment to precision, safety and a personalised approach to aesthetic care.