
Lumieyes is an advanced, non-surgical treatment designed to rejuvenate the delicate under eye area by improving skin quality, hydration and firmness.
Lumieyes suits patients who are concerned about the appearance of the under-eye area. Whether you experience dark circles, fine lines, hollowing or thin skin beneath the eyes, this treatment addresses the underlying skin quality rather than masking it with volume or filler.
You may benefit from Lumieyes treatment in Marylebone if:
Lumieyes is a specialist PDRN (polydeoxyribonucleotide) treatment developed specifically for the delicate periorbital skin. Lumieyes draws on PDRN sourced from purified salmon DNA. The polynucleotide fragments stimulate collagen synthesis, improve hydration and accelerate cellular repair in the dermis.
Unlike standard polynucleotide treatments, Lumieyes uses a formulation specifically adapted for the thin, sensitive skin around the eye. The product concentration, needle gauge and injection protocol are all tailored to this fragile area. Furthermore, the treatment works at a biological level rather than by adding volume, making results look natural and progressive rather than immediate and artificial.
In practice, Dr Joney De Souza administers Lumieyes through a precise series of micro-injections into the dermis beneath and around the eye. Each injection delivers PDRN directly to the target tissue, where it triggers a biological repair response. The treatment takes approximately 30 to 45 minutes in full, including preparation and the injection protocol.
At your consultation, Dr De Souza assesses the under-eye area in person, discusses your concerns and confirms whether Lumieyes is appropriate for your skin type and presentation. He also reviews your medical history and any medications. Additionally, he takes photographs to allow comparison after treatment.
In practice, Dr De Souza applies a topical numbing cream to the under-eye area before the injections begin. This takes approximately 20 minutes to take full effect. During this time, the Lumieyes solution is prepared and Dr De Souza maps out the injection protocol to target the areas of most concern.
The injections are administered with a very fine needle designed for the periorbital area, which minimises discomfort significantly. Most patients describe a mild prickling sensation rather than pain. However, the under-eye area is more sensitive than other parts of the face. Topical anaesthetic and a careful technique keep the procedure comfortable throughout for most patients.
After the injections, you may notice mild redness and small raised bumps at the injection sites. In most cases, these resolve within a few hours. Dr De Souza advises avoiding makeup around the eye area for 24 hours and keeping the skin clean. Additionally, you should avoid rubbing the under-eye area for the rest of the day.
Results from Lumieyes build progressively over the weeks following each session. In practice, patients typically notice an improvement in skin hydration and texture within two to four weeks of the first session. Collagen production continues to increase over the following months, with the best results visible four to six weeks after completing the recommended course.
Dr De Souza typically recommends one to three sessions depending on the severity of the under-eye concerns. Dr De Souza spaces sessions four to six weeks apart to allow the biological repair process to complete between treatments. Overall, patients with moderate concerns tend to see the most significant transformation across a course of two or three sessions.
A course of Lumieyes at Dr Joney De Souza Clinic typically consists of one to three sessions spaced four to six weeks apart. The spacing allows the PDRN to complete each regenerative cycle before the next treatment builds on it. Most patients notice a visible improvement in under-eye texture and brightness after the first session, with the most significant results appearing four to six weeks after the final treatment.
At your consultation, Dr De Souza reviews your skin type, medical history and current skincare routine. In the days before treatment, he recommends avoiding blood-thinning medications such as aspirin or ibuprofen unless prescribed, as these increase the risk of bruising. You should also avoid alcohol for 24 hours before your session. Additionally, the treatment area should be free from active infection or skin irritation on the day.
Your appointment lasts approximately 30 to 45 minutes. After Dr De Souza applies topical numbing cream and it takes effect, he performs the Lumieyes injection protocol. He uses very fine needles designed for the periorbital area, with precise placement targeting the dermis beneath the eye. Most patients find the procedure well tolerated throughout. Furthermore, Dr De Souza adjusts the injection depth and volume for each patient based on the specific presentation of their under-eye concerns.
After treatment, mild redness and small bumps at the injection sites are normal and typically resolve within a few hours. In practice, most patients are comfortable to go about their day afterwards. Dr De Souza advises avoiding makeup around the eye area for 24 hours, refraining from rubbing the treated area, and applying SPF the following morning. Furthermore, you should avoid strenuous exercise for 24 hours and alcohol for 48 hours after treatment.
The under-eye area requires exceptional precision. In practice, Dr Joney De Souza has over 20 years of clinical experience and an advanced understanding of periorbital anatomy. His Marylebone clinic administers Lumieyes under a strict medical protocol, with every treatment performed or directly supervised by a doctor.
The under-eye area is one of the most technically demanding areas in aesthetic medicine. Dr De Souza selects the Lumieyes formulation specifically for its established safety profile and the precision of its delivery protocol. Patients receive a written aftercare plan and a review appointment after their course to assess results and plan any maintenance treatment.
Lumieyes Marylebone treatment is available at associate practitioner pricing and at Dr Joney De Souza pricing. In practice, both tiers deliver the same premium Lumieyes formulation and clinical protocol. The difference reflects the experience level of the treating practitioner.
Both Associate and Dr Joney De Souza pricing available. Dr Joney recommends a course of 2 sessions.
| Price (£) | |
|---|---|
Lumieyes - single session ( therapist) | 325 |
Lumieyes - two sessions ( therapist) | 555 |
Lumieyes - single session ( Dr Joney) | 380 |
Lumieyes - two sessions ( Dr Joney) | 650 |
Lumieyes targets the under-eye area specifically, but many patients also benefit from treating the broader face, neck or décolletage with standard polynucleotide therapy. Polynucleotides (PDRN) work through the same biological mechanism as Lumieyes, stimulating fibroblast activity and collagen production across a larger treatment zone.
In practice, patients who combine a course of Lumieyes for the under-eye area with polynucleotide treatment for the full face achieve a more balanced and comprehensive skin quality improvement. Dr De Souza will advise at consultation whether a combined approach suits your skin concerns and whether the treatments can be scheduled in the same session or separately.

Below are the most common questions from patients considering Lumieyes London. This section covers all aspects of Lumieyes treatment London at Dr Joney De Souza Clinic, Marylebone, including Lumieyes under-eye injections, pricing and suitability.
Lumieyes improves skin quality beneath the eyes by stimulating collagen and elastin production, increasing hydration and improving the skin barrier. However, it works progressively rather than instantly. Most patients notice improved brightness and texture within two to four weeks of their first session. Overall, the most significant improvement in dark circles, fine lines and skin firmness appears four to six weeks after completing the recommended course.
Lumieyes is suitable for most adults who are experiencing dark circles, fine lines, hollowing or thinning under-eye skin. In most cases, it is safe for all skin tones. However, Dr De Souza does not recommend Lumieyes during pregnancy or while breastfeeding. He also avoids treatment over active skin infections or very severe puffiness that may have an underlying medical cause.
Lumieyes works best for dark circles caused by skin thinning, poor circulation and loss of dermal density beneath the eye. However, dark circles caused primarily by deep hollowing or significant volume loss may respond better to tear trough filler rather than Lumieyes alone. In practice, Dr De Souza assesses the type and cause of dark circles at consultation to recommend the most appropriate treatment approach.
The treatment is well tolerated by most patients. Topical numbing cream is applied before the injections to minimise discomfort. However, the under-eye area is more sensitive than other parts of the face, so some patients notice more sensation during treatment. Overall, the fine-gauge needle used for Lumieyes significantly reduces discomfort compared to standard injectable treatments.
Visible improvement in skin texture and hydration beneath the eyes typically appears within two to four weeks of the first session. However, collagen remodelling is a gradual biological process and the most significant results develop over the full course of treatment. In practice, patients who complete two to three sessions see the best cumulative improvement in dark circles, firmness and line reduction.
Dr De Souza recommends one to three sessions depending on the severity of the under-eye concerns. For most patients, a course of two sessions spaced four to six weeks apart delivers the best improvement. However, patients with more pronounced concerns, such as significant thinning or deep pigmentation beneath the eyes, may benefit from a third session. A review appointment after the course allows Dr De Souza to assess results and plan any maintenance treatment needed.
Downtime is minimal. Mild redness and small bumps at the injection sites are common for a few hours after treatment, but these typically resolve the same day. In most cases, patients can return to work and normal activities immediately. However, you should avoid makeup around the eye area for 24 hours, strenuous exercise for 24 hours and alcohol for 48 hours. Bruising is possible but uncommon, and if it occurs, it generally resolves within five to seven days.
Yes. Lumieyes works well alongside a range of complementary treatments. Many patients combine Lumieyes with standard polynucleotide treatment for the face to achieve broader skin quality improvement. It can also be scheduled alongside Profhilo, mesotherapy or non-surgical tear trough filler for a more comprehensive approach. Dr De Souza advises on the most effective combination and sequencing at consultation.
PDRN-based treatments including Lumieyes have a well-established safety profile, supported by clinical studies in both aesthetic medicine and wound healing applications. As an injectable treatment, there is a small risk of temporary redness, bruising or swelling at injection sites. However, the product does not contain any cross-linked gel or foreign material, and the risk of adverse reaction is very low. Consequently, Dr De Souza reviews your full medical history before treatment.
Lumieyes is not suitable during pregnancy or while breastfeeding. Patients with active infections, open wounds or skin conditions in the treatment area should wait until these have resolved. Furthermore, patients with a history of severe allergy to fish or fish products should inform Dr De Souza at consultation, as PDRN is derived from salmon DNA. In most cases, Dr De Souza can identify an appropriate alternative if Lumieyes is not suitable.
Results from a course of Lumieyes typically last six to twelve months, depending on age, lifestyle, skincare habits and the severity of the initial presentation. In practice, patients who follow a good SPF routine and maintain skin hydration with suitable products tend to retain results longer. A maintenance session every six to nine months is common among patients who want to sustain the skin quality improvement over time.
Understanding how Lumieyes compares to other treatments for the under-eye area helps you make an informed decision about the right approach for your skin and goals.
Tear trough filler adds volume to the hollow beneath the eye using hyaluronic acid gel. Lumieyes, by contrast, improves the quality of the skin itself through biological stimulation. In practice, filler works best for patients whose primary concern is hollowing and volume loss. Lumieyes works best for patients whose concern is skin quality, dark circles and fine lines. For patients with both issues, Dr De Souza may recommend a combined approach, sequencing the treatments appropriately.
Standard polynucleotide treatments use similar PDRN technology but target larger areas such as the full face, neck and décolletage. Lumieyes uses a formulation specifically adapted for the thin, sensitive periorbital skin, with a lower concentration and a finer needle gauge suited to the delicate anatomy of the eye area. In most cases, Lumieyes and polynucleotides can be used together as complementary rather than competing treatments.
Profhilo is a hyaluronic acid biostimulator that improves overall skin hydration and early laxity across the face and neck. However, Profhilo is not typically injected in the periorbital area due to the risk of migration and swelling in such a thin-skinned region. Lumieyes is specifically designed for under-eye injection and addresses the unique biology of the periorbital skin. Consequently, it is the more appropriate choice for targeted eye-area treatment.
Mesotherapy for the under-eye area delivers vitamins, amino acids and hyaluronic acid via micro-injections to nourish and hydrate the skin. Lumieyes works at a deeper biological level, stimulating collagen synthesis and cellular repair through PDRN signalling. In practice, Lumieyes tends to produce more significant structural improvement over time, while mesotherapy provides faster surface hydration. Both are appropriate options, and the best choice depends on your specific presentation and goals.
Lumieyes addresses skin quality and dark circles caused by dermal thinning and poor circulation. However, it cannot address under-eye bags caused by herniated orbital fat or significant excess skin. These structural issues require surgical treatment such as lower blepharoplasty. Dr De Souza will assess whether your under-eye concerns are best addressed non-surgically or whether surgical referral would be more appropriate at your consultation.
PRP (platelet-rich plasma) uses growth factors from the patient’s own blood to stimulate tissue repair. Lumieyes uses standardised pharmaceutical-grade PDRN with a consistent potency per vial. In practice, Lumieyes tends to be more predictable in terms of regenerative signal delivery, as PRP concentration varies between patients. Additionally, the specific Lumieyes periorbital protocol is designed for the precision demands of the under-eye anatomy.
Retinol creams increase cell turnover at the surface and can reduce fine lines over time, but they work only at the epidermis. Lumieyes delivers regenerative signals directly into the dermis via injection, stimulating deeper structural change. Furthermore, retinol products are often irritating around the sensitive eye area and are contraindicated during pregnancy. Lumieyes produces a more significant dermal response and is well tolerated in this area when administered by an experienced practitioner.
Laser and energy treatments around the eye require significant precision and caution due to the proximity of the eyeball and thin periorbital skin. In practice, many laser devices cannot be safely used this close to the eye without specific eye shields and protocols. Lumieyes carries no thermal risk and works through biological regeneration rather than controlled injury. For most patients, Lumieyes is the safer and more comfortable option for under-eye skin quality improvement.
Both Lumieyes and exosome therapy use biological signalling to stimulate skin regeneration. Exosomes work through cellular communication signals delivered topically after microneedling. Lumieyes delivers PDRN directly into the dermis through injection. In practice, injection delivers the active compound deeper and more precisely into the target tissue beneath the eye. However, microneedling around the periorbital area requires care and is generally limited to slightly more superficial depths than injectable Lumieyes treatment.
Overall, the best way to determine whether Lumieyes is appropriate for your under-eye concerns is a consultation with Dr Joney De Souza. At your appointment, he assesses the anatomy and skin quality of the under-eye area, identifies the likely cause of your concerns, and recommends the most effective treatment approach. In some cases, this may be Lumieyes alone; in others, a combination of Lumieyes with filler, polynucleotides or other treatments may produce the best result. Book a consultation via WhatsApp or the contact form on this page.
Our patients return to us year after year for natural, balanced results. Every review reflects our commitment to precision, safety and a personalised approach to aesthetic care.
I had a course of Lumieyes with Dr Joney and the improvement to my dark circles and under-eye skin is remarkable. Overall, I look more rested and the results are completely natural. The clinic is exceptional throughout.
Dr De Souza is incredibly skilled. My under-eye area looks so much better after Lumieyes and I am delighted with the results. Additionally, the treatment was comfortable and the whole team were wonderful.
The improvement in my under-eye skin after Lumieyes has been wonderful. The treatment was quick, comfortable and the aftercare was thorough. Furthermore, I feel much more confident without concealer. Highly recommended.
Fantastic clinic and brilliant results. Dr Joney took time to explain everything and my Lumieyes results exceeded my expectations. My dark circles are so much better and my skin looks healthier.